Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability

Rodrigues, C. H., Pires, D. E., & Ascher, D. B. (2018) · Nucleic Acids Research

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,086

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

Kokoszka, J. E., Waymire, K. G., Levy, S. E., Sligh, J. E., Cai, J., Jones, D. P., MacGregor, G. R., & Wallace, D. C. (2004) · Nature

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 1,086

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

Davies, H., Glodzik, D., Morganella, S., Yates, L. R., Staaf, J., Zou, X., Ramakrishna, M., Martin, S., Boyault, S., Sieuwerts, A. M., et al. (2017) · Nature Medicine

BRCA gene mutations in cancerCancer Genomics and Diagnostics

Cited by 1,086

ER stress and diseases

Yoshida, H. (2007) · The FEBS Journal

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 1,086

Confronting false discoveries in single-cell differential expression

Squair, J. W., Gautier, M., Kathe, C., Anderson, M. A., James, N. D., Hutson, T. H., Hudelle, R., Qaiser, T., Matson, K. J. E., Barraud, Q., et al. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 1,086

ATP citrate lyase inhibition can suppress tumor cell growth

Hatzivassiliou, G., Zhao, F., Bauer, D. E., Andreadis, C., Shaw, A. N., Dhanak, D., Hingorani, S. R., Tuveson, D. A., & Thompson, C. B. (2005) · Cancer Cell

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 1,086

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

Wilson, J. E. (2003) · Journal of Experimental Biology

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 1,085

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Toyama, E. Q., Herzig, S., Courchet, J., Lewis, T. L., Losón, O. C., Hellberg, K., Young, N. P., Chen, H., Polleux, F., Chan, D. C., et al. (2016) · Science

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,085

Tumor suppressors and cell metabolism: a recipe for cancer growth

Jones, R. G., & Thompson, C. B. (2009) · Genes & Development

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,085

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Falck, J., Mailand, N., Syljuåsen, R. G., Bartek, J., & Lukas, J. (2001) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,085

Methods of integrating data to uncover genotype-phenotype interactions

Ritchie, M. D., Holzinger, E. R., Li, R., Pendergrass, S. A., & Kim, D. (2015) · Nature Reviews Genetics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 1,085

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

Sanderson, E., Davey Smith, G., Windmeijer, F., & Bowden, J. (2019) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 1,085

Incidence and trends of childhood type 1 diabetes worldwide 1990–1999

The DIAMOND Project Group (2006) · Diabetic Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,085

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

Artandi, S. E., Chang, S., Lee, S.-L., Alson, S., Gottlieb, G. J., Chin, L., & DePinho, R. A. (2000) · Nature

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,085

Pleiotropy in complex traits: challenges and strategies

Solovieff, N., Cotsapas, C., Lee, P. H., Purcell, S. M., & Smoller, J. W. (2013) · Nature Reviews Genetics

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,085

Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

Roach, J. C., Glusman, G., Smit, A. F. A., Huff, C. D., Hubley, R., Shannon, P. T., Rowen, L., Pant, K. P., Goodman, N., Bamshad, M., et al. (2010) · Science

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

Cited by 1,084

Single-cell RNA-seq denoising using a deep count autoencoder

Eraslan, G., Simon, L. M., Mircea, M., Mueller, N. S., & Theis, F. J. (2019) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 1,084

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

Welcker, M., & Clurman, B. E. (2008) · Nature Reviews Cancer

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 1,084

The microcosmos of cancer

Lujambio, A., & Lowe, S. W. (2012) · Nature

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 1,084

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth

Maxwell, P. H., Dachs, G. U., Gleadle, J. M., Nicholls, L. G., Harris, A. L., Stratford, I. J., Hankinson, O., Pugh, C. W., & Ratcliffe, P. J. (1997) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 1,084

The mTOR‐regulated phosphoproteome reveals a mechanism of mTORC1‐mediated inhibition of growth factor signaling

Hsu, P. P., Kang, S. A., Rameseder, J., Zhang, Y., Ottina, K. A., Lim, D., Peterson, T. R., Choi, Y., Gray, N. S., Yaffe, M. B., et al. (2011) · Science

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 1,084

Insect glutathione transferases and insecticide resistance

Enayati, A. A., Ranson, H., & Hemingway, J. (2005) · Insect Molecular Biology

Insect Resistance and GeneticsGlutathione Transferases and Polymorphisms

Cited by 1,084

Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation

Hemarajata, P., & Versalovic, J. (2013) · Therapeutic Advances in Gastroenterology

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 1,083

Illuminating the silence: understanding the structure and function of small RNAs

Rana, T. M. (2007) · Nature Reviews Molecular Cell Biology

RNA Interference and Gene DeliveryPlant Molecular Biology Research

Cited by 1,083