Most cited biochemistry, genetics and molecular biology papers
- Verified
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
McArthur, K., Whitehead, L. W., Heddleston, J. M., Li, L., Padman, B. S., Oorschot, V., Geoghegan, N. D., Chappaz, S., Davidson, S., San Chin, H., et al. (2018) · Science
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,072
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Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group
Karvonen, M., Viik-Kajander, M., Moltchanova, E., Libman, I., LaPorte, R., & Tuomilehto, J. (2000) · Diabetes Care
Diabetes and associated disordersDiabetes Management and Research
Cited by 1,072
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The role of sialic acid in determining the survival of glycoproteins in the circulation
Morell, A. G., Gregoriadis, G., Scheinberg, I. H., Hickman, J., & Ashwell, G. (1971) · Journal of Biological Chemistry
Glycosylation and Glycoproteins ResearchProteoglycans and glycosaminoglycans research
Cited by 1,072
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A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., et al. (2007) · Nature Genetics
Genetic Associations and EpidemiologyPancreatic function and diabetes
Cited by 1,072
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Th17 cell induction by adhesion of microbes to intestinal epithelial cells
Atarashi, K., Tanoue, T., Ando, M., Kamada, N., Nagano, Y., Narushima, S., Suda, W., Imaoka, A., Setoyama, H., Nagamori, T., et al. (2015) · Cell
Gut microbiota and healthPsoriasis: Treatment and Pathogenesis
Cited by 1,071
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Identification of ACSL4 as a biomarker and contributor of ferroptosis
Yuan, H., Li, X., Zhang, X., Kang, R., & Tang, D. (2016) · Biochemical and Biophysical Research Communications
Ferroptosis and cancer prognosisIron Metabolism and Disorders
Cited by 1,071
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A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications
Haque, A., Engel, J., Teichmann, S. A., & Lönnberg, T. (2017) · Genome Medicine
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,071
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Endothelial Notch activity promotes angiogenesis and osteogenesis in bone
Ramasamy, S. K., Kusumbe, A. P., Wang, L., & Adams, R. H. (2014) · Nature
Angiogenesis and VEGF in CancerBone Metabolism and Diseases
Cited by 1,071
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Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
McGehee, D. S., Heath, M. J. S., Gelber, S., Devay, P., & Role, L. W. (1995) · Science
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 1,070
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Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986) · Cell
Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling
Cited by 1,070
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Combinatorial drug therapy for cancer in the post-genomic era
Al-Lazikani, B., Banerji, U., & Workman, P. (2012) · Nature Biotechnology
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 1,070
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Preparation of Hydrogel Substrates with Tunable Mechanical Properties
Tse, J. R., & Engler, A. J. (2010) · Current Protocols in Cell Biology
Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications
Cited by 1,070
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Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues
Gao, G., Vandenberghe, L. H., Alvira, M. R., Lu, Y., Calcedo, R., Zhou, X., & Wilson, J. M. (2004) · Journal of Virology
Virus-based gene therapy researchParvovirus B19 Infection Studies
Cited by 1,070
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Telomere end-replication problem and cell aging
Levy, M. Z., Allsopp, R. C., Futcher, A. B., Greider, C. W., & Harley, C. B. (1992) · Journal of Molecular Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,069
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LGA: a method for finding 3D similarities in protein structures
Zemla, A. (2003) · Nucleic Acids Research
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 1,069
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PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
Chawla, A., Barak, Y., Nagy, L., Liao, D., Tontonoz, P., & Evans, R. M. (2001) · Nature Medicine
Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism
Cited by 1,069
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Roles of heat-shock proteins in innate and adaptive immunity.
Srivastava, P. (2002) · Nature reviews. Immunology
Heat shock proteins researchImmunotherapy and Immune Responses
Cited by 1,069
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HDAC family: What are the cancer relevant targets?
Witt, O., Deubzer, H. E., Milde, T., & Oehme, I. (2009) · Cancer Letters
Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation
Cited by 1,069
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Massively parallel single-nucleus RNA-seq with DroNc-seq
Habib, N., Avraham-Davidi, I., Basu, A., Burks, T., Shekhar, K., Hofree, M., Choudhury, S. R., Aguet, F., Gelfand, E., Ardlie, K., et al. (2017) · Nature Methods
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,069
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Skeletal remodeling in health and disease
Zaidi, M. (2007) · Nature Medicine
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,069
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Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network
Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 1,069
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Exploring the three-dimensional organization of genomes: Interpreting chromatin interaction data
Dekker, J., Marti-Renom, M. A., & Mirny, L. A. (2013) · Nature Reviews Genetics
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 1,068
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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
Lei, K., & Davis, R. J. (2003) · Proceedings of the National Academy of Sciences
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,068
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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer
Gross, M. I., Demo, S. D., Dennison, J. B., Chen, L., Chernov-Rogan, T., Goyal, B., Janes, J. R., Laidig, G. J., Lewis, E. R., Li, J., et al. (2014) · Molecular Cancer Therapeutics
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 1,068
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