Most cited biochemistry, genetics and molecular biology papers
- Verified
Caspases in apoptosis and beyond
Li, J., & Yuan, J. (2008) · Oncogene
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 1,090
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MicroRNA-21 Targets the Tumor Suppressor Gene Tropomyosin 1 (TPM1)
Zhu, S., Si, M.-L., Wu, H., & Mo, Y.-Y. (2007) · Journal of Biological Chemistry
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 1,090
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Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
Powers, J. C., Asgian, J. L., Ekici, Ö. D., & James, K. E. (2002) · Chemical Reviews
Protease and Inhibitor MechanismsEnzyme function and inhibition
Cited by 1,090
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Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1
Delerive, P., De Bosscher, K., Besnard, S., Vanden Berghe, W., Peters, J. M., Gonzalez, F. J., Fruchart, J.-C., Tedgui, A., Haegeman, G., & Staels, B. (1999) · Journal of Biological Chemistry
Peroxisome Proliferator-Activated ReceptorsCytokine Signaling Pathways and Interactions
Cited by 1,089
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Muscle wasting in disease: molecular mechanisms and promising therapies
Cohen, S., Nathan, J. A., & Goldberg, A. L. (2015) · Nature Reviews Drug Discovery
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 1,089
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Regulation of Muscle Fiber Type and Running Endurance by PPARδ
Wang, Y.-X., Zhang, C.-L., Yu, R. T., Cho, H. K., Nelson, M. C., Bayuga-Ocampo, C. R., Ham, J., Kang, H., & Evans, R. M. (2004) · PLoS Biology
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 1,089
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Raman spectroscopy of lipids: A review
Czamara, K., Majzner, K., Pacia, M. Z., Kochan, K., Kaczor, A., & Baranska, M. (2015) · Journal of Raman Spectroscopy
Spectroscopy Techniques in Biomedical and Chemical ResearchMetabolomics and Mass Spectrometry Studies
Cited by 1,089
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Microbiota and neurodevelopmental windows: implications for brain disorders
Borre, Y. E., O’Keeffe, G. W., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2014) · Trends in Molecular Medicine
Gut microbiota and healthInfant Nutrition and Health
Cited by 1,089
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The intestinal microbiota fuelling metabolic inflammation
Tilg, H., Zmora, N., Adolph, T. E., & Elinav, E. (2020) · Nature Reviews Immunology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 1,089
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Substantial biases in ultra-short read data sets from high-throughput DNA sequencing
Dohm, J. C., Lottaz, C., Borodina, T., & Himmelbauer, H. (2008) · Nucleic Acids Research
Genomics and Phylogenetic StudiesFractal and DNA sequence analysis
Cited by 1,088
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Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth
Shao, Y., Forster, S. C., Tsaliki, E., Vervier, K., Strang, A., Simpson, N., Kumar, N., Stares, M. D., Rodger, A., Brocklehurst, P., et al. (2019) · Nature
Gut microbiota and healthInfant Nutrition and Health
Cited by 1,088
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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
Myocardial Infarction Genetics Consortium (2009) · Nature Genetics
Genetic Associations and EpidemiologyAcute Myocardial Infarction Research
Cited by 1,088
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CCTop: An intuitive, flexible and reliable CRISPR/Cas9 target prediction tool
Stemmer, M., Thumberger, T., del Sol Keyer, M., Wittbrodt, J., & Mateo, J. L. (2015) · PLoS ONE
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,088
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mTOR signalling and cellular metabolism are mutual determinants in cancer
Mossmann, D., Park, S., & Hall, M. N. (2018) · Nature reviews. Cancer
PI3K/AKT/mTOR signaling in cancerCancer, Hypoxia, and Metabolism
Cited by 1,088
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Construction of a human cell landscape at single-cell level
Han, X., Zhou, Z., Fei, L., Sun, H., Wang, R., Chen, Y., Chen, H., Wang, J., Tang, H., Ge, W., et al. (2020) · Nature
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,087
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The role of mitochondria in aging
Bratic, A., & Larsson, N.-G. (2013) · Journal of Clinical Investigation
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 1,087
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Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
Cuzzocrea, S., Riley, D. P., Caputi, A. P., & Salvemini, D. (2001) · Pharmacological Reviews
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,087
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The ETS-domain transcription factor family
Sharrocks, A. D. (2001) · Nature Reviews Molecular Cell Biology
Genomics and Chromatin DynamicsGene Regulatory Network Analysis
Cited by 1,086
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Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
Sakai, W., Swisher, E. M., Karlan, B. Y., Agarwal, M. K., Higgins, J., Friedman, C., Villegas, E., Jacquemont, C., Farrugia, D. J., Couch, F. J., et al. (2008) · Nature
BRCA gene mutations in cancerPARP inhibition in cancer therapy
Cited by 1,086
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Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
Kato, M., Patel, M. S., Levasseur, R., Lobov, I., Chang, B. H.-J., Glass, D. A., Hartmann, C., Li, L., Hwang, T.-H., Brayton, C. F., et al. (2002) · The Journal of Cell Biology
Bone Metabolism and DiseasesWnt/β-catenin signaling in development and cancer
Cited by 1,086
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Insect resistance to Bt crops: lessons from the first billion acres
Tabashnik, B. E., Brévault, T., & Carrière, Y. (2013) · Nature Biotechnology
Insect Resistance and GeneticsGenetically Modified Organisms Research
Cited by 1,086
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p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2
Karlseder, J., Broccoli, D., Dai, Y., Hardy, S., & de Lange, T. (1999) · Science
Telomeres, Telomerase, and SenescenceCell death mechanisms and regulation
Cited by 1,086
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YAP/TAZ upstream signals and downstream responses
Totaro, A., Panciera, T., & Piccolo, S. (2018) · Nature Cell Biology
Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions
Cited by 1,086
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Microtubule assembly, organization and dynamics in axons and dendrites
Conde, C., & Cáceres, A. (2009) · Nature Reviews Neuroscience
Microtubule and mitosis dynamicsAxon Guidance and Neuronal Signaling
Cited by 1,086
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