Most cited biochemistry, genetics and molecular biology papers
- Verified
Clinical use of lentiviral vectors
Milone, M. C., & O’Doherty, U. (2018) · Leukemia
Virus-based gene therapy researchCAR-T cell therapy research
Cited by 930
- Verified
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
Semenza, G. L. (2001) · Trends in Molecular Medicine
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 930
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The sympathetic nervous system induces a metastatic switch in primary breast cancer
Sloan, E. K., Priceman, S. J., Cox, B. F., Yu, S., Pimentel, M. A., Tangkanangnukul, V., Arevalo, J. M. G., Morizono, K., Karanikolas, B. D. W., Wu, L., et al. (2010) · Cancer Research
Cancer, Stress, Anesthesia, and Immune ResponseImmune cells in cancer
Cited by 930
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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
Sinclair, L. V., Rolf, J., Emslie, E., Shi, Y.-B., Taylor, P. M., & Cantrell, D. A. (2013) · Nature Immunology
Amino Acid Enzymes and MetabolismT-cell and B-cell Immunology
Cited by 930
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Metabolic dependencies drive species co-occurrence in diverse microbial communities
Zelezniak, A., Andrejev, S., Ponomarova, O., Mende, D. R., Bork, P., & Patil, K. R. (2015) · Proceedings of the National Academy of Sciences
Microbial Metabolic Engineering and BioproductionMicrobial Community Ecology and Physiology
Cited by 930
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Insulin resistance: review of the underlying molecular mechanisms
Yaribeygi, H., Farrokhi, F. R., Butler, A. E., & Sahebkar, A. (2019) · Journal of Cellular Physiology
Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases
Cited by 929
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Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons
Armstrong, C. M. (1971) · The Journal of General Physiology
Ion channel regulation and functionIon Transport and Channel Regulation
Cited by 929
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Enhancer function: new insights into the regulation of tissue-specific gene expression
Ong, C.-T., & Corces, V. G. (2011) · Nature Reviews Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 929
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American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants
Kearney, H. M., Thorland, E. C., Brown, K. K., Quintero-Rivera, F., & South, S. T. (2011) · Genetics in Medicine
Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases
Cited by 929
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Targeting Autophagy in Cancer: Recent Advances and Future Directions
Amaravadi, R. K., Kimmelman, A. C., & Debnath, J. (2019) · Cancer Discovery
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 928
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Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
Urlinger, S., Baron, U., Thellmann, M., Hasan, M. T., Bujard, H., & Hillen, W. (2000) · Proceedings of the National Academy of Sciences
Bacterial Genetics and BiotechnologyGene Regulatory Network Analysis
Cited by 928
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The origins, patterns and implications of human spontaneous mutation
Crow, J. F. (2000) · Nature Reviews Genetics
Evolution and Genetic DynamicsGenomics and Rare Diseases
Cited by 928
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An inhibitor of oxidative phosphorylation exploits cancer vulnerability
Molina, J. R., Sun, Y., Protopopova, M., Gera, S., Bandi, M., Bristow, C., McAfoos, T., Morlacchi, P., Ackroyd, J., Agip, A.-N. A., et al. (2018) · Nature Medicine
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 928
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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
Joberty, G., Petersen, C., Gao, L., & Macara, I. G. (2000) · Nature Cell Biology
Protein Kinase Regulation and GTPase SignalingDevelopmental Biology and Gene Regulation
Cited by 928
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Inflammatory mediators in the elderly
Krabbe, K. S., Pedersen, M., & Bruunsgaard, H. (2004) · Experimental Gerontology
Genetics, Aging, and Longevity in Model OrganismsAdipokines, Inflammation, and Metabolic Diseases
Cited by 928
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Mechanism of regulation of the hypoxia‐inducible factor‐1α by the von Hippel‐Lindau tumor suppressor protein
Tanimoto, K., Makino, Y., Pereira, T., & Poellinger, L. (2000) · The EMBO Journal
Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways
Cited by 928
- Verified
Architecture of succinate dehydrogenase and reactive oxygen species generation
Yankovskaya, V., Horsefield, R., Törnroth, S., Luna-Chavez, C., Miyoshi, H., Léger, C., Byrne, B., Cecchini, G., & Iwata, S. (2003) · Science
Enzyme Structure and FunctionMitochondrial Function and Pathology
Cited by 927
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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
Zhao, H., Yang, L., Baddour, J., Achreja, A., Bernard, V., Moss, T., Marini, J. C., Tudawe, T., Seviour, E. G., San Lucas, F. A., et al. (2016) · eLife
Extracellular vesicles in diseaseCancer, Hypoxia, and Metabolism
Cited by 927
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The ectonucleotidases CD 39 and CD 73: Novel checkpoint inhibitor targets
Allard, B., Longhi, M. S., Robson, S. C., & Stagg, J. (2017) · Immunological Reviews
Adenosine and Purinergic SignalingBiochemical and Molecular Research
Cited by 927
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Mammalian genes are transcribed with widely different bursting kinetics
Suter, D. M., Molina, N., Gatfield, D., Schneider, K., Schibler, U., & Naef, F. (2011) · Science
Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics
Cited by 927
- Verified
Energetics of bacterial growth: balance of anabolic and catabolic reactions
Russell, J. B., & Cook, G. M. (1995) · Microbiological Reviews
Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction
Cited by 927
- Verified
Drugging the ‘undruggable’ cancer targets
Dang, C. V., Reddy, E. P., Shokat, K. M., & Soucek, L. (2017) · Nature Reviews Cancer
Protein Kinase Regulation and GTPase SignalingProtein Degradation and Inhibitors
Cited by 927
- Verified
Overcoming Endocrine Resistance in Breast Cancer
Hanker, A. B., Sudhan, D. R., & Arteaga, C. L. (2020) · Cancer Cell
Estrogen and related hormone effectsAdvanced Breast Cancer Therapies
Cited by 927
- Verified
A mechanism converting psychosocial stress into mononuclear cell activation
Bierhaus, A., Wolf, J., Andrassy, M., Rohleder, N., Humpert, P. M., Petrov, D., Ferstl, R., von Eynatten, M., Wendt, T., Rudofsky, G., et al. (2003) · Proceedings of the National Academy of Sciences
NF-κB Signaling PathwaysStress Responses and Cortisol
Cited by 927
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