Most cited biochemistry, genetics and molecular biology papers
- Verified
Autophagy-deficient mice develop multiple liver tumors
Takamura, A., Komatsu, M., Hara, T., Sakamoto, A., Kishi, C., Waguri, S., Eishi, Y., Hino, O., Tanaka, K., & Mizushima, N. (2011) · Genes & Development
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 1,342
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Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
Treutlein, B., Brownfield, D. G., Wu, A. R., Neff, N. F., Mantalas, G. L., Espinoza, F. H., Desai, T. J., Krasnow, M. A., & Quake, S. R. (2014) · Nature
Single-cell and spatial transcriptomicsNeonatal Respiratory Health Research
Cited by 1,342
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Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
Liesa, M., & Shirihai, O. S. (2013) · Cell Metabolism
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 1,341
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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216
Peng, C.-Y., Graves, P. R., Thoma, R. S., Wu, Z., Shaw, A. S., & Piwnica-Worms, H. (1997) · Science
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,341
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Epigenetic plasticity and the hallmarks of cancer
Flavahan, W. A., Gaskell, E., & Bernstein, B. E. (2017) · Science
Epigenetics and DNA MethylationChromatin Remodeling and Cancer
Cited by 1,340
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Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication
Ratajczak, J., Wysoczynski, M., Hayek, F., Janowska-Wieczorek, A., & Ratajczak, M. Z. (2006) · Leukemia
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 1,340
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Hypoxic control of metastasis
Rankin, E. B., & Giaccia, A. J. (2016) · Science
Cancer, Hypoxia, and MetabolismMechanisms of cancer metastasis
Cited by 1,340
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Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells
Zwaal, R. F. A., & Schroit, A. J. (1997) · Blood
Lipid Membrane Structure and BehaviorErythrocyte Function and Pathophysiology
Cited by 1,340
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Microarray data analysis: from disarray to consolidation and consensus
Allison, D. B., Cui, X., Page, G. P., & Sabripour, M. (2006) · Nature Reviews Genetics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 1,339
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Parental olfactory experience influences behavior and neural structure in subsequent generations
Dias, B. G., & Ressler, K. J. (2014) · Nature Neuroscience
Epigenetics and DNA MethylationOlfactory and Sensory Function Studies
Cited by 1,338
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Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
Behan, F. M., Iorio, F., Picco, G., Gonçalves, E., Beaver, C. M., Migliardi, G., Santos, R., Rao, Y., Sassi, F., Pinnelli, M., et al. (2019) · Nature
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 1,338
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The plasticity of aging: insights from long-lived mutants
Kenyon, C. (2005) · Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 1,338
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Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
Demaria, M., O'Leary, M. N., Chang, J., Shao, L., Liu, S., Alimirah, F., Koenig, K., Le, C., Mitin, N., Deal, A. M., et al. (2017) · Cancer Discovery
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,338
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Multiscale 3D Genome Rewiring during Mouse Neural Development
Bonev, B., Mendelson Cohen, N., Szabo, Q., Fritsch, L., Papadopoulos, G. L., Lubling, Y., Xu, X., Lv, X., Hugnot, J.-P., Tanay, A., et al. (2017) · Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,338
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Superoxide Anion Radical (O·̄2), Superoxide Dismutases, and Related Matters
Fridovich, I. (1997) · Journal of Biological Chemistry
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,337
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Three-dimensional culture models of normal and malignant breast epithelial cells
Lee, G. Y., Kenny, P. A., Lee, E. H., & Bissell, M. J. (2007) · Nature Methods
Cellular Mechanics and Interactions3D Printing in Biomedical Research
Cited by 1,336
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Therapeutic genome editing: prospects and challenges
Cox, D. B. T., Platt, R. J., & Zhang, F. (2015) · Nature Medicine
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,336
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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
Miao, E. A., Leaf, I. A., Treuting, P. M., Mao, D. P., Dors, M., Sarkar, A., Warren, S. E., Wewers, M. D., & Aderem, A. (2010) · Nature Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,336
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The gut microbiome in neurological disorders
Cryan, J. F., O'Riordan, K. J., Sandhu, K., Peterson, V., & Dinan, T. G. (2020) · The Lancet Neurology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,336
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Mitochondrial metabolism of reactive oxygen species
Andreyev, A. Y., Kushnareva, Y. E., & Starkov, A. A. (2005) · Biochemistry (Moscow)
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 1,336
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Triggering and modulation of apoptosis by oxidative stress
Chandra, J., Samali, A., & Orrenius, S. (2000) · Free Radical Biology and Medicine
Cell death mechanisms and regulationRedox biology and oxidative stress
Cited by 1,335
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Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate
Brash, A. R. (1999) · Journal of Biological Chemistry
Eicosanoids and Hypertension PharmacologyMetal-Catalyzed Oxygenation Mechanisms
Cited by 1,335
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HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
Semenza, G. L. (2013) · Journal of Clinical Investigation
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,335
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Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells
Reigstad, C. S., Salmonson, C. E., III, J. F. R., Szurszewski, J. H., Linden, D. R., Sonnenburg, J. L., Farrugia, G., & Kashyap, P. C. (2015) · The FASEB Journal
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,335
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