Most cited biochemistry, genetics and molecular biology papers
- Verified
Sparse whole-genome sequencing identifies two loci for major depressive disorder
CONVERGE consortium, Cai, N., Bigdeli, T. B., Kretzschmar, W., Li, Y., Liang, J., Song, L., Hu, J., Li, Q., Jin, W., et al. (2015) · Nature
Genetic Associations and EpidemiologyTreatment of Major Depression
Cited by 864
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Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.
Ahmed, M. U., Thorpe, S. R., & Baynes, J. W. (1986) · Journal of Biological Chemistry
Advanced Glycation End Products researchPotato Plant Research
Cited by 864
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Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
Huang, P., He, Z., Ji, S., Sun, H., Xiang, D., Liu, C., Hu, Y., Wang, X., & Hui, L. (2011) · Nature
Pluripotent Stem Cells ResearchLiver physiology and pathology
Cited by 864
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Transcriptional regulation by Polycomb group proteins
Di Croce, L., & Helin, K. (2013) · Nature Structural & Molecular Biology
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 864
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CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
Dever, D. P., Bak, R. O., Reinisch, A., Camarena, J., Washington, G., Nicolas, C. E., Pavel-Dinu, M., Saxena, N., Wilkens, A. B., Mantri, S., et al. (2016) · Nature
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 864
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Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
Keller, J. N., Kindy, M. S., Holtsberg, F. W., St. Clair, D. K., Yen, H.-C., Germeyer, A., Steiner, S. M., Bruce-Keller, A. J., Hutchins, J. B., & Mattson, M. P. (1998) · The Journal of Neuroscience
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 863
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Autophagy-Independent Functions of the Autophagy Machinery
Galluzzi, L., & Green, D. R. (2019) · Cell
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 863
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DNA loop extrusion by human cohesin
Davidson, I. F., Bauer, B., Goetz, D., Tang, W., Wutz, G., & Peters, J.-M. (2019) · Science
Genomics and Chromatin DynamicsDNA Repair Mechanisms
Cited by 863
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Role of BAX in the Apoptotic Response to Anticancer Agents
Zhang, L., Yu, J., Park, B. H., Kinzler, K. W., & Vogelstein, B. (2000) · Science
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 863
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Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
Krönke, J., Fink, E. C., Hollenbach, P. W., MacBeth, K. J., Hurst, S. N., Udeshi, N. D., Chamberlain, P. P., Mani, D. R., Man, H. W., Gandhi, A. K., et al. (2015) · Nature
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 863
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Integrative clinical genomics of metastatic cancer
Robinson, D. R., Wu, Y.-M., Lonigro, R. J., Vats, P., Cobain, E., Everett, J., Cao, X., Rabban, E., Kumar-Sinha, C., Raymond, V., et al. (2017) · Nature
Cancer Genomics and DiagnosticsGenomics and Rare Diseases
Cited by 863
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Persistent inhibition of cell respiration by nitric oxide: Crucial role of S -nitrosylation of mitochondrial complex I and protective action of glutathione
Clementi, E., Brown, G. C., Feelisch, M., & Moncada, S. (1998) · Proceedings of the National Academy of Sciences
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 863
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Unmasking senescence: context-dependent effects of SASP in cancer
Faget, D. V., Ren, Q., & Stewart, S. A. (2019) · Nature Reviews Cancer
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 863
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Correlated mutations and residue contacts in proteins
Göbel, U., Sander, C., Schneider, R., & Valencia, A. (1994) · Proteins Structure Function and Bioinformatics
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 863
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Common variants associated with plasma triglycerides and risk for coronary artery disease
Do, R., Willer, C. J., Schmidt, E. M., Sengupta, S., Gao, C., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., et al. (2013) · Nature Genetics
Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health
Cited by 862
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Growth, efficiency, and yield of commercial broilers from 1957, 1978, and 2005
Zuidhof, M. J., Schneider, B. L., Carney, V. L., Korver, D. R., & Robinson, F. E. (2014) · Poultry Science
Genetic and phenotypic traits in livestockAnimal Nutrition and Physiology
Cited by 862
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A new pathway for mitochondrial quality control: Mitochondrial-derived vesicles
Sugiura, A., McLelland, G., Fon, E. A., & McBride, H. M. (2014) · The EMBO Journal
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 862
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Autophagy in inflammation, infection, and immunometabolism
Deretic, V. (2021) · Immunity
Autophagy in Disease and TherapyImmune Response and Inflammation
Cited by 862
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Multiple-laboratory comparison of microarray platforms
Irizarry, R. A., Warren, D., Spencer, F., Kim, I. F., Biswal, S., Frank, B. C., Gabrielson, E., Garcia, J. G. N., Geoghegan, J., Germino, G., et al. (2005) · Nature Methods
Gene expression and cancer classificationMolecular Biology Techniques and Applications
Cited by 862
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Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
Malavasi, F., Deaglio, S., Funaro, A., Ferrero, E., Horenstein, A. L., Ortolan, E., Vaisitti, T., & Aydin, S. (2008) · Physiological Reviews
Calcium signaling and nucleotide metabolismBiochemical and Molecular Research
Cited by 862
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The BRCT Domain Is a Phospho-Protein Binding Domain
Yu, X., Chini, C. C. S., He, M., Mer, G., & Chen, J. (2003) · Science
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 862
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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
Hu, W., Zhang, C., Wu, R., Sun, Y., Levine, A., & Feng, Z. (2010) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Cited by 862
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Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
Lithgow, G. J., White, T. M., Melov, S., & Johnson, T. E. (1995) · Proceedings of the National Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsPhysiological and biochemical adaptations
Cited by 862
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The proteasome: overview of structure and functions
TANAKA, K. (2009) · Proceedings of the Japan Academy, Series B
Ubiquitin and proteasome pathwaysHeat shock proteins research
Cited by 862
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