Most cited biochemistry, genetics and molecular biology papers
- Verified
The glucocorticoid receptor: rapid exchange with regulatory sites in living cells
McNally, J. G., Müller, W. G., Walker, D., Wolford, R., & Hager, G. L. (2000) · Science
Estrogen and related hormone effectsGenomics and Chromatin Dynamics
Cited by 802
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UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis
Koizumi, S., Shigemoto-Mogami, Y., Nasu-Tada, K., Shinozaki, Y., Ohsawa, K., Tsuda, M., Joshi, B. V., Jacobson, K. A., Kohsaka, S., & Inoue, K. (2007) · Nature
Adenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms
Cited by 802
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Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
Wong, G. H. W., Elwell, J. H., Oberley, L. W., & Goeddel, D. V. (1989) · Cell
Cell death mechanisms and regulationRedox biology and oxidative stress
Cited by 802
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Distinct DNA methylomes of newborns and centenarians
Heyn, H., Li, N., Ferreira, H. J., Moran, S., Pisano, D. G., Gomez, A., Diez, J., Sanchez-Mut, J. V., Setien, F., Carmona, F. J., et al. (2012) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 802
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The complex transcriptional landscape of the anucleate human platelet
Bray, P. F., McKenzie, S. E., Edelstein, L. C., Nagalla, S., Delgrosso, K., Ertel, A., Kupper, J., Jing, Y., Londin, E., Loher, P., et al. (2013) · BMC Genomics
Genomics and Phylogenetic StudiesPlatelet Disorders and Treatments
Cited by 802
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Metabolic network structure determines key aspects of functionality and regulation
Stelling, J., Klamt, S., Bettenbrock, K., Schuster, S., & Gilles, E. D. (2002) · Nature
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 802
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Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling
Boutros, M., Paricio, N., Strutt, D. I., & Mlodzik, M. (1998) · Cell
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 801
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CHO cells in biotechnology for production of recombinant proteins: current state and further potential
Kim, J. Y., Kim, Y.-G., & Lee, G. M. (2012) · Applied Microbiology and Biotechnology
Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability
Cited by 801
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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
Mansour, M. R., Abraham, B. J., Anders, L., Berezovskaya, A., Gutierrez, A., Durbin, A. D., Etchin, J., Lawton, L., Sallan, S. E., Silverman, L. B., et al. (2014) · Science
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 801
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Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Quach, A., Levine, M. E., Tanaka, T., Lu, A. T., Chen, B. H., Ferrucci, L., Ritz, B., Bandinelli, S., Neuhouser, M. L., Beasley, J. M., et al. (2017) · Aging
Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms
Cited by 801
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Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
Neumann, C. A., Krause, D. S., Carman, C. V., Das, S., Dubey, D. P., Abraham, J. L., Bronson, R. T., Fujiwara, Y., Orkin, S. H., & Van Etten, R. A. (2003) · Nature
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 801
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Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors
Lekstrom-Himes, J., & Xanthopoulos, K. G. (1998) · Journal of Biological Chemistry
Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions
Cited by 801
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An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
Greer, E. L., Dowlatshahi, D., Banko, M. R., Villen, J., Hoang, K., Blanchard, D., Gygi, S. P., & Brunet, A. (2007) · Current Biology
Genetics, Aging, and Longevity in Model OrganismsFOXO transcription factor regulation
Cited by 801
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Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A
Butler, K. V., Kalin, J., Brochier, C., Vistoli, G., Langley, B., & Kozikowski, A. P. (2010) · Journal of the American Chemical Society
Histone Deacetylase Inhibitors ResearchCholinesterase and Neurodegenerative Diseases
Cited by 801
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Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases
Kanai, M., Akiyama, M., Takahashi, A., Matoba, N., Momozawa, Y., Ikeda, M., Iwata, N., Ikegawa, S., Hirata, M., Matsuda, K., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 801
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TGF-β1 Signaling and Tissue Fibrosis
Kim, K. K., Sheppard, D., & Chapman, H. A. (2018) · Cold Spring Harbor Perspectives in Biology
TGF-β signaling in diseasesLiver physiology and pathology
Cited by 800
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Human Embryonic Stem Cells Develop Into Multiple Types of Cardiac Myocytes: Action Potential Characterization
He, J.-Q., Ma, Y., Lee, Y., Thomson, J. A., & Kamp, T. J. (2003) · Circulation Research
Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias
Cited by 800
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Characterization of Dicer-deficient murine embryonic stem cells
Murchison, E. P., Partridge, J. F., Tam, O. H., Cheloufi, S., & Hannon, G. J. (2005) · Proceedings of the National Academy of Sciences
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 800
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Improving the coverage of the cyanobacterial phylum using diversity driven genome sequencing
Shih, P. M., Wu, D., Latifi, A., Axen, S. D., Fewer, D. P., Talla, E., Calteau, A., Cai, F., Tandeau de Marsac, N., Rippka, R., et al. (2013) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesPhotosynthetic Processes and Mechanisms
Cited by 800
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Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants
Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., & Zon, L. I. (2003) · Nature Immunology
Zebrafish Biomedical Research ApplicationsHematopoietic Stem Cell Transplantation
Cited by 800
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Ubiquitination and selective autophagy
Shaid, S., Brandts, C. H., Serve, H., & Dikic, I. (2013) · Cell Death & Differentiation
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 800
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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Williams, A., Sarkar, S., Cuddon, P., Ttofi, E. K., Saiki, S., Siddiqi, F. H., Jahreiss, L., Fleming, A., Pask, D., Goldsmith, P., et al. (2008) · Nature Chemical Biology
Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases
Cited by 800
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A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
Garg, A. D., Krysko, D. V., Verfaillie, T., Kaczmarek, A., Ferreira, G. B., Marysael, T., Rubio, N., Firczuk, M., Mathieu, C., Roebroek, A. J. M., et al. (2012) · The EMBO Journal
Endoplasmic Reticulum Stress and DiseaseCell death mechanisms and regulation
Cited by 800
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Connecting genetic risk to disease end points through the human blood plasma proteome
Suhre, K., Arnold, M., Bhagwat, A. M., Cotton, R. J., Engelke, R., Raffler, J., Sarwath, H., Thareja, G., Wahl, A., DeLisle, R. K., et al. (2017) · Nature Communications
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 800
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