Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones?

Churcher, I. (2018) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 491

C-Peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function

Palmer, J. P., Fleming, G. A., Greenbaum, C. J., Herold, K. C., Jansa, L. D., Kolb, H., Lachin, J. M., Polonsky, K. S., Pozzilli, P., Skyler, J. S., et al. (2004) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 491

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

Jiang, P., Du, W., Mancuso, A., Wellen, K. E., & Yang, X. (2013) · Nature

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 491

Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate

Palm, G. J., Reisky, L., Böttcher, D., Müller, H., Michels, E. A. P., Walczak, M. C., Berndt, L., Weiss, M. S., Bornscheuer, U. T., & Weber, G. (2019) · Nature Communications

Enzyme Structure and FunctionEnzyme Production and Characterization

Cited by 491

Peroxisome proliferator-activated receptors: insight into multiple cellular functions

Escher, P., & Wahli, W. (2000) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Peroxisome Proliferator-Activated ReceptorsNuclear Receptors and Signaling

Cited by 491

Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains

Aten, J. A., Stap, J., Krawczyk, P. M., van Oven, C. H., Hoebe, R. A., Essers, J., & Kanaar, R. (2004) · Science

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 491

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Gusev, A., Mancuso, N., Won, H., Kousi, M., Finucane, H. K., Reshef, Y., Song, L., Safi, A., Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll, S., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 491

Intrinsic and extrinsic mechanisms regulating satellite cell function

Dumont, N. A., Wang, Y. X., & Rudnicki, M. A. (2015) · Development

Muscle Physiology and DisordersCongenital heart defects research

Cited by 491

A meta-analysis of diabetes mellitus and the risk of prostate cancer

Kasper, J. S., & Giovannucci, E. (2006) · Cancer Epidemiology, Biomarkers & Prevention

Metabolism, Diabetes, and CancerProstate Cancer Treatment and Research

Cited by 491

Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation

Chen, C., Liao, J., Xia, Y., Liu, X., Jones, R., Haran, J., McCormick, B., Sampson, T. R., Alam, A., & Ye, K. (2022) · Gut

Gut microbiota and healthAlzheimer's disease research and treatments

Cited by 491

Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

Sack, J. S., Kish, K. F., Wang, C., Attar, R. M., Kiefer, S. E., An, Y., Wu, G. Y., Scheffler, J. E., Salvati, M. E., Krystek, S. R., et al. (2001) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

Cited by 491

Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA

Briggs, A. W., Stenzel, U., Meyer, M., Krause, J., Kircher, M., & Pääbo, S. (2010) · Nucleic Acids Research

Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology

Cited by 491

Stress hormone-mediated invasion of ovarian cancer cells

Sood, A. K., Bhatty, R., Kamat, A. A., Landen, C. N., Han, L., Thaker, P. H., Li, Y., Gershenson, D. M., Lutgendorf, S., & Cole, S. W. (2006) · Clinical Cancer Research

Cancer, Stress, Anesthesia, and Immune ResponseOvarian cancer diagnosis and treatment

Cited by 491

METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation

Pandolfini, L., Barbieri, I., Bannister, A. J., Hendrick, A., Andrews, B., Webster, N., Murat, P., Mach, P., Brandi, R., Robson, S. C., et al. (2019) · Molecular Cell

RNA modifications and cancerRNA regulation and disease

Cited by 491

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts

Waterman-Storer, C. M., Worthylake, R. A., Liu, B. P., Burridge, K., & Salmon, E. D. (1999) · Nature Cell Biology

Cellular Mechanics and InteractionsMicrotubule and mitosis dynamics

Cited by 491

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

Xie, Z., Lau, K., Eby, B., Lozano, P., He, C., Pennington, B., Li, H., Rathi, S., Dong, Y., Tian, R., et al. (2011) · Diabetes

Autophagy in Disease and TherapyCardiovascular Function and Risk Factors

Cited by 490

Control of confounding of genetic associations in stratified populations

Hoggart, C. J., Parra, E. J., Shriver, M. D., Bonilla, C., Kittles, R. A., Clayton, D. G., & McKeigue, P. M. (2003) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 490

Genomic and biochemical insights into the specificity of ETS transcription factors

Hollenhorst, P. C., McIntosh, L. P., & Graves, B. J. (2011) · Annual Review of Biochemistry

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 490

Generation and assembly of human brain region-specific three-dimensional cultures

Sloan, S. A., Andersen, J., Pașca, A. M., Birey, F., & Pașca, S. P. (2018) · Nature Protocols

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 490

Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1

Vakoc, C. R., Letting, D. L., Gheldof, N., Sawado, T., Bender, M. A., Groudine, M., Weiss, M. J., Dekker, J., & Blobel, G. A. (2005) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 490

Microdiesel: Escherichia coli engineered for fuel production

Kalscheuer, R., Stölting, T., & Steinbüchel, A. (2006) · Microbiology

Microbial Metabolic Engineering and BioproductionLipid metabolism and biosynthesis

Cited by 490

Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging

Terman, A., Kurz, T., Navratil, M., Arriaga, E. A., & Brunk, U. T. (2010) · Antioxidants & Redox Signaling

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 490

Analysis of the Adult Human Plasma Metabolome

Lawton, K. A., Berger, A., Mitchell, M., Milgram, K. E., Evans, A. M., Guo, L., Hanson, R. W., Kalhan, S. C., Ryals, J. A., & Milburn, M. V. (2008) · Pharmacogenomics

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 490

Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation

Sun, Q., Burke, J. P., Phan, J., Burns, M. C., Olejniczak, E. T., Waterson, A. G., Lee, T., Rossanese, O. W., & Fesik, S. W. (2012) · Angewandte Chemie International Edition

Protein Kinase Regulation and GTPase SignalingComputational Drug Discovery Methods

Cited by 490