Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Gottlob, K., Majewski, N., Kennedy, S., Kandel, E., Robey, R. B., & Hay, N. (2001) · Genes & Development

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 961

Sodium and calcium channels in bovine chromaffin cells

Fenwick, E. M., Marty, A., & Neher, E. (1982) · The Journal of Physiology

Ion channel regulation and functionCardiac electrophysiology and arrhythmias

Cited by 961

Synaptotagmin I functions as a calcium regulator of release probability

Fernández-Chacón, R., Königstorfer, A., Gerber, S. H., García, J., Matos, M. F., Stevens, C. F., Brose, N., Rizo, J., Rosenmund, C., & Südhof, T. C. (2001) · Nature

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 961

Targeted protein degradation: expanding the toolbox

Schapira, M., Calabrese, M. F., Bullock, A. N., & Crews, C. M. (2019) · Nature Reviews Drug Discovery

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 960

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

Vulliamy, T., Marrone, A., Goldman, F., Dearlove, A., Bessler, M., Mason, P. J., & Dokal, I. (2001) · Nature

Telomeres, Telomerase, and SenescenceBlood disorders and treatments

Cited by 960

Recurrent R-spondin fusions in colon cancer

Seshagiri, S., Stawiski, E. W., Durinck, S., Modrusan, Z., Storm, E. E., Conboy, C. B., Chaudhuri, S., Guan, Y., Janakiraman, V., Jaiswal, B. S., et al. (2012) · Nature

Cancer Genomics and DiagnosticsGenetic factors in colorectal cancer

Cited by 960

Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling

Levy, M., Thaiss, C. A., Zeevi, D., Dohnalová, L., Zilberman-Schapira, G., Mahdi, J. A., David, E., Savidor, A., Korem, T., Herzig, Y., et al. (2015) · Cell

Gut microbiota and healthInflammasome and immune disorders

Cited by 960

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

Caesar, R., Tremaroli, V., Kovatcheva-Datchary, P., Cani, P. D., & Bäckhed, F. (2015) · Cell Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 960

Mitochondria in the Regulation of Innate and Adaptive Immunity

Weinberg, S. E., Sena, L. A., & Chandel, N. S. (2015) · Immunity

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 960

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

van Rooij, E., Quiat, D., Johnson, B. A., Sutherland, L. B., Qi, X., Richardson, J. A., Kelm, R. J., & Olson, E. N. (2009) · Developmental Cell

Muscle Physiology and DisordersMicroRNA in disease regulation

Cited by 960

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

Huttlin, E. L., Bruckner, R. J., Navarrete-Perea, J., Cannon, J. R., Baltier, K., Gebreab, F., Gygi, M. P., Thornock, A., Zarraga, G., Tam, S., et al. (2020) · Cell

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 960

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

Matsusaka, T., Fujikawa, K., Nishio, Y., Mukaida, N., Matsushima, K., Kishimoto, T., & Akira, S. (1993) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 959

The role of bacterial cell wall hydrophobicity in adhesion

van Loosdrecht, M. C., Lyklema, J., Norde, W., Schraa, G., & Zehnder, A. J. (1987) · Applied and Environmental Microbiology

Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology

Cited by 959

Regulation of mammalian nucleotide metabolism and biosynthesis

Lane, A. N., & Fan, T. W.-M. (2015) · Nucleic Acids Research

Biochemical and Molecular ResearchCancer and biochemical research

Cited by 959

The genetic history of Ice Age Europe

Fu, Q., Posth, C., Hajdinjak, M., Petr, M., Mallick, S., Fernandes, D., Furtwängler, A., Haak, W., Meyer, M., Mittnik, A., et al. (2016) · Nature

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 959

Source of Estrogen Production in Postmenopausal Women1

GRODIN, J. M., SIITERI, P. K., & MACDONALD, P. C. (1973) · The Journal of Clinical Endocrinology & Metabolism

Estrogen and related hormone effectsMenopause: Health Impacts and Treatments

Cited by 959

Akt regulates growth by directly phosphorylating Tsc2

Potter, C. J., Pedraza, L. G., & Xu, T. (2002) · Nature Cell Biology

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 959

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)

Nishino, I., Fu, J., Tanji, K., Yamada, T., Shimojo, S., Koori, T., Mora, M., Riggs, J. E., Oh, S. J., Koga, Y., et al. (2000) · Nature

Glycogen Storage Diseases and MyoclonusLysosomal Storage Disorders Research

Cited by 959

Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review

Merker, J. D., Oxnard, G. R., Compton, C., Diehn, M., Hurley, P., Lazar, A. J., Lindeman, N., Lockwood, C. M., Rai, A. J., Schilsky, R. L., et al. (2018) · Journal of Clinical Oncology

Cancer Genomics and DiagnosticsBRCA gene mutations in cancer

Cited by 959

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Guo, Y., Xu, Q., Canzio, D., Shou, J., Li, J., Gorkin, D. U., Jung, I., Wu, H., Zhai, Y., Tang, Y., et al. (2015) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 958

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Isaacs, J. S., Jung, Y. J., Mole, D. R., Lee, S., Torres-Cabala, C., Chung, Y.-L., Merino, M., Trepel, J., Zbar, B., Toro, J., et al. (2005) · Cancer Cell

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 958

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A. D., Rhemtulla, M., de Vlaming, R., Ritchie, S. J., Mallard, T. T., Hill, W. D., Ip, H. F., Marioni, R. E., McIntosh, A. M., Deary, I. J., et al. (2019) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 958

Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin

Anderl, J. N., Franklin, M. J., & Stewart, P. S. (2000) · Antimicrobial Agents and Chemotherapy

Bacterial biofilms and quorum sensingAntibiotic Resistance in Bacteria

Cited by 958

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

Monaco, G., Lee, B., Xu, W., Mustafah, S., Hwang, Y. Y., Carré, C., Burdin, N., Visan, L., Ceccarelli, M., Poidinger, M., et al. (2019) · Cell Reports

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 958