Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Autophagy and aging: The importance of maintaining "clean" cells

Cuervo, A. M., Bergamini, E., Brunk, U. T., Dröge, W., Ffrench, M., & Terman, A. (2005) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 792

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

Liang, C., Lee, J.-S., Inn, K.-S., Gack, M. U., Li, Q., Roberts, E. A., Vergne, I., Deretic, V., Feng, P., Akazawa, C., et al. (2008) · Nature Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 792

Integrating high-throughput and computational data elucidates bacterial networks

Covert, M. W., Knight, E. M., Reed, J. L., Herrgard, M. J., & Palsson, B. O. (2004) · Nature

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 792

Scaling single-cell genomics from phenomenology to mechanism

Tanay, A., & Regev, A. (2017) · Nature

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 792

Rate, molecular spectrum, and consequences of human mutation

Lynch, M. (2010) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsGenomics and Rare Diseases

Cited by 792

Intrinsic Disorder in Transcription Factors

Liu, J., Perumal, N. B., Oldfield, C. J., Su, E. W., Uversky, V. N., & Dunker, A. K. (2006) · Biochemistry

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 792

Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data

Pratapa, A., Jalihal, A. P., Law, J. N., Bharadwaj, A., & Murali, T. M. (2020) · Nature Methods

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 792

Bayesian Selection of Continuous-Time Markov Chain Evolutionary Models

Suchard, M. A., Weiss, R. E., & Sinsheimer, J. S. (2001) · Molecular Biology and Evolution

Genomics and Phylogenetic StudiesMarkov Chains and Monte Carlo Methods

Cited by 791

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

Shumaker, D. K., Dechat, T., Kohlmaier, A., Adam, S. A., Bozovsky, M. R., Erdos, M. R., Eriksson, M., Goldman, A. E., Khuon, S., Collins, F. S., et al. (2006) · Proceedings of the National Academy of Sciences

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 791

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

Yan, A. W., Fouts, D. E., Brandl, J., Stärkel, P., Torralba, M., Schott, E., Tsukamoto, H., Nelson, K. E., Brenner, D. A., & Schnabl, B. (2011) · Hepatology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 791

Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

Vich Vila, A., Collij, V., Sanna, S., Sinha, T., Imhann, F., Bourgonje, A. R., Mujagic, Z., Jonkers, D. M. A. E., Masclee, A. A. M., Fu, J., et al. (2020) · Nature Communications

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 791

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

Yeh, E., Cunningham, M., Arnold, H., Chasse, D., Monteith, T., Ivaldi, G., Hahn, W. C., Stukenberg, P. T., Shenolikar, S., Uchida, T., et al. (2004) · Nature Cell Biology

Signaling Pathways in DiseaseProtein Kinase Regulation and GTPase Signaling

Cited by 791

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

Mizushima, N., Kuma, A., Kobayashi, Y., Yamamoto, A., Matsubae, M., Takao, T., Natsume, T., Ohsumi, Y., & Yoshimori, T. (2003) · Journal of Cell Science

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 791

The microbiome in infectious disease and inflammation

Honda, K., & Littman, D. R. (2012) · Annual Review of Immunology

Gut microbiota and healthImmune Response and Inflammation

Cited by 791

Disease variant prediction with deep generative models of evolutionary data

Frazer, J., Notin, P., Dias, M., Gomez, A., Min, J. K., Brock, K., Gal, Y., & Marks, D. S. (2021) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 791

Large-scale whole-genome sequencing of the Icelandic population

Gudbjartsson, D. F., Helgason, H., Gudjonsson, S. A., Zink, F., Oddson, A., Gylfason, A., Besenbacher, S., Magnusson, G., Halldorsson, B. V., Hjartarson, E., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 791

Cellular and Molecular Mechanisms of Metformin Action

LaMoia, T. E., & Shulman, G. I. (2021) · Endocrine Reviews

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 791

Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans

Civitarese, A. E., Carling, S., Heilbronn, L. K., Hulver, M. H., Ukropcova, B., Deutsch, W. A., Smith, S. R., & Ravussin, E. (2007) · PLoS Medicine

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 790

A skin microRNA promotes differentiation by repressing ‘stemness’

Yi, R., Poy, M. N., Stoffel, M., & Fuchs, E. (2008) · Nature

MicroRNA in disease regulationHair Growth and Disorders

Cited by 790

HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk

Erlich, H., Valdes, A. M., Noble, J., Carlson, J. A., Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., et al. (2008) · Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 790

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

Sedelnikova, O. A., Horikawa, I., Zimonjic, D. B., Popescu, N. C., Bonner, W. M., & Barrett, J. C. (2004) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 790

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

Baroja-Mazo, A., Martín-Sánchez, F., Gomez, A. I., Martínez, C. M., Amores-Iniesta, J., Compan, V., Barberà-Cremades, M., Yagüe, J., Ruiz-Ortiz, E., Antón, J., et al. (2014) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 790

Cancer cell killing via ROS: To increase or decrease, that is the question

Wang, J., & Yi, J. (2008) · Cancer Biology & Therapy

Redox biology and oxidative stressCancer and biochemical research

Cited by 790

IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer

Gyrd-Hansen, M., & Meier, P. (2010) · Nature Reviews Cancer

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 790