Most cited biochemistry, genetics and molecular biology papers
- Verified
PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
Xie, H., Cui, Z., Wang, L., Xia, Z., Hu, Y., Xian, L., Li, C., Xie, L., Crane, J., Wan, M., et al. (2014) · Nature Medicine
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 951
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ATR disruption leads to chromosomal fragmentation and early embryonic lethality
Brown, E. J., & Baltimore, D. (2000) · Genes & Development
DNA Repair MechanismsDevelopmental Biology and Gene Regulation
Cited by 951
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Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE
Mavaddat, N., Peock, S., Frost, D., Ellis, S., Platte, R., Fineberg, E., Evans, D. G., Izatt, L., Eeles, R. A., Adlard, J., et al. (2013) · JNCI: Journal of the National Cancer Institute
BRCA gene mutations in cancerMultiple and Secondary Primary Cancers
Cited by 951
- VerifiedRetracted
RETRACTED ARTICLE: Culture of previously uncultured members of the human gut microbiota by culturomics
Lagier, J.-C., Khelaifia, S., Alou, M. T., Ndongo, S., Dione, N., Hugon, P., Caputo, A., Cadoret, F., Traore, S. I., Seck, E. H., et al. (2016) · Nature Microbiology
Gut microbiota and healthBacterial Identification and Susceptibility Testing
Cited by 951
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Endogenous HMGB1 regulates autophagy
Tang, D., Kang, R., Livesey, K. M., Cheh, C.-W., Farkas, A., Loughran, P., Hoppe, G., Bianchi, M. E., Tracey, K. J., Zeh, H. J., et al. (2010) · Journal of Cell Biology
Autophagy in Disease and TherapyAdvanced Glycation End Products research
Cited by 951
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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Yin, H., Xue, W., Chen, S., Bogorad, R. L., Benedetti, E., Grompe, M., Koteliansky, V., Sharp, P. A., Jacks, T., & Anderson, D. G. (2014) · Nature Biotechnology
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 951
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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
Paquet, D., Kwart, D., Chen, A., Sproul, A., Jacob, S., Teo, S., Olsen, K. M., Gregg, A., Noggle, S., & Tessier-Lavigne, M. (2016) · Nature
CRISPR and Genetic EngineeringPluripotent Stem Cells Research
Cited by 951
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Causal associations between risk factors and common diseases inferred from GWAS summary data
Zhu, Z., Zheng, Z., Zhang, F., Wu, Y., Trzaskowski, M., Maier, R., Robinson, M. R., McGrath, J. J., Visscher, P. M., Wray, N. R., et al. (2018) · Nature Communications
Genetic Associations and EpidemiologyGenetics and Physical Performance
Cited by 951
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The age of cancer
DePinho, R. A. (2000) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 951
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S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death
Gu, Z., Kaul, M., Yan, B., Kridel, S. J., Cui, J., Strongin, A., Smith, J. W., Liddington, R. C., & Lipton, S. A. (2002) · Science
Protease and Inhibitor MechanismsRedox biology and oxidative stress
Cited by 950
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Host lifestyle affects human microbiota on daily timescales
David, L. A., Materna, A. C., Friedman, J., Campos-Baptista, M. I., Blackburn, M. C., Perrotta, A., Erdman, S. E., & Alm, E. J. (2014) · Genome biology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 950
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Structural Symmetry and Protein Function
Goodsell, D. S., & Olson, A. J. (2000) · Annual Review of Biophysics and Biomolecular Structure
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 950
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Mitochondrial dysfunction and oxidative stress in heart disease
Peoples, J. N., Saraf, A., Ghazal, N., Pham, T. T., & Kwong, J. Q. (2019) · Experimental & Molecular Medicine
Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion
Cited by 950
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Notch signaling: simplicity in design, versatility in function
Andersson, E. R., Sandberg, R., & Lendahl, U. (2011) · Development
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 950
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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
Kruidenier, L., Chung, C.-W., Cheng, Z., Liddle, J., Che, K., Joberty, G., Bantscheff, M., Bountra, C., Bridges, A., Diallo, H., et al. (2012) · Nature
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 950
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The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit
Brodersen, D. E., Clemons, W. M., Carter, A. P., Morgan-Warren, R. J., Wimberly, B. T., & Ramakrishnan, V. (2000) · Cell
RNA and protein synthesis mechanismsMicrobial Natural Products and Biosynthesis
Cited by 950
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The nature of nurture: Effects of parental genotypes
Kong, A., Thorleifsson, G., Frigge, M. L., Vilhjalmsson, B. J., Young, A. I., Thorgeirsson, T. E., Benonisdottir, S., Oddsson, A., Halldorsson, B. V., Masson, G., et al. (2018) · Science
Genetic Associations and EpidemiologyIntergenerational and Educational Inequality Studies
Cited by 949
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Genome evolution in the allotetraploid frog Xenopus laevis
Session, A. M., Uno, Y., Kwon, T., Chapman, J. A., Toyoda, A., Takahashi, S., Fukui, A., Hikosaka, A., Suzuki, A., Kondo, M., et al. (2016) · Nature
Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies
Cited by 949
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Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses
Kaplan, J. B. (2010) · Journal of Dental Research
Bacterial biofilms and quorum sensingEscherichia coli research studies
Cited by 949
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A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
Araki, N., Johnson, M. T., & Swanson, J. A. (1996) · The Journal of cell biology
Cellular transport and secretionPI3K/AKT/mTOR signaling in cancer
Cited by 949
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Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
Leppek, K., Das, R., & Barna, M. (2018) · Nature Reviews Molecular Cell Biology
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 949
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Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease
Chen, W.-T., Lu, A., Craessaerts, K., Pavie, B., Sala Frigerio, C., Corthout, N., Qian, X., Laláková, J., Kühnemund, M., Voytyuk, I., et al. (2020) · Cell
Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments
Cited by 949
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Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement
Goodarzi, H., Liu, X., Nguyen, H. C. B., Zhang, S., Fish, L., & Tavazoie, S. F. (2015) · Cell
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 949
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Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation
de La Serre, C. B., Ellis, C. L., Lee, J., Hartman, A. L., Rutledge, J. C., & Raybould, H. E. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 949
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