Most cited biochemistry, genetics and molecular biology papers
- Verified
RNA-Targeted Therapeutics
Crooke, S. T., Witztum, J. L., Bennett, C. F., & Baker, B. F. (2018) · Cell Metabolism
RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry
Cited by 841
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Efficient multivariate linear mixed model algorithms for genome-wide association studies
Zhou, X., & Stephens, M. (2014) · Nature Methods
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 841
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Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
Tian, L., Goldstein, A., Wang, H., Ching Lo, H., Sun Kim, I., Welte, T., Sheng, K., Dobrolecki, L. E., Zhang, X., Putluri, N., et al. (2017) · Nature
Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers
Cited by 841
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Superoxide accelerates DNA damage by elevating free-iron levels
Keyer, K., & Imlay, J. A. (1996) · Proceedings of the National Academy of Sciences
Redox biology and oxidative stressMetal-Catalyzed Oxygenation Mechanisms
Cited by 841
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A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival
Singh, A., Greninger, P., Rhodes, D., Koopman, L., Violette, S., Bardeesy, N., & Settleman, J. (2009) · Cancer Cell
Protein Kinase Regulation and GTPase SignalingCancer Cells and Metastasis
Cited by 841
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Neuronal cell-type classification: challenges, opportunities and the path forward
Zeng, H., & Sanes, J. R. (2017) · Nature Reviews Neuroscience
Single-cell and spatial transcriptomicsCell Image Analysis Techniques
Cited by 841
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Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli
Blount, Z. D., Borland, C. Z., & Lenski, R. E. (2008) · Proceedings of the National Academy of Sciences
Evolution and Genetic DynamicsPhilosophy of Biology and Scientific Explanation
Cited by 840
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Loss of PTEN facilitates HIF-1-mediated gene expression
Zundel, W., Schindler, C., Haas-Kogan, D., Koong, A., Kaper, F., Chen, E., Gottschalk, A. R., Ryan, H. E., Johnson, R. S., Jefferson, A. B., et al. (2000) · Genes & Development
Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 840
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A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
Davie, K., Janssens, J., Koldere, D., De Waegeneer, M., Pech, U., Kreft, Ł., Aibar, S., Makhzami, S., Christiaens, V., Bravo González-Blas, C., et al. (2018) · Cell
Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms
Cited by 840
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Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Shiba, Y., Gomibuchi, T., Seto, T., Wada, Y., Ichimura, H., Tanaka, Y., Ogasawara, T., Okada, K., Shiba, N., Sakamoto, K., et al. (2016) · Nature
Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine
Cited by 840
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Therapeutic siRNA silencing in inflammatory monocytes in mice
Leuschner, F., Dutta, P., Gorbatov, R., Novobrantseva, T. I., Donahoe, J. S., Courties, G., Lee, K. M., Kim, J. I., Markmann, J. F., Marinelli, B., et al. (2011) · Nature Biotechnology
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 839
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Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature
Viswanathan, S., Shi, Y., Galipeau, J., Krampera, M., Leblanc, K., Martin, I., Nolta, J., Phinney, D. G., & Sensebe, L. (2019) · Cytotherapy
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 839
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Microbial strain-level population structure and genetic diversity from metagenomes
Truong, D. T., Tett, A., Pasolli, E., Huttenhower, C., & Segata, N. (2017) · Genome Research
Gut microbiota and healthGenomics and Phylogenetic Studies
Cited by 839
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FORMATION AND FUNCTION OF SPEMANN'S ORGANIZER
Harland, R., & Gerhart, J. (1997) · Annual Review of Cell and Developmental Biology
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 839
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Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients
Rodrigues, T. S., de Sá, K. S. G., Ishimoto, A. Y., Becerra, A., Oliveira, S., Almeida, L., Gonçalves, A. V., Perucello, D. B., Andrade, W. A., Castro, R., et al. (2021) · Journal of Experimental Medicine
Inflammasome and immune disordersCOVID-19 Clinical Research Studies
Cited by 839
- Verified
Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation
Asakura, A., Rudnicki, M. A., & Komaki, M. (2001) · Differentiation
Muscle Physiology and DisordersMesenchymal stem cell research
Cited by 839
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Structure of a c-Cbl–UbcH7 Complex
Zheng, N., Wang, P., Jeffrey, P. D., & Pavletich, N. P. (2000) · Cell
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 839
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Reprogramming human T cell function and specificity with non-viral genome targeting
Roth, T. L., Puig-Saus, C., Yu, R., Shifrut, E., Carnevale, J., Li, P. J., Hiatt, J., Saco, J., Krystofinski, P., Li, H., et al. (2018) · Nature
CRISPR and Genetic EngineeringCAR-T cell therapy research
Cited by 839
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Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
Wang, X.-J., Sun, Z., Villeneuve, N. F., Zhang, S., Zhao, F., Li, Y., Chen, W., Yi, X., Zheng, W., Wondrak, G. T., et al. (2008) · Carcinogenesis
Genomics, phytochemicals, and oxidative stressDrug Transport and Resistance Mechanisms
Cited by 839
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Low-Density Lipoprotein Receptor-Related Protein-5 Binds to Axin and Regulates the Canonical Wnt Signaling Pathway
Mao, J., Wang, J., Liu, B., Pan, W., Farr, G. H., Flynn, C., Yuan, H., Takada, S., Kimelman, D., Li, L., et al. (2001) · Molecular Cell
Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease
Cited by 839
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Peroxisomes and oxidative stress
Schrader, M., & Fahimi, H. D. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 838
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Gene expression across mammalian organ development
Cardoso-Moreira, M., Halbert, J., Valloton, D., Velten, B., Chen, C., Shao, Y., Liechti, A., Ascenção, K., Rummel, C., Ovchinnikova, S., et al. (2019) · Nature
Developmental Biology and Gene RegulationGenomics and Phylogenetic Studies
Cited by 838
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Genomic imprinting: the emergence of an epigenetic paradigm
Ferguson-Smith, A. C. (2011) · Nature Reviews Genetics
Genetic Syndromes and ImprintingEpigenetics and DNA Methylation
Cited by 838
- Verified
Autophagy during viral infection — a double-edged sword
Choi, Y., Bowman, J. W., & Jung, J. U. (2018) · Nature Reviews Microbiology
Autophagy in Disease and Therapyinterferon and immune responses
Cited by 838
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