Most cited biochemistry, genetics and molecular biology papers
- Verified
Tissue-specific mutation accumulation in human adult stem cells during life
Blokzijl, F., de Ligt, J., Jager, M., Sasselli, V., Roerink, S., Sasaki, N., Huch, M., Boymans, S., Kuijk, E., Prins, P., et al. (2016) · Nature
Cancer Genomics and DiagnosticsGenetic factors in colorectal cancer
Cited by 935
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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
Sheedy, F. J., Grebe, A., Rayner, K. J., Kalantari, P., Ramkhelawon, B., Carpenter, S. B., Becker, C. E., Ediriweera, H. N., Mullick, A. E., Golenbock, D. T., et al. (2013) · Nature Immunology
Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases
Cited by 935
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Inflammasomes and Their Roles in Health and Disease
Lamkanfi, M., & Dixit, V. M. (2012) · Annual Review of Cell and Developmental Biology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 935
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ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis -Acting Element Responsible for the Mammalian Unfolded Protein Response
Yoshida, H., Okada, T., Haze, K., Yanagi, H., Yura, T., Negishi, M., & Mori, K. (2000) · Molecular and Cellular Biology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 934
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Secretory Granule Exocytosis
Burgoyne, R. D., & Morgan, A. (2003) · Physiological Reviews
Cellular transport and secretionExtracellular vesicles in disease
Cited by 934
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Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling
Ida, T., Sawa, T., Ihara, H., Tsuchiya, Y., Watanabe, Y., Kumagai, Y., Suematsu, M., Motohashi, H., Fujii, S., Matsunaga, T., et al. (2014) · Proceedings of the National Academy of Sciences
Sulfur Compounds in BiologyRedox biology and oxidative stress
Cited by 934
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In situ sequencing for RNA analysis in preserved tissue and cells
Ke, R., Mignardi, M., Pacureanu, A., Svedlund, J., Botling, J., Wählby, C., & Nilsson, M. (2013) · Nature Methods
Single-cell and spatial transcriptomicsMolecular Biology Techniques and Applications
Cited by 934
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ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells
Snezhkina, A. V., Kudryavtseva, A. V., Kardymon, O. L., Savvateeva, M. V., Melnikova, N. V., Krasnov, G. S., & Dmitriev, A. A. (2019) · Oxidative Medicine and Cellular Longevity
Redox biology and oxidative stressCancer and biochemical research
Cited by 934
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Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k
Jefferies, H. B. J., Fumagalli, S., Dennis, P. B., Reinhard, C., Pearson, R. B., & Thomas, G. (1997) · The EMBO Journal
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 934
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A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
De Santa, F., Barozzi, I., Mietton, F., Ghisletti, S., Polletti, S., Tusi, B. K., Muller, H., Ragoussis, J., Wei, C.-L., & Natoli, G. (2010) · PLoS Biology
Genomics and Chromatin DynamicsCancer-related molecular mechanisms research
Cited by 934
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Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
Geurts, A. M., Cost, G. J., Freyvert, Y., Zeitler, B., Miller, J. C., Choi, V. M., Jenkins, S. S., Wood, A., Cui, X., Meng, X., et al. (2009) · Science
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 934
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De novo mutations in histone-modifying genes in congenital heart disease
Zaidi, S., Choi, M., Wakimoto, H., Ma, L., Jiang, J., Overton, J. D., Romano-Adesman, A., Bjornson, R. D., Breitbart, R. E., Brown, K. K., et al. (2013) · Nature
Congenital heart defects researchGenomics and Rare Diseases
Cited by 934
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The logic of the 26S proteasome.
Collins, G. A., & Goldberg, A. L. (2017) · Cell
Ubiquitin and proteasome pathwaysHeat shock proteins research
Cited by 933
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Phospholipase A2 structure/function, mechanism, and signaling
Burke, J. E., & Dennis, E. A. (2009) · Journal of Lipid Research
Lipid metabolism and biosynthesisSphingolipid Metabolism and Signaling
Cited by 933
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The origin of new genes: Glimpses from the young and old
Long, M., Betrán, E., Thornton, K., & Wang, W. (2003) · Nature Reviews Genetics
Chromosomal and Genetic VariationsEvolution and Genetic Dynamics
Cited by 933
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Splanchnic lipolysis in human obesity
Nielsen, S., Guo, Z., Johnson, C. M., Hensrud, D. D., & Jensen, M. D. (2004) · Journal of Clinical Investigation
Lipid metabolism and biosynthesisAdipokines, Inflammation, and Metabolic Diseases
Cited by 933
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Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs
Xia, T., Kovochich, M., Liong, M., Meng, H., Kabehie, S., George, S., Zink, J. I., & Nel, A. E. (2009) · ACS Nano
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 933
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Enterobactin: an archetype for microbial iron transport.
Raymond, K. N., Dertz, E. A., & Kim, S. S. (2003) · Proceedings of the National Academy of Sciences
Bacterial Genetics and BiotechnologyMicrobial Natural Products and Biosynthesis
Cited by 933
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Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis
Gaengel, K., Genové, G., Armulik, A., & Betsholtz, C. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology
Angiogenesis and VEGF in CancerBarrier Structure and Function Studies
Cited by 933
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Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
Dowling, R. J. O., Zakikhani, M., Fantus, I. G., Pollak, M., & Sonenberg, N. (2007) · Cancer Research
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 933
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The proton sponge: a trick to enter cells the viruses did not exploit
Behr, J.-P. (1997) · CHIMIA
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 933
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Increased Cancer-Related Mortality for Patients With Type 2 Diabetes Who Use Sulfonylureas or Insulin
Bowker, S. L., Majumdar, S. R., Veugelers, P., & Johnson, J. A. (2006) · Diabetes Care
Metabolism, Diabetes, and CancerDiabetes Treatment and Management
Cited by 933
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Structure and function of ER membrane contact sites with other organelles
Phillips, M. J., & Voeltz, G. K. (2016) · Nature Reviews Molecular Cell Biology
Cellular transport and secretionIon Channels and Receptors
Cited by 933
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The intestinal epithelium: central coordinator of mucosal immunity
Allaire, J. M., Crowley, S. M., Law, H. T., Chang, S.-Y., Ko, H.-J., & Vallance, B. A. (2018) · Trends in Immunology
Gut microbiota and healthImmune Response and Inflammation
Cited by 933
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