Most cited biochemistry, genetics and molecular biology papers
- Verified
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
Lambeir, A.-M., Durinx, C., Scharpé, S., & De Meester, I. (2003) · Critical Reviews in Clinical Laboratory Sciences
Peptidase Inhibition and AnalysisProtease and Inhibitor Mechanisms
Cited by 955
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Genomic insights into the origin of farming in the ancient Near East
Lazaridis, I., Nadel, D., Rollefson, G., Merrett, D. C., Rohland, N., Mallick, S., Fernandes, D., Novak, M., Gamarra, B., Sirak, K., et al. (2016) · Nature
Forensic and Genetic ResearchArchaeology and ancient environmental studies
Cited by 955
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ROS, mitochondria and the regulation of autophagy
Scherz-Shouval, R., & Elazar, Z. (2007) · Trends in Cell Biology
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 954
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Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
Chinetti, G., Fruchart, J.-C., & Staels, B. (2000) · Inflammation Research
Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health
Cited by 954
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Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell
Kagan, H. M., & Li, W. (2003) · Journal of Cellular Biochemistry
Microbial metabolism and enzyme functionMetal-Catalyzed Oxygenation Mechanisms
Cited by 954
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Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
John, S., Sabo, P. J., Thurman, R. E., Sung, M.-H., Biddie, S. C., Johnson, T. A., Hager, G. L., & Stamatoyannopoulos, J. A. (2011) · Nature Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 954
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The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell
Genomics and Chromatin DynamicsT-cell and B-cell Immunology
Cited by 954
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Calcium-activated potassium channels
Vergara, C., Latorre, R., Marrion, N. V., & Adelman, J. P. (1998) · Current Opinion in Neurobiology
Ion channel regulation and functionCardiac electrophysiology and arrhythmias
Cited by 954
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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
SHEPHERD, P. R., WITHERS, D. J., & SIDDLE, K. (1998) · Biochemical Journal
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 953
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Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning
Greenwald, N. F., Miller, G., Moen, E., Kong, A., Kagel, A., Dougherty, T., Fullaway, C. C., McIntosh, B. J., Leow, K. X., Schwartz, M. S., et al. (2022) · Nature Biotechnology
Cell Image Analysis TechniquesAI in cancer detection
Cited by 953
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The Microbiome and the Respiratory Tract
Dickson, R. P., Erb-Downward, J. R., Martinez, F. J., & Huffnagle, G. B. (2016) · Annual Review of Physiology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 953
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Free radical-induced damage to DNA: mechanisms and measurement
Dizdaroglu, M., Jaruga, P., Birincioglu, M., & Rodriguez, H. (2002) · Free Radical Biology and Medicine
Carcinogens and Genotoxicity AssessmentRedox biology and oxidative stress
Cited by 953
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Mitochondrial Dynamics in Mammalian Health and Disease
Liesa, M., Palacín, M., & Zorzano, A. (2009) · Physiological Reviews
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 953
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Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport
Rosenson, R. S., Brewer, H. B., Davidson, W. S., Fayad, Z. A., Fuster, V., Goldstein, J., Hellerstein, M., Jiang, X.-C., Phillips, M. C., Rader, D. J., et al. (2012) · Circulation
Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health
Cited by 953
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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
Tsai, S. Q., Wyvekens, N., Khayter, C., Foden, J. A., Thapar, V., Reyon, D., Goodwin, M. J., Aryee, M. J., & Joung, J. K. (2014) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 952
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Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
Blangy, A., Lane, H. A., d'Hérin, P., Harper, M., Kress, M., & Niggt, E. A. (1995) · Cell
Microtubule and mitosis dynamicsCancer-related Molecular Pathways
Cited by 952
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Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
Rosenfeld, M. G., Lunyak, V. V., & Glass, C. K. (2006) · Genes & Development
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 952
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Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes
Nunes, S. S., Miklas, J. W., Liu, J., Aschar-Sobbi, R., Xiao, Y., Zhang, B., Jiang, J., Massé, S., Gagliardi, M., Hsieh, A., et al. (2013) · Nature Methods
Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias
Cited by 952
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The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
Xie, Y., Zhu, S., Song, X., Sun, X., Fan, Y., Liu, J., Zhong, M., Yuan, H., Zhang, L., Billiar, T. R., et al. (2017) · Cell Reports
Ferroptosis and cancer prognosisCancer-related Molecular Pathways
Cited by 952
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Protein oxidation and peroxidation
Davies, M. J. (2016) · Biochemical Journal
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 952
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Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma
Annunziata, C. M., Davis, R. E., Demchenko, Y., Bellamy, W., Gabrea, A., Zhan, F., Lenz, G., Hanamura, I., Wright, G., Xiao, W., et al. (2007) · Cancer Cell
NF-κB Signaling PathwaysMultiple Myeloma Research and Treatments
Cited by 952
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Brain-gut-microbe communication in health and disease
Grenham, S., Clarke, G., Cryan, J. F., & Dinan, T. G. (2011) · Frontiers in Physiology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 952
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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
Darnell, J. C., Jensen, K. B., Jin, P., Brown, V., Warren, S. T., & Darnell, R. B. (2001) · Cell
Genetics and Neurodevelopmental DisordersRNA Research and Splicing
Cited by 952
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Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
Salmeen, A., Andersen, J. N., Myers, M. P., Meng, T.-C., Hinks, J. A., Tonks, N. K., & Barford, D. (2003) · Nature
Protein Tyrosine PhosphatasesRedox biology and oxidative stress
Cited by 951
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