Most cited biochemistry, genetics and molecular biology papers
- Verified
A Novel Breast Cancer–Associated BRIP1 ( FANCJ/BACH1 ) Germ-line Mutation Impairs Protein Stability and Function
De Nicolo, A., Tancredi, M., Lombardi, G., Flemma, C. C., Barbuti, S., Di Cristofano, C., Sobhian, B., Bevilacqua, G., Drapkin, R., & Caligo, M. A. (2008) · Clinical Cancer Research
BRCA gene mutations in cancerDNA Repair Mechanisms
Cited by 91
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Bursts and pulses: Insights from single cell studies into transcriptional mechanisms
Chubb, J. R., & Liverpool, T. B. (2010) · Current Opinion in Genetics & Development
Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics
Cited by 91
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ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle
Das, S., Morvan, F., Jourde, B., Meier, V., Kahle, P., Brebbia, P., Toussaint, G., Glass, D. J., & Fornaro, M. (2015) · Cell Metabolism
Mitochondrial Function and PathologyMuscle Physiology and Disorders
Cited by 91
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Cancer chromosomes in crisis
DePinho, R. A., & Polyak, K. (2004) · Nature Genetics
Telomeres, Telomerase, and SenescenceMicrotubule and mitosis dynamics
Cited by 91
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Application of a Persistent Heparin Treatment Inhibits the Malignant Potential of Oral Squamous Carcinoma Cells Induced by Tumor Cell-Derived Exosomes
Sento, S., Sasabe, E., & Yamamoto, T. (2016) · PLOS ONE
Extracellular vesicles in diseaseCancer Cells and Metastasis
Cited by 91
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The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury
Tauchi, R., Imagama, S., Natori, T., Ohgomori, T., Muramoto, A., Shinjo, R., Matsuyama, Y., Ishiguro, N., & Kadomatsu, K. (2012) · Journal of Neuroinflammation
Proteoglycans and glycosaminoglycans researchSpinal Cord Injury Research
Cited by 91
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Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms
Abyzov, A., Li, S., Kim, D. R., Mohiyuddin, M., Stütz, A. M., Parrish, N. F., Mu, X. J., Clark, W., Chen, K., Hurles, M., et al. (2015) · Nature Communications
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 91
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A Phospholipid Transfer Function of ER-Mitochondria Encounter Structure Revealed in Vitro
Kojima, R., Endo, T., & Tamura, Y. (2016) · Scientific Reports
Mitochondrial Function and PathologyCellular transport and secretion
Cited by 91
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Complex II Defect via Down-regulation of Iron-Sulfur Subunit Induces Mitochondrial Dysfunction and Cell Cycle Delay in Iron Chelation-induced Senescence-associated Growth Arrest
Yoon, Y.-S., Byun, H.-O., Cho, H., Kim, B.-K., & Yoon, G. (2003) · Journal of Biological Chemistry
Mitochondrial Function and PathologyTelomeres, Telomerase, and Senescence
Cited by 91
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Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers
Maussion, G., Yang, J., Yerko, V., Barker, P., Mechawar, N., Ernst, C., & Turecki, G. (2012) · PLoS ONE
MicroRNA in disease regulationSuicide and Self-Harm Studies
Cited by 91
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G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog
Pusapati, G. V., Kong, J. H., Patel, B. B., Gouti, M., Sagner, A., Sircar, R., Luchetti, G., Ingham, P. W., Briscoe, J., & Rohatgi, R. (2018) · Science Signaling
Hedgehog Signaling Pathway StudiesReceptor Mechanisms and Signaling
Cited by 91
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Glucocorticoid and cytokine crosstalk: Feedback, feedforward, and co-regulatory interactions determine repression or resistance
Newton, R., Shah, S., Altonsy, M. O., & Gerber, A. N. (2017) · Journal of Biological Chemistry
Estrogen and related hormone effectsCytokine Signaling Pathways and Interactions
Cited by 91
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PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis
Yamaguchi, N., Weinberg, E. M., Nguyen, A., Liberti, M. V., Goodarzi, H., Janjigian, Y. Y., Paty, P. B., Saltz, L. B., Kingham, T. P., Loo, J. M., et al. (2019) · eLife
Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research
Cited by 91
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Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development
Miyamoto, K., Teperek, M., Yusa, K., Allen, G. E., Bradshaw, C. R., & Gurdon, J. B. (2013) · Science
Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics
Cited by 91
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Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Wickramasinghe, V. O., Gonzàlez-Porta, M., Perera, D., Bartolozzi, A. R., Sibley, C. R., Hallegger, M., Ule, J., Marioni, J. C., & Venkitaraman, A. R. (2015) · Genome Biology
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 91
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Pharmacologic modification of tumor blood flow and interstitial fluid pressure in a human tumor xenograft: network analysis and mechanistic interpretation
Zlotecki, R. A., Baxter, L. T., Boucher, Y., & Jain, R. K. (1995) · Microvascular Research
Angiogenesis and VEGF in CancerMathematical Biology Tumor Growth
Cited by 91
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Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations
Stražar, M., Temba, G. S., Vlamakis, H., Kullaya, V. I., Lyamuya, F., Mmbaga, B. T., Joosten, L. A. B., van der Ven, A. J. A. M., Netea, M. G., de Mast, Q., et al. (2021) · Nature Communications
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 91
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Prostate Cancer Associated with p53 and Rb Deficiency Arises from the Stem/Progenitor Cell–Enriched Proximal Region of Prostatic Ducts
Zhou, Z., Flesken-Nikitin, A., & Nikitin, A. Y. (2007) · Cancer Research
Prostate Cancer Treatment and ResearchCancer Cells and Metastasis
Cited by 91
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Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1α and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway
Jin, H.-O., An, S., Lee, H.-C., Woo, S.-H., Seo, S.-K., Choe, T.-B., Yoo, D.-H., Lee, S.-B., Um, H.-D., & Lee, S.-J. (2007) · Cellular Signalling
Cancer, Hypoxia, and MetabolismHeat shock proteins research
Cited by 91
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Role of the dinB Gene Product in Spontaneous Mutation in Escherichia coli with an Impaired Replicative Polymerase
Strauss, B. S., Roberts, R., Francis, L., & Pouryazdanparast, P. (2000) · Journal of Bacteriology
DNA Repair MechanismsBacterial Genetics and Biotechnology
Cited by 91
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γN‐crystallin and the evolution of the βγ‐crystallin superfamily in vertebrates
Wistow, G., Wyatt, K., David, L., Gao, C., Bateman, O., Bernstein, S., Tomarev, S., Segovia, L., Slingsby, C., & Vihtelic, T. (2005) · The FEBS Journal
Developmental Biology and Gene RegulationOcular Disorders and Treatments
Cited by 91
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Localization of Peptidases in Lactococci
Tan, P. S. T., Chapot-Chartier, M.-P., Pos, K. M., Rousseau, M., Boquien, C.-Y., Gripon, J.-C., & Konings, W. N. (1992) · Applied and Environmental Microbiology
Bacterial Genetics and BiotechnologyEnzyme Production and Characterization
Cited by 91
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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application
O’Brien, M. E., Murray, G., Gogoi, D., Yusuf, A., McCarthy, C., Wormald, M. R., Casey, M., Gabillard-Lefort, C., McElvaney, N. G., & Reeves, E. P. (2022) · International Journal of Molecular Sciences
Protease and Inhibitor MechanismsNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 91
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Mesenchymal stem/stromal cells in post-menopausal endometrium
Ulrich, D., Tan, K. S., Deane, J., Schwab, K., Cheong, A., Rosamilia, A., & Gargett, C. E. (2014) · Human Reproduction
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 91
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