Most cited biochemistry, genetics and molecular biology papers
- Verified
Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
Rives, A., Meier, J., Sercu, T., Goyal, S., Lin, Z., Liu, J., Guo, D., Ott, M., Zitnick, C. L., Ma, J., et al. (2021) · Proceedings of the National Academy of Sciences
Machine Learning in BioinformaticsProtein Structure and Dynamics
Cited by 3,286
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Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., Codelli, J. A., Chow, J., Reisman, S. E., Petrosino, J. F., et al. (2013) · Cell
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 3,283
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Network motifs: theory and experimental approaches
Alon, U. (2007) · Nature Reviews Genetics
Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics
Cited by 3,279
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miRDB: an online database for prediction of functional microRNA targets
Chen, Y., & Wang, X. (2020) · Nucleic Acids Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 3,277
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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology
Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases
Cited by 3,276
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Defining a Cancer Dependency Map
Tsherniak, A., Vazquez, F., Montgomery, P. G., Weir, B. A., Kryukov, G., Cowley, G. S., Gill, S., Harrington, W. F., Pantel, S., Krill-Burger, J. M., et al. (2017) · Cell
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 3,276
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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
Cargnello, M., & Roux, P. P. (2011) · Microbiology and Molecular Biology Reviews
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 3,274
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Mechanisms of mitophagy
Youle, R. J., & Narendra, D. P. (2011) · Nature Reviews Molecular Cell Biology
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 3,273
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Pembrolizumab for Early Triple-Negative Breast Cancer
Schmid, P., Cortes, J., Pusztai, L., McArthur, H., Kümmel, S., Bergh, J., Denkert, C., Park, Y. H., Hui, R., Harbeck, N., et al. (2020) · New England Journal of Medicine
Breast Cancer Treatment StudiesCancer Immunotherapy and Biomarkers
Cited by 3,270
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GenBank
Benson, D. A., Cavanaugh, M., Clark, K., Karsch-Mizrachi, I., Lipman, D. J., Ostell, J., & Sayers, E. W. (2012) · Nucleic Acids Research
Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research
Cited by 3,261
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MicroRNAs Modulate Hematopoietic Lineage Differentiation
Chen, C.-Z., Li, L., Lodish, H. F., & Bartel, D. P. (2004) · Science
MicroRNA in disease regulationHematopoietic Stem Cell Transplantation
Cited by 3,257
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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
Kaelin, W. G., & Ratcliffe, P. J. (2008) · Molecular Cell
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 3,251
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The Energy Landscapes and Motions of Proteins
Frauenfelder, H., Sligar, S. G., & Wolynes, P. G. (1991) · Science
Protein Structure and DynamicsHemoglobin structure and function
Cited by 3,250
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Oxidative DNA damage: mechanisms, mutation, and disease
Cooke, M. S., Evans, M. D., Dizdaroglu, M., & Lunec, J. (2003) · The FASEB Journal
DNA Repair MechanismsCarcinogens and Genotoxicity Assessment
Cited by 3,245
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The human disease network
Goh, K.-I., Cusick, M. E., Valle, D., Childs, B., Vidal, M., & Barabási, A.-L. (2007) · Proceedings of the National Academy of Sciences
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 3,242
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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C., Rolph, M. S., Mackay, F., Artis, D., et al. (2009) · Nature
Gut microbiota and healthInflammatory Bowel Disease
Cited by 3,241
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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science
FOXO transcription factor regulationSirtuins and Resveratrol in Medicine
Cited by 3,239
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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
Frommer, M., McDonald, L. E., Millar, D. S., Collis, C. M., Watt, F., Grigg, G. W., Molloy, P. L., & Paul, C. L. (1992) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 3,238
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Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Ward, P. S., & Thompson, C. B. (2012) · Cancer Cell
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 3,233
- Verified
Epigenetics in human disease and prospects for epigenetic therapy
Egger, G., Liang, G., Aparicio, A., & Jones, P. A. (2004) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 3,232
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Bacterial Community Variation in Human Body Habitats Across Space and Time
Costello, E. K., Lauber, C. L., Hamady, M., Fierer, N., Gordon, J. I., & Knight, R. (2009) · Science
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 3,231
- Verified
Normal gut microbiota modulates brain development and behavior
Heijtz, R. D., Wang, S., Anuar, F., Qian, Y., Björkholm, B., Samuelsson, A., Hibberd, M. L., Forssberg, H., & Pettersson, S. (2011) · Proceedings of the National Academy of Sciences
Gut microbiota and healthNeuroscience and Neuropharmacology Research
Cited by 3,228
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Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
Di Nicola, M., Carlo-Stella, C., Magni, M., Milanesi, M., Longoni, P. D., Matteucci, P., Grisanti, S., & Gianni, A. M. (2002) · Blood
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 3,226
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Cellular Senescence: Defining a Path Forward
Gorgoulis, V., Adams, P. D., Alimonti, A., Bennett, D. C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., et al. (2019) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 3,225
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