Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The GTPase superfamily: conserved structure and molecular mechanism

Bourne, H. R., Sanders, D. A., & McCormick, F. (1991) · Nature

Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling

Cited by 3,392

A C. elegans mutant that lives twice as long as wild type

Kenyon, C., Chang, J., Gensch, E., Rudner, A., & Tabtiang, R. (1993) · Nature

Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research

Cited by 3,387

Rab proteins as membrane organizers

Zerial, M., & McBride, H. (2001) · Nature Reviews Molecular Cell Biology

Cellular transport and secretionExtracellular vesicles in disease

Cited by 3,381

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Zehir, A., Benayed, R., Shah, R. H., Syed, A., Middha, S., Kim, H. R., Srinivasan, P., Gao, J., Chakravarty, D., Devlin, S. M., et al. (2017) · Nature Medicine

Cancer Genomics and DiagnosticsBRCA gene mutations in cancer

Cited by 3,380

SeqKit: A Cross-Platform and Ultrafast Toolkit for FASTA/Q File Manipulation

Shen, W., Le, S., Li, Y., & Hu, F. (2016) · PLOS ONE

Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research

Cited by 3,380

Improved protein structure prediction using potentials from deep learning

Senior, A. W., Evans, R., Jumper, J., Kirkpatrick, J., Sifre, L., Green, T., Qin, C., Žídek, A., Nelson, A. W. R., Bridgland, A., et al. (2020) · Nature

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 3,378

Mash: fast genome and metagenome distance estimation using MinHash

Ondov, B. D., Treangen, T. J., Melsted, P., Mallonee, A. B., Bergman, N. H., Koren, S., & Phillippy, A. M. (2016) · Genome biology

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 3,373

A pathology atlas of the human cancer transcriptome

Uhlen, M., Zhang, C., Lee, S., Sjöstedt, E., Fagerberg, L., Bidkhori, G., Benfeitas, R., Arif, M., Liu, Z., Edfors, F., et al. (2017) · Science

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 3,371

Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue

Kern, S., Eichler, H., Stoeve, J., Klüter, H., & Bieback, K. (2006) · STEM CELLS

Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation

Cited by 3,370

TFEB Links Autophagy to Lysosomal Biogenesis

Settembre, C., Di Malta, C., Polito, V. A., Arencibia, M. G., Vetrini, F., Erdin, S., Erdin, S. U., Huynh, T., Medina, D., Colella, P., et al. (2011) · Science

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,365

Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine

Ley, R. E., Peterson, D. A., & Gordon, J. I. (2006) · Cell

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 3,358

The role of short-chain fatty acids in microbiota–gut–brain communication

Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K. (2019) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 3,357

Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells

Klein, A. M., Mazutis, L., Akartuna, I., Tallapragada, N., Veres, A., Li, V., Peshkin, L., Weitz, D. A., & Kirschner, M. W. (2015) · Cell

Single-cell and spatial transcriptomicsInnovative Microfluidic and Catalytic Techniques Innovation

Cited by 3,356

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

Eden, E., Navon, R., Steinfeld, I., Lipson, D., & Yakhini, Z. (2009) · BMC Bioinformatics

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 3,356

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,355

Molecular basis of agonism and antagonism in the oestrogen receptor

Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engström, O., Öhman, L., Greene, G. L., Gustafsson, J.-Å., & Carlquist, M. (1997) · Nature

Estrogen and related hormone effectsReceptor Mechanisms and Signaling

Cited by 3,355

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M. R., Powell, J. E., Montgomery, G. W., Goddard, M. E., Wray, N. R., Visscher, P. M., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 3,352

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

Kong, Y.-Y., Yoshida, H., Sarosi, I., Tan, H.-L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A., et al. (1999) · Nature

Bone Metabolism and DiseasesT-cell and B-cell Immunology

Cited by 3,351

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., & Levine, B. (1999) · Nature

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 3,347

The Polycomb complex PRC2 and its mark in life

Margueron, R., & Reinberg, D. (2011) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 3,347

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

Lau, N. C., Lim, L. P., Weinstein, E. G., & Bartel, D. P. (2001) · Science

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 3,345

A Third-Generation Lentivirus Vector with a Conditional Packaging System

Dull, T., Zufferey, R., Kelly, M., Mandel, R. J., Nguyen, M., Trono, D., & Naldini, L. (1998) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 3,341

FSP1 is a glutathione-independent ferroptosis suppressor

Doll, S., Freitas, F. P., Shah, R., Aldrovandi, M., da Silva, M. C., Ingold, I., Goya Grocin, A., Xavier da Silva, T. N., Panzilius, E., Scheel, C. H., et al. (2019) · Nature

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 3,341

Reactive oxygen species, cellular redox systems, and apoptosis

Circu, M. L., & Aw, T. Y. (2010) · Free Radical Biology and Medicine

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 3,340