Most cited biochemistry, genetics and molecular biology papers
- Verified
Non-viral vectors for gene-based therapy
Yin, H., Kanasty, R. L., Eltoukhy, A. A., Vegas, A. J., Dorkin, J. R., & Anderson, D. G. (2014) · Nature Reviews Genetics
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 3,123
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VEGF receptor signalling ? in control of vascular function
Olsson, A.-K., Dimberg, A., Kreuger, J., & Claesson-Welsh, L. (2006) · Nature Reviews Molecular Cell Biology
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 3,122
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Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
Srinivas, S., Watanabe, T., Lin, C.-S., William, C. M., Tanabe, Y., Jessell, T. M., & Costantini, F. (2001) · BMC Developmental Biology
Developmental Biology and Gene RegulationAnimal Genetics and Reproduction
Cited by 3,121
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Short chain fatty acids in human large intestine, portal, hepatic and venous blood
Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P., & Macfarlane, G. T. (1987) · Gut
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 3,119
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Knocking down barriers: advances in siRNA delivery
Whitehead, K. A., Langer, R., & Anderson, D. G. (2009) · Nature Reviews Drug Discovery
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 3,115
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Gut metagenome in European women with normal, impaired and diabetic glucose control
Karlsson, F. H., Tremaroli, V., Nookaew, I., Bergström, G., Behre, C. J., Fagerberg, B., Nielsen, J., & Bäckhed, F. (2013) · Nature
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 3,115
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Histone deacetylases (HDACs): characterization of the classical HDAC family
RUIJTER, A. J. M. D., GENNIP, A. H. V., CARON, H. N., KEMP, S., & KUILENBURG, A. B. P. V. (2003) · Biochemical Journal
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 3,114
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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
Maehama, T., & Dixon, J. E. (1998) · Journal of Biological Chemistry
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 3,104
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Mitochondrial control of cell death
Kroemer, G., & Reed, J. C. (2000) · Nature Medicine
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 3,103
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Mitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 3,100
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Simultaneous epitope and transcriptome measurement in single cells
Stoeckius, M., Hafemeister, C., Stephenson, W., Houck-Loomis, B., Chattopadhyay, P. K., Swerdlow, H., Satija, R., & Smibert, P. (2017) · Nature Methods
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 3,098
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Towards complete and error-free genome assemblies of all vertebrate species
Rhie, A., McCarthy, S. A., Fedrigo, O., Damas, J., Formenti, G., Koren, S., Uliano-Silva, M., Chow, W., Fungtammasan, A., Kim, J., et al. (2021) · Nature
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 3,097
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Discovery and saturation analysis of cancer genes across 21 tumour types
Lawrence, M. S., Stojanov, P., Mermel, C. H., Robinson, J. T., Garraway, L. A., Golub, T. R., Meyerson, M., Gabriel, S. B., Lander, E. S., & Getz, G. (2014) · Nature
Cancer Genomics and DiagnosticsGenomics and Rare Diseases
Cited by 3,096
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DNA methylation-based biomarkers and the epigenetic clock theory of ageing
Horvath, S., & Raj, K. (2018) · Nature Reviews Genetics
Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms
Cited by 3,095
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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007) · Genes & Development
Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research
Cited by 3,092
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A protein factor essential for microtubule assembly
Weingarten, M. D., Lockwood, A. H., Hwo, S. Y., & Kirschner, M. W. (1975) · Proceedings of the National Academy of Sciences
Microtubule and mitosis dynamicsAlzheimer's disease research and treatments
Cited by 3,089
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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
Shi, J., Gao, W., & Shao, F. (2017) · Trends in Biochemical Sciences
Inflammasome and immune disordersCell death mechanisms and regulation
Cited by 3,088
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Ferroptosis: Death by Lipid Peroxidation
Yang, W. S., & Stockwell, B. R. (2016) · Trends in Cell Biology
Ferroptosis and cancer prognosisCell death mechanisms and regulation
Cited by 3,088
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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Inoki, K., Li, Y., Zhu, T., Wu, J., & Guan, K.-L. (2002) · Nature Cell Biology
PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research
Cited by 3,083
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An anatomically comprehensive atlas of the adult human brain transcriptome
Hawrylycz, M. J., Lein, E. S., Guillozet-Bongaarts, A. L., Shen, E. H., Ng, L., Miller, J. A., van de Lagemaat, L. N., Smith, K. A., Ebbert, A., Riley, Z. L., et al. (2012) · Nature
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 3,083
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circRNA biogenesis competes with pre-mRNA splicing
Ashwal-Fluss, R., Meyer, M., Pamudurti, N. R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N., & Kadener, S. (2014) · Molecular Cell
Circular RNAs in diseasesRNA Research and Splicing
Cited by 3,083
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 3,082
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Cryopyrin activates the inflammasome in response to toxins and ATP
Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 3,080
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Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
Bianchini, G., Balko, J. M., Mayer, I. A., Sanders, M. E., & Gianni, L. (2016) · Nature Reviews Clinical Oncology
Breast Cancer Treatment StudiesBRCA gene mutations in cancer
Cited by 3,079
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