Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Buckley, D. L., Raina, K., Darricarrere, N., Hines, J., Gustafson, J. L., Smith, I. E., Miah, A. H., Harling, J. D., & Crews, C. M. (2015) · ACS Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 488

M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124

Song, Y., Li, Z., He, T., Qu, M., Jiang, L., Li, W., Shi, X., Pan, J., Zhang, L., Wang, Y., et al. (2019) · Theranostics

Extracellular vesicles in diseaseNeuroinflammation and Neurodegeneration Mechanisms

Cited by 487

Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species

Buffenstein, R. (2008) · Journal of Comparative Physiology B

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 487

Dissecting eIF4E action in tumorigenesis

Wendel, H.-G., Silva, R. L. A., Malina, A., Mills, J. R., Zhu, H., Ueda, T., Watanabe-Fukunaga, R., Fukunaga, R., Teruya-Feldstein, J., Pelletier, J., et al. (2007) · Genes & Development

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

Cited by 487

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

Kim, Y.-B., Nikoulina, S. E., Ciaraldi, T. P., Henry, R. R., & Kahn, B. B. (1999) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 487

The repertoire of glycan determinants in the human glycome

Cummings, R. D. (2009) · Molecular BioSystems

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 487

A population genetic signal of polygenic adaptation

Berg, J. J., & Coop, G. (2014) · PLoS Genetics

Genetic diversity and population structureForensic and Genetic Research

Cited by 487

Studies of Photosynthesis Using a Pulsed Laser

De Vault, D., & Chance, B. (1966) · Biophysical Journal

Photosynthetic Processes and MechanismsPhotochemistry and Electron Transfer Studies

Cited by 487

Metformin Inhibits Cytokine-Induced Nuclear Factor κB Activation Via AMP-Activated Protein Kinase Activation in Vascular Endothelial Cells

Hattori, Y., Suzuki, K., Hattori, S., & Kasai, K. (2006) · Hypertension

Metabolism, Diabetes, and CancerNF-κB Signaling Pathways

Cited by 487

The emerging landscape of breast cancer susceptibility

Stratton, M. R., & Rahman, N. (2008) · Nature Genetics

BRCA gene mutations in cancerGenetic Associations and Epidemiology

Cited by 487

Self-amplifying RNA vaccines for infectious diseases

Bloom, K., van den Berg, F., & Arbuthnot, P. (2021) · Gene Therapy

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 487

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., He, J., Fan, D., Fowdar, J., Kennedy, M., et al. (2019) · Genome Medicine

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 487

Scaffolding protein functional sites using deep learning

Wang, J., Lisanza, S., Juergens, D., Tischer, D., Watson, J. L., Castro, K. M., Ragotte, R., Saragovi, A., Milles, L. F., Baek, M., et al. (2022) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 487

Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

Suberbielle, E., Sanchez, P. E., Kravitz, A. V., Wang, X., Ho, K., Eilertson, K., Devidze, N., Kreitzer, A. C., & Mucke, L. (2013) · Nature Neuroscience

DNA Repair MechanismsAlzheimer's disease research and treatments

Cited by 487

Variation in the mutation rate across mammalian genomes

Hodgkinson, A., & Eyre-Walker, A. (2011) · Nature Reviews Genetics

Evolution and Genetic DynamicsCancer Genomics and Diagnostics

Cited by 487

Exploiting the critical perioperative period to improve long-term cancer outcomes

Horowitz, M., Neeman, E., Sharon, E., & Ben-Eliyahu, S. (2015) · Nature Reviews Clinical Oncology

Cancer, Stress, Anesthesia, and Immune ResponseEnhanced Recovery After Surgery

Cited by 487

Analysis of Gut Microbiota in Patients with Parkinson’s Disease

Petrov, V. A., Saltykova, I. V., Zhukova, I. A., Alifirova, V. M., Zhukova, N. G., Dorofeeva, Y. B., Tyakht, A. V., Kovarsky, B. A., Alekseev, D. G., Kostryukova, E. S., et al. (2017) · Bulletin of Experimental Biology and Medicine

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 487

Optimal ancient DNA yields from the inner ear part of the human petrous bone

Pinhasi, R., Fernandes, D., Sirak, K., Novak, M., Connell, S., Alpaslan-Roodenberg, S., Gerritsen, F., Moiseyev, V., Gromov, A., Raczky, P., et al. (2015) · PLoS ONE

Forensic and Genetic ResearchPaleopathology and ancient diseases

Cited by 487

Sulfonation and molecular action

Strott, C. A. (2002) · Endocrine Reviews

Estrogen and related hormone effectsReceptor Mechanisms and Signaling

Cited by 487

New recombinant serotypes of AAV vectors

Gao, G., Vandenberghe, L., & Wilson, J. (2005) · Current Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 487

Transcription-coupled nucleotide excision repair in mammalian cells: Molecular mechanisms and biological effects

Fousteri, M., & Mullenders, L. H. (2008) · Cell Research

DNA Repair MechanismsNuclear Structure and Function

Cited by 487

Phase I study of GC1008 (fresolimumab): a human anti‐transforming growth factor‐beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

Morris, J. C., Tan, A. R., Olencki, T. E., Shapiro, G. I., Dezube, B. J., Reiss, M., Hsu, F. J., Berzofsky, J. A., & Lawrence, D. P. (2014) · PLoS ONE

TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers

Cited by 487

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

DeSelm, C. J., Miller, B. C., Zou, W., Beatty, W. L., van Meel, E., Takahata, Y., Klumperman, J., Tooze, S. A., Teitelbaum, S. L., & Virgin, H. W. (2011) · Developmental Cell

Bone Metabolism and DiseasesAutophagy in Disease and Therapy

Cited by 487

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Zhang, X., Crowley, V. M., Wucherpfennig, T. G., Dix, M. M., & Cravatt, B. F. (2019) · Nature Chemical Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 487