Most cited biochemistry, genetics and molecular biology papers
- Verified
Multiplexed quantification of proteins and transcripts in single cells
Peterson, V. M., Zhang, K. X., Kumar, N., Wong, J., Li, L., Wilson, D. C., Moore, R., McClanahan, T. K., Sadekova, S., & Klappenbach, J. A. (2017) · Nature Biotechnology
Single-cell and spatial transcriptomicsInnovative Microfluidic and Catalytic Techniques Innovation
Cited by 832
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Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation
Sorger, P. K., & Pelham, H. R. B. (1988) · Cell
Heat shock proteins researchFungal and yeast genetics research
Cited by 832
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Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs
Gascoigne, K. E., & Taylor, S. S. (2008) · Cancer Cell
Microtubule and mitosis dynamicsCell death mechanisms and regulation
Cited by 832
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Understanding multicellular function and disease with human tissue-specific networks
Greene, C. S., Krishnan, A., Wong, A. K., Ricciotti, E., Zelaya, R. A., Himmelstein, D. S., Zhang, R., Hartmann, B. M., Zaslavsky, E., Sealfon, S. C., et al. (2015) · Nature Genetics
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 832
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Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
Quirós, P. M., Prado, M. A., Zamboni, N., D’Amico, D., Williams, R. W., Finley, D., Gygi, S. P., & Auwerx, J. (2017) · Journal of Cell Biology
Endoplasmic Reticulum Stress and DiseaseMitochondrial Function and Pathology
Cited by 832
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Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation
Dominguez, A. A., Lim, W. A., & Qi, L. S. (2016) · Nature Reviews Molecular Cell Biology
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 832
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Normal table of postembryonic zebrafish development: Staging by externally visible anatomy of the living fish
Parichy, D. M., Elizondo, M. R., Mills, M. G., Gordon, T. N., & Engeszer, R. E. (2009) · Developmental Dynamics
Zebrafish Biomedical Research ApplicationsDevelopmental Biology and Gene Regulation
Cited by 832
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Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism
Bach, D., Pich, S., Soriano, F. X., Vega, N., Baumgartner, B., Oriola, J., Daugaard, J. R., Lloberas, J., Camps, M., Zierath, J. R., et al. (2003) · Journal of Biological Chemistry
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 832
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ACMG recommendations for standards for interpretation and reporting of sequence variations: Revisions 2007
Richards, C. S., Bale, S., Bellissimo, D. B., Das, S., Grody, W. W., Hegde, M. R., Lyon, E., & Ward, B. E. (2008) · Genetics in Medicine
Genomics and Rare DiseasesClinical Laboratory Practices and Quality Control
Cited by 832
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Transcriptomic diversity of cell types across the adult human brain
Siletti, K., Hodge, R., Mossi Albiach, A., Lee, K. W., Ding, S.-L., Hu, L., Lönnerberg, P., Bakken, T., Casper, T., Clark, M., et al. (2023) · Science
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 832
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The Gut Microbiota Plays a Protective Role in the Host Defence Against Pneumococcal Pneumonia
Schuijt, T. J., Lankelma, J. M., Scicluna, B. P., de Sousa e Melo, F., Roelofs, J. J. T. H., de Boer, J. D., Hoogendijk, A. J., de Beer, R., de Vos, A., Belzer, C., et al. (2016) · Gut
Gut microbiota and healthPneumonia and Respiratory Infections
Cited by 832
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3D structures of individual mammalian genomes studied by single-cell Hi-C
Stevens, T. J., Lando, D., Basu, S., Atkinson, L. P., Cao, Y., Lee, S. F., Leeb, M., Wohlfahrt, K. J., Boucher, W., O’Shaughnessy-Kirwan, A., et al. (2017) · Nature
Genomics and Chromatin DynamicsNuclear Structure and Function
Cited by 832
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Topological defects in epithelia govern cell death and extrusion
Saw, T. B., Doostmohammadi, A., Nier, V., Kocgozlu, L., Thampi, S., Toyama, Y., Marcq, P., Lim, C. T., Yeomans, J. M., & Ladoux, B. (2017) · Nature
Cellular Mechanics and InteractionsCell death mechanisms and regulation
Cited by 831
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Functional improvement of dystrophic muscle by myostatin blockade
Bogdanovich, S., Krag, T. O. B., Barton, E. R., Morris, L. D., Whittemore, L.-A., Ahima, R. S., & Khurana, T. S. (2002) · Nature
Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research
Cited by 831
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Protein Sequence Analysis Using the MPI Bioinformatics Toolkit
Gabler, F., Nam, S., Till, S., Mirdita, M., Steinegger, M., Söding, J., Lupas, A. N., & Alva, V. (2020) · Current Protocols in Bioinformatics
Genomics and Phylogenetic StudiesProtein Structure and Dynamics
Cited by 831
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Improving genetic diagnosis in Mendelian disease with transcriptome sequencing
Cummings, B. B., Marshall, J. L., Tukiainen, T., Lek, M., Donkervoort, S., Foley, A. R., Bolduc, V., Waddell, L. B., Sandaradura, S. A., O’Grady, G. L., et al. (2017) · Science Translational Medicine
Genomics and Rare DiseasesConnective tissue disorders research
Cited by 831
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Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
Chen, X., He, W.-T., Hu, L., Li, J., Fang, Y., Wang, X., Xu, X., Wang, Z., Huang, K., & Han, J. (2016) · Cell Research
Inflammasome and immune disordersCell death mechanisms and regulation
Cited by 831
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STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer
Iliopoulos, D., Jaeger, S. A., Hirsch, H. A., Bulyk, M. L., & Struhl, K. (2010) · Molecular Cell
MicroRNA in disease regulationCytokine Signaling Pathways and Interactions
Cited by 830
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Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation
Carr, E. L., Kelman, A., Wu, G. S., Gopaul, R., Senkevitch, E., Aghvanyan, A., Turay, A. M., & Frauwirth, K. A. (2010) · The Journal of Immunology
Amino Acid Enzymes and MetabolismT-cell and B-cell Immunology
Cited by 830
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Supercomplex assembly determines electron flux in the mitochondrial electron transport chain
Lapuente-Brun, E., Moreno-Loshuertos, R., Acín-Pérez, R., Latorre-Pellicer, A., Colás, C., Balsa, E., Perales-Clemente, E., Quirós, P. M., Calvo, E., Rodríguez-Hernández, M. A., et al. (2013) · Science
Mitochondrial Function and PathologyCoenzyme Q10 studies and effects
Cited by 830
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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
Fisher, F. M., Chui, P. C., Antonellis, P. J., Bina, H. A., Kharitonenkov, A., Flier, J. S., & Maratos-Flier, E. (2010) · Diabetes
Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases
Cited by 830
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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
Laybutt, D. R., Preston, A. M., Åkerfeldt, M. C., Kench, J. G., Busch, A. K., Biankin, A. V., & Biden, T. J. (2007) · Diabetologia
Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes
Cited by 830
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The mTOR Signalling Pathway in Human Cancer
Pópulo, H., Lopes, J. M., & Soares, P. (2012) · International Journal of Molecular Sciences
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 830
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Gut Microbiota Orchestrates Energy Homeostasis during Cold
Chevalier, C., Stojanović, O., Colin, D. J., Suarez-Zamorano, N., Tarallo, V., Veyrat-Durebex, C., Rigo, D., Fabbiano, S., Stevanović, A., Hagemann, S., et al. (2015) · Cell
Gut microbiota and healthAdipose Tissue and Metabolism
Cited by 829
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