Most cited biochemistry, genetics and molecular biology papers
- Verified
Rare Variants of IFIH1 , a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
Nejentsev, S., Walker, N., Riches, D., Egholm, M., & Todd, J. A. (2009) · Science
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 958
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Linking actin dynamics and gene transcription to drive cellular motile functions
Olson, E. N., & Nordheim, A. (2010) · Nature Reviews Molecular Cell Biology
Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling
Cited by 958
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Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain
Lake, B. B., Ai, R., Kaeser, G. E., Salathia, N. S., Yung, Y. C., Liu, R., Wildberg, A., Gao, D., Fung, H.-L., Chen, S., et al. (2016) · Science
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 957
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A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
Saijo, K., Winner, B., Carson, C. T., Collier, J. G., Boyer, L., Rosenfeld, M. G., Gage, F. H., & Glass, C. K. (2009) · Cell
Nuclear Receptors and SignalingNeuroinflammation and Neurodegeneration Mechanisms
Cited by 957
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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Silber, J., Lim, D. A., Petritsch, C., Persson, A. I., Maunakea, A. K., Yu, M., Vandenberg, S. R., Ginzinger, D. G., James, C. D., Costello, J. F., et al. (2008) · BMC Medicine
MicroRNA in disease regulationGlioma Diagnosis and Treatment
Cited by 957
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Automatic measurement of sister chromatid exchange frequency.
Zack, G. W., Rogers, W. E., & Latt, S. A. (1977) · Journal of Histochemistry & Cytochemistry
Cell Image Analysis TechniquesCarcinogens and Genotoxicity Assessment
Cited by 957
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MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
Najafi-Shoushtari, S. H., Kristo, F., Li, Y., Shioda, T., Cohen, D. E., Gerszten, R. E., & Näär, A. M. (2010) · Science
Cholesterol and Lipid MetabolismMicroRNA in disease regulation
Cited by 957
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Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy
Evans, C. L., Potma, E. O., Puoris'haag, M., Côté, D., Lin, C. P., & Xie, X. S. (2005) · Proceedings of the National Academy of Sciences
Spectroscopy Techniques in Biomedical and Chemical ResearchOptical Imaging and Spectroscopy Techniques
Cited by 957
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Mitochondria take center stage in aging and neurodegeneration
Beal, M. F. (2005) · Annals of Neurology
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 957
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The Fas Signaling Pathway: More Than a Paradigm
Wajant, H. (2002) · Science
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 957
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Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation
Atarashi, K., Suda, W., Luo, C., Kawaguchi, T., Motoo, I., Narushima, S., Kiguchi, Y., Yasuma, K., Watanabe, E., Tanoue, T., et al. (2017) · Science
Gut microbiota and healthInflammatory Bowel Disease
Cited by 957
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
De Jager, P. L., Srivastava, G., Lunnon, K., Burgess, J., Schalkwyk, L. C., Yu, L., Eaton, M. L., Keenan, B. T., Ernst, J., McCabe, C., et al. (2014) · Nature Neuroscience
Epigenetics and DNA MethylationDementia and Cognitive Impairment Research
Cited by 956
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Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
Qiu, P., Simonds, E. F., Bendall, S. C., Gibbs, K. D., Bruggner, R. V., Linderman, M. D., Sachs, K., Nolan, G. P., & Plevritis, S. K. (2011) · Nature Biotechnology
Single-cell and spatial transcriptomicsCell Image Analysis Techniques
Cited by 956
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Interactions Between Human Mesenchymal Stem Cells and Natural Killer Cells
Sotiropoulou, P. A., Perez, S. A., Gritzapis, A. D., Baxevanis, C. N., & Papamichail, M. (2006) · Stem Cells
Mesenchymal stem cell researchImmune Cell Function and Interaction
Cited by 956
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A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
Grubman, A., Chew, G., Ouyang, J. F., Sun, G., Choo, X. Y., McLean, C., Simmons, R. K., Buckberry, S., Vargas-Landin, D. B., Poppe, D., et al. (2019) · Nature Neuroscience
Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments
Cited by 956
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The tubulin code and its role in controlling microtubule properties and functions
Janke, C., & Magiera, M. M. (2020) · Nature Reviews Molecular Cell Biology
Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases
Cited by 956
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HMGB1 in health and disease
Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine
Advanced Glycation End Products researchImmune Response and Inflammation
Cited by 956
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Regulation of endoplasmic reticulum turnover by selective autophagy
Khaminets, A., Heinrich, T., Mari, M., Grumati, P., Huebner, A. K., Akutsu, M., Liebmann, L., Stolz, A., Nietzsche, S., Koch, N., et al. (2015) · Nature
Autophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease
Cited by 956
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Dynamic molecular processes mediate cellular mechanotransduction
Hoffman, B. D., Grashoff, C., & Schwartz, M. A. (2011) · Nature
Cellular Mechanics and InteractionsForce Microscopy Techniques and Applications
Cited by 956
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Epigenetic mechanisms of longevity and aging
Sen, P., Shah, P. P., Nativio, R., & Berger, S. L. (2016) · Cell
Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation
Cited by 956
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MYC as a regulator of ribosome biogenesis and protein synthesis
van Riggelen, J., Yetil, A., & Felsher, D. W. (2010) · Nature Reviews Cancer
RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 956
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Recommendations for Follow-up Care of Individuals With an Inherited Predisposition to Cancer: II. BRCA1 and BRCA2
Burke, W. (1997) · JAMA
BRCA gene mutations in cancerMultiple and Secondary Primary Cancers
Cited by 955
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An Introduction to Systems Biology: Design Principles of Biological Circuits
Alon, U. (2019) · Chapman & Hall/CRC eBooks
Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction
Cited by 955
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Immune responses to AAV vectors: overcoming barriers to successful gene therapy
Mingozzi, F., & High, K. A. (2013) · Blood
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 955
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