Most cited biochemistry, genetics and molecular biology papers
- Verified
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
Chen, H. I., & Sudol, M. (1995) · Proceedings of the National Academy of Sciences
Hippo pathway signaling and YAP/TAZProtein Structure and Dynamics
Cited by 557
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Targeting cells with single vectors using multiple-feature Boolean logic
Fenno, L. E., Mattis, J., Ramakrishnan, C., Hyun, M., Lee, S. Y., He, M., Tucciarone, J., Selimbeyoglu, A., Berndt, A., Grosenick, L., et al. (2014) · Nature Methods
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 557
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Cell-of-origin chromatin organization shapes the mutational landscape of cancer
Polak, P., Karlić, R., Koren, A., Thurman, R., Sandstrom, R., Lawrence, M. S., Reynolds, A., Rynes, E., Vlahoviček, K., Stamatoyannopoulos, J. A., et al. (2015) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 557
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Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity
Long, X., Wong, C. C., Tong, L., Chu, E. S. H., Ho Szeto, C., Go, M. Y. Y., Coker, O. O., Chan, A. W. H., Chan, F. K. L., Sung, J. J. Y., et al. (2019) · Nature Microbiology
Gut microbiota and healthBacterial Cancer Therapy
Cited by 557
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Dysregulation of mTOR signaling in fragile X syndrome
Sharma, A., Hoeffer, C. A., Takayasu, Y., Miyawaki, T., McBride, S. M., Klann, E., & Zukin, R. S. (2010) · The Journal of Neuroscience
Genetics and Neurodevelopmental DisordersPI3K/AKT/mTOR signaling in cancer
Cited by 557
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The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
Samir, P., Malireddi, R. K. S., & Kanneganti, T.-D. (2020) · Frontiers in Cellular and Infection Microbiology
Cell death mechanisms and regulationInflammasome and immune disorders
Cited by 557
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Chromatin accessibility profiling by ATAC-seq
Grandi, F. C., Modi, H., Kampman, L., & Corces, M. R. (2022) · Nature Protocols
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 557
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p16 INK4A is a robust in vivo biomarker of cellular aging in human skin
Ressler, S., Bartkova, J., Niederegger, H., Bartek, J., Scharffetter‐Kochanek, K., Jansen‐Dürr, P., & Wlaschek, M. (2006) · Aging Cell
Telomeres, Telomerase, and SenescenceSkin Protection and Aging
Cited by 557
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Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor
Laudet, V (1997) · Journal of Molecular Endocrinology
Nuclear Receptors and SignalingEstrogen and related hormone effects
Cited by 557
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Dynamics of Replication-Independent Histone Turnover in Budding Yeast
Dion, M. F., Kaplan, T., Kim, M., Buratowski, S., Friedman, N., & Rando, O. J. (2007) · Science
Genomics and Chromatin DynamicsNuclear Structure and Function
Cited by 556
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Mucin-bacterial interactions in the human oral cavity and digestive tract
Derrien, M., van Passel, M. W. J., van de Bovenkamp, J. H. B., Schipper, R., de Vos, W., & Dekker, J. (2010) · Gut Microbes
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 556
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CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
Yun, M. H., & Hiom, K. (2009) · Nature
DNA Repair MechanismsPARP inhibition in cancer therapy
Cited by 556
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Real-Time PCR Quantitation of Clostridia in Feces of Autistic Children
Song, Y., Liu, C., & Finegold, S. M. (2004) · Applied and Environmental Microbiology
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 556
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Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways
Vercammen, D., Brouckaert, G., Denecker, G., Van de Craen, M., Declercq, W., Fiers, W., & Vandenabeele, P. (1998) · The Journal of Experimental Medicine
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 556
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Roles and regulation of histone methylation in animal development
Jambhekar, A., Dhall, A., & Shi, Y. (2019) · Nature Reviews Molecular Cell Biology
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 556
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Molecular aspects of lipoic acid in the prevention of diabetes complications
Packer, L., Kraemer, K., & Rimbach, G. (2001) · Nutrition
Biochemical Acid Research StudiesAldose Reductase and Taurine
Cited by 556
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Function and Structure of Complex II of the Respiratory Chain
Cecchini, G. (2003) · Annual Review of Biochemistry
Enzyme Structure and FunctionMitochondrial Function and Pathology
Cited by 556
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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition
Pereira, B. I., Devine, O. P., Vukmanovic-Stejic, M., Chambers, E. S., Subramanian, P., Patel, N., Virasami, A., Sebire, N. J., Kinsler, V., Valdovinos, A., et al. (2019) · Nature Communications
Telomeres, Telomerase, and SenescenceImmune Cell Function and Interaction
Cited by 556
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Activation of antibacterial autophagy by NADPH oxidases
Huang, J., Canadien, V., Lam, G. Y., Steinberg, B. E., Dinauer, M. C., Magalhaes, M. A. O., Glogauer, M., Grinstein, S., & Brumell, J. H. (2009) · Proceedings of the National Academy of Sciences
Autophagy in Disease and TherapyNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 556
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Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
Gavish, A., Tyler, M., Greenwald, A. C., Hoefflin, R., Simkin, D., Tschernichovsky, R., Galili Darnell, N., Somech, E., Barbolin, C., Antman, T., et al. (2023) · Nature
Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics
Cited by 556
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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.
Chen, J., Zheng, X. F., Brown, E. J., & Schreiber, S. L. (1995) · Proceedings of the National Academy of Sciences
PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease
Cited by 556
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Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
von Karstedt, S., Montinaro, A., & Walczak, H. (2017) · Nature Reviews Cancer
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 556
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The Nature of Nurture: Genetic Influence on “Environmental” Measures
Plomin, R., & Bergeman, C. S. (1991) · Behavioral and Brain Sciences
Genetic Associations and EpidemiologyCognitive Abilities and Testing
Cited by 556
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Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling
Meers, M. P., Tenenbaum, D., & Henikoff, S. (2019) · Epigenetics & Chromatin
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 556
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