Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Inflammasomes: mechanism of action, role in disease, and therapeutics

Guo, H., Callaway, J. B., & Ting, J. P.-Y. (2015) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,340

Dynamic instability of microtubule growth

Mitchison, T., & Kirschner, M. (1984) · Nature

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

Cited by 3,337

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Epstein, A. C. R., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., et al. (2001) · Cell

Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 3,333

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Nielsen, P. E., Egholm, M., Berg, R. H., & Buchardt, O. (1991) · Science

DNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques

Cited by 3,332

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

Engelman, J. A., Luo, J., & Cantley, L. C. (2006) · Nature Reviews Genetics

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 3,330

The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution

Ban, N., Nissen, P., Hansen, J., Moore, P. B., & Steitz, T. A. (2000) · Science

RNA and protein synthesis mechanismsEnzyme Structure and Function

Cited by 3,327

Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial

de Bono, J. S., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J.-P., Kocak, I., Gravis, G., Bodrogi, I., Mackenzie, M. J., Shen, L., et al. (2010) · The Lancet

Prostate Cancer Treatment and ResearchCancer Treatment and Pharmacology

Cited by 3,318

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 3,317

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., et al. (2015) · Cell Host & Microbe

Gut microbiota and healthInfant Nutrition and Health

Cited by 3,315

Gut microbiota composition correlates with diet and health in the elderly

Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature

Gut microbiota and healthNutritional Studies and Diet

Cited by 3,314

Ageing as a risk factor for neurodegenerative disease

Hou, Y., Dan, X., Babbar, M., Wei, Y., Hasselbalch, S. G., Croteau, D. L., & Bohr, V. A. (2019) · Nature Reviews Neurology

Genetics, Aging, and Longevity in Model OrganismsAlzheimer's disease research and treatments

Cited by 3,310

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Harding, H. P., Zhang, Y., & Ron, D. (1999) · Nature

Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms

Cited by 3,310

Prediction of protein conformation

Chou, P. Y., & Fasman, G. D. (1974) · Biochemistry

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 3,309

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

Sonenberg, N., & Hinnebusch, A. G. (2009) · Cell

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 3,304

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P., & Auwerx, J. (2009) · Nature

Metabolism, Diabetes, and CancerSirtuins and Resveratrol in Medicine

Cited by 3,300

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

Ran, F. A., Hsu, P. D., Lin, C.-Y., Gootenberg, J. S., Konermann, S., Trevino, A. E., Scott, D. A., Inoue, A., Matoba, S., Zhang, Y., et al. (2013) · Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 3,299

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry.

The Human Serum Metabolome (HUSERMET) Consortium, Dunn, W. B., Broadhurst, D., Begley, P., Zelena, E., Francis-McIntyre, S., Anderson, N., Brown, M., Knowles, J. D., Halsall, A., et al. (2011) · Nature Protocols

Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and Applications

Cited by 3,294

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., Mitchell, P. S., Bennett, C. F., Pogosova-Agadjanyan, E. L., Stirewalt, D. L., et al. (2011) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 3,294

High-Frequency off-Target Mutagenesis Induced by CRISPR-Cas Nucleases in Human Cells

Fu, Y., Foden, J. A., Khayter, C., Maeder, M. L., Reyon, D., Joung, J. K., & Sander, J. D. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 3,292

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

Tsai, M.-C., Manor, O., Wan, Y., Mosammaparast, N., Wang, J. K., Lan, F., Shi, Y., Segal, E., & Chang, H. Y. (2010) · Science

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 3,290

Autophagy in immunity and inflammation

Levine, B., Mizushima, N., & Virgin, H. W. (2011) · Nature

Autophagy in Disease and TherapyImmune Response and Inflammation

Cited by 3,289

Cell Movement Is Guided by the Rigidity of the Substrate

Lo, C.-M., Wang, H.-B., Dembo, M., & Wang, Y.-L. (2000) · Biophysical Journal

Cellular Mechanics and InteractionsForce Microscopy Techniques and Applications

Cited by 3,289

ATAC-seq: a method for assaying chromatin accessibility genome-wide

Buenrostro, J. D., Wu, B., Chang, H. Y., & Greenleaf, W. J. (2015) · Current Protocols in Molecular Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 3,289

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Kaplan, R. N., Riba, R. D., Zacharoulis, S., Bramley, A. H., Vincent, L., Costa, C., MacDonald, D. D., Jin, D. K., Shido, K., Kerns, S. A., et al. (2005) · Nature

Angiogenesis and VEGF in CancerCancer Cells and Metastasis

Cited by 3,288