Most cited biochemistry, genetics and molecular biology papers
- Verified
Bayesian phylogenetic inference using DNA sequences: a Markov Chain Monte Carlo Method
Yang, Z., & Rannala, B. (1997) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesGenetic diversity and population structure
Cited by 1,274
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Matrix metalloproteinases: they're not just for matrix anymore!
McCawley, L. J., & Matrisian, L. M. (2001) · Current Opinion in Cell Biology
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 1,274
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How Proteolysis Drives the Cell Cycle
King, R. W., Deshaies, R. J., Peters, J.-M., & Kirschner, M. W. (1996) · Science
Ubiquitin and proteasome pathwaysMicrotubule and mitosis dynamics
Cited by 1,273
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Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
Zhang, X.-H., Tee, L. Y., Wang, X.-G., Huang, Q.-S., & Yang, S.-H. (2015) · Molecular Therapy - Nucleic Acids
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,273
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Guidelines for performing Mendelian randomization investigations
Burgess, S., Davey Smith, G., Davies, N. M., Dudbridge, F., Gill, D., Glymour, M. M., Hartwig, F. P., Holmes, M. V., Minelli, C., Relton, C. L., et al. (2020) · Wellcome Open Research
Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques
Cited by 1,273
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Somatic coding mutations in human induced pluripotent stem cells
Gore, A., Li, Z., Fung, H.-L., Young, J. E., Agarwal, S., Antosiewicz-Bourget, J., Canto, I., Giorgetti, A., Israel, M. A., Kiskinis, E., et al. (2011) · Nature
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 1,273
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Cellular Adaptation to Hypoxia through Hypoxia Inducible Factors and beyond
Lee, P., Chandel, N. S., & Simon, M. C. (2020) · Nature Reviews Molecular Cell Biology
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 1,272
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Disorders of Bone Remodeling
Feng, X., & McDonald, J. M. (2011) · Annual Review of Pathology: Mechanisms of Disease
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,272
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A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes
MacArthur, D. G., Balasubramanian, S., Frankish, A., Huang, N., Morris, J., Walter, K., Jostins, L., Habegger, L., Pickrell, J. K., Montgomery, S. B., et al. (2012) · Science
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 1,272
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Advanced maturation of human cardiac tissue grown from pluripotent stem cells
Ronaldson-Bouchard, K., Ma, S. P., Yeager, K., Chen, T., Song, L., Sirabella, D., Morikawa, K., Teles, D., Yazawa, M., & Vunjak-Novakovic, G. (2018) · Nature
Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias
Cited by 1,272
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Long-Term Results of a Randomized Trial Comparing Breast-Conserving Therapy With Mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial
van Dongen, J. A. (2000) · Journal of the National Cancer Institute
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 1,271
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ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
Hashimoto, T., Perlot, T., Rehman, A., Trichereau, J., Ishiguro, H., Paolino, M., Sigl, V., Hanada, T., Hanada, R., Lipinski, S., et al. (2012) · Nature
Gut microbiota and healthInflammatory Bowel Disease
Cited by 1,271
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Molecular Architecture of the Rotary Motor in ATP Synthase
Stock, D., Leslie, A. G. W., & Walker, J. E. (1999) · Science
ATP Synthase and ATPases ResearchEnzyme Structure and Function
Cited by 1,271
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A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
Hein, M. Y., Hubner, N. C., Poser, I., Cox, J., Nagaraj, N., Toyoda, Y., Gak, I. A., Weisswange, I., Mansfeld, J., Buchholz, F., et al. (2015) · Cell
Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications
Cited by 1,270
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Persistent gut microbiota immaturity in malnourished Bangladeshi children
Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., et al. (2014) · Nature
Gut microbiota and healthChild Nutrition and Water Access
Cited by 1,270
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Phylogenetic Shadowing and Computational Identification of Human microRNA Genes
Berezikov, E., Guryev, V., van de Belt, J., Wienholds, E., Plasterk, R. H. A., & Cuppen, E. (2005) · Cell
MicroRNA in disease regulationChromosomal and Genetic Variations
Cited by 1,270
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Cellular Senescence: Aging, Cancer, and Injury
Calcinotto, A., Kohli, J., Zagato, E., Pellegrini, L., Demaria, M., & Alimonti, A. (2019) · Physiological Reviews
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,270
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Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
Meléndez, A., Tallóczy, Z., Seaman, M., Eskelinen, E.-L., Hall, D. H., & Levine, B. (2003) · Science
Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy
Cited by 1,270
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Mitochondrial dynamics and apoptosis
Suen, D.-F., Norris, K. L., & Youle, R. J. (2008) · Genes & Development
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 1,270
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Essential role of mouse telomerase in highly proliferative organs
Lee, H.-W., Blasco, M. A., Gottlieb, G. J., Horner, J. W., Greider, C. W., & DePinho, R. A. (1998) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,270
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Sensitivity of CaM Kinase II to the Frequency of Ca 2+ Oscillations
De Koninck, P., & Schulman, H. (1998) · Science
Protein Kinase Regulation and GTPase SignalingNeuroscience and Neuropharmacology Research
Cited by 1,269
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Metalloproteins and metal sensing
Waldron, K. J., Rutherford, J. C., Ford, D., & Robinson, N. J. (2009) · Nature
Metalloenzymes and iron-sulfur proteinsTrace Elements in Health
Cited by 1,269
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Cell death by mitotic catastrophe: a molecular definition
Castedo, M., Perfettini, J.-L., Roumier, T., Andreau, K., Medema, R., & Kroemer, G. (2004) · Oncogene
Cell death mechanisms and regulationMicrotubule and mitosis dynamics
Cited by 1,269
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Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
Helwak, A., Kudla, G., Dudnakova, T., & Tollervey, D. (2013) · Cell
MicroRNA in disease regulationRNA Research and Splicing
Cited by 1,269
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