Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery

Burslem, G. M., & Crews, C. M. (2020) · Cell

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 1,079

A novel and universal method for microRNA RT-qPCR data normalization

Mestdagh, P., Van Vlierberghe, P., De Weer, A., Muth, D., Westermann, F., Speleman, F., & Vandesompele, J. (2009) · Genome Biology

Molecular Biology Techniques and ApplicationsMicroRNA in disease regulation

Cited by 1,079

Translational control by 5′-untranslated regions of eukaryotic mRNAs

Hinnebusch, A. G., Ivanov, I. P., & Sonenberg, N. (2016) · Science

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 1,079

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

Apweiler, R. (2001) · Nucleic Acids Research

Genomics and Phylogenetic StudiesMachine Learning in Bioinformatics

Cited by 1,079

Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K. M., Chrzanowska, K. H., Saar, K., Beckmann, G., Seemanová, E., Cooper, P. R., Nowak, N. J., et al. (1998) · Cell

DNA Repair MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 1,079

Increasing complexity of Ras signaling

Campbell, S. L., Khosravi-Far, R., Rossman, K. L., Clark, G. J., & Der, C. J. (1998) · Oncogene

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 1,079

ATM Activation by Oxidative Stress

Guo, Z., Kozlov, S., Lavin, M. F., Person, M. D., & Paull, T. T. (2010) · Science

DNA Repair MechanismsRedox biology and oxidative stress

Cited by 1,079

Insulin antibodies in insulin-dependent diabetics before insulin treatment

Palmer, J. P., Asplin, C. M., Clemons, P., Lyen, K., Tatpati, O., Raghu, P. K., & Paquette, T. L. (1983) · Science

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,078

Codon Optimality Is a Major Determinant of mRNA Stability

Presnyak, V., Alhusaini, N., Chen, Y.-H., Martin, S., Morris, N., Kline, N., Olson, S., Weinberg, D., Baker, K. E., Graveley, B. R., et al. (2015) · Cell

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 1,078

Large language models generate functional protein sequences across diverse families

Madani, A., Krause, B., Greene, E. R., Subramanian, S., Mohr, B. P., Holton, J. M., Olmos, J. L., Xiong, C., Sun, Z. Z., Socher, R., et al. (2023) · Nature Biotechnology

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 1,078

Strategies for silencing human disease using RNA interference

Kim, D. H., & Rossi, J. J. (2007) · Nature Reviews Genetics

RNA Interference and Gene DeliveryRNA regulation and disease

Cited by 1,078

Autophagy mediates the mitotic senescence transition

Young, A. R. J., Narita, M., Ferreira, M., Kirschner, K., Sadaie, M., Darot, J. F. J., Tavaré, S., Arakawa, S., Shimizu, S., Watt, F. M., et al. (2009) · Genes & Development

Autophagy in Disease and TherapyTelomeres, Telomerase, and Senescence

Cited by 1,078

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

Amano, M., Chihara, K., Kimura, K., Fukata, Y., Nakamura, N., Matsuura, Y., & Kaibuchi, K. (1997) · Science

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 1,077

Biological and therapeutic impact of intratumor heterogeneity in cancer evolution

McGranahan, N., & Swanton, C. (2015) · Cancer Cell

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

Cited by 1,077

Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer.

Hu, R., Dunn, T. A., Wei, S., Isharwal, S., Veltri, R. W., Humphreys, E., Han, M., Partin, A. W., Vessella, R. L., Isaacs, W. B., et al. (2009) · Cancer Research

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 1,077

In Search of the In Vivo Identity of Mesenchymal Stem Cells

da Silva Meirelles, L., Caplan, A. I., & Nardi, N. B. (2008) · Stem Cells

Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation

Cited by 1,077

Estimating the pattern of nucleotide substitution

Yang, Z. (1994) · Journal of Molecular Evolution

Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms

Cited by 1,076

Osteocytes, mechanosensing and Wnt signaling

Bonewald, L. F., & Johnson, M. L. (2008) · Bone

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,076

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

Segata, N., Haake, S. K., Mannon, P., Lemon, K. P., Waldron, L., Gevers, D., Huttenhower, C., & Izard, J. (2012) · Genome Biology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,076

Candidate-gene approaches for studying complex genetic traits: practical considerations

Tabor, H. K., Risch, N. J., & Myers, R. M. (2002) · Nature Reviews Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,076

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D., & Rubin, R. A. (2011) · BMC Gastroenterology

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 1,076

Genome Engineering With Zinc-Finger Nucleases

Carroll, D. (2011) · Genetics

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,076

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

Everard, A., Lazarevic, V., Derrien, M., Girard, M., Muccioli, G. G., Neyrinck, A. M., Possemiers, S., Van Holle, A., François, P., de Vos, W. M., et al. (2011) · Diabetes

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 1,076

The “hitchhiking effect” revisited

Kaplan, N. L., Hudson, R. R., & Langley, C. H. (1989) · Genetics

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 1,076