Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Development of targeted protein degradation therapeutics

Chamberlain, P. P., & Hamann, L. G. (2019) · Nature Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 489

Good cop, bad cop: the different faces of NF-κB

Perkins, N. D., & Gilmore, T. D. (2006) · Cell Death & Differentiation

NF-κB Signaling PathwaysSignaling Pathways in Disease

Cited by 489

Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae

Jordá, T., & Puig, S. (2020) · Genes

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 489

MEC-17 is an α-tubulin acetyltransferase

Akella, J. S., Wloga, D., Kim, J., Starostina, N. G., Lyons-Abbott, S., Morrissette, N. S., Dougan, S. T., Kipreos, E. T., & Gaertig, J. (2010) · Nature

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 489

P2X 7 Receptor-Mediated Release of Excitatory Amino Acids from Astrocytes

Duan, S., Anderson, C. M., Keung, E. C., Chen, Y., Chen, Y., & Swanson, R. A. (2003) · The Journal of Neuroscience

Adenosine and Purinergic SignalingNeuroscience and Neuropharmacology Research

Cited by 489

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Verfaillie, A., Imrichova, H., Atak, Z. K., Dewaele, M., Rambow, F., Hulselmans, G., Christiaens, V., Svetlichnyy, D., Luciani, F., Van den Mooter, L., et al. (2015) · Nature Communications

Melanoma and MAPK PathwaysGenomics and Chromatin Dynamics

Cited by 489

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Guenther, M. G., Lane, W. S., Fischle, W., Verdin, E., Lazar, M. A., & Shiekhattar, R. (2000) · Genes & Development

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 489

Epigenetics and cancer

Lund, A. H., & van Lohuizen, M. (2004) · Genes & Development

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 489

Activating SRC mutation in a subset of advanced human colon cancers

Irby, R. B., Mao, W., Coppola, D., Kang, J., Loubeau, J. M., Trudeau, W., Karl, R., Fujita, D. J., Jove, R., & Yeatman, T. J. (1999) · Nature Genetics

Protein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy

Cited by 489

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

Papandreou, I., Denko, N. C., Olson, M., Van Melckebeke, H., Lust, S., Tam, A., Solow-Cordero, D. E., Bouley, D. M., Offner, F., Niwa, M., et al. (2011) · Blood

Endoplasmic Reticulum Stress and DiseaseMultiple Myeloma Research and Treatments

Cited by 489

Normally occurring environmental and behavioral influences on gene activity: From central dogma to probabilistic epigenesis

Gottlieb, G. (1998) · Psychological Review

Epigenetics and DNA MethylationPhilosophy of Biology and Scientific Explanation

Cited by 489

Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

Holmes, B. F., Kurth-Kraczek, E. J., & Winder, W. W. (1999) · Journal of Applied Physiology

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 489

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

Nault, J.-C., Datta, S., Imbeaud, S., Franconi, A., Mallet, M., Couchy, G., Letouzé, E., Pilati, C., Verret, B., Blanc, J.-F., et al. (2015) · Nature Genetics

Virus-based gene therapy researchCancer Genomics and Diagnostics

Cited by 489

The ancestral and industrialized gut microbiota and implications for human health

Sonnenburg, E. D., & Sonnenburg, J. L. (2019) · Nature Reviews Microbiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 489

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

Michalon, A., Sidorov, M., Ballard, T. M., Ozmen, L., Spooren, W., Wettstein, J. G., Jaeschke, G., Bear, M. F., & Lindemann, L. (2012) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 489

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Bayraktar, O. A., Bartels, T., Holmqvist, S., Kleshchevnikov, V., Martirosyan, A., Polioudakis, D., Ben Haim, L., Young, A. M. H., Batiuk, M. Y., Prakash, K., et al. (2020) · Nature Neuroscience

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 489

PER2 controls lipid metabolism by direct regulation of PPARγ

Grimaldi, B., Bellet, M. M., Katada, S., Astarita, G., Hirayama, J., Amin, R. H., Granneman, J. G., Piomelli, D., Leff, T., & Sassone-Corsi, P. (2010) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsCircadian rhythm and melatonin

Cited by 489

Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly

Verdijk, L. B., Koopman, R., Schaart, G., Meijer, K., Savelberg, H. H. C. M., & van Loon, L. J. C. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 489

Role of membrane potential in the regulation of cell proliferation and differentiation

Sundelacruz, S., Levin, M., & Kaplan, D. L. (2009) · Stem Cell Reviews and Reports

Planarian Biology and ElectrostimulationDevelopmental Biology and Gene Regulation

Cited by 489

Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA

Sawyer, S., Krause, J., Guschanski, K., Savolainen, V., & Pääbo, S. (2012) · PLoS ONE

Forensic and Genetic ResearchArchaeology and ancient environmental studies

Cited by 489

A gut-derived metabolite alters brain activity and anxiety behaviour in mice

Needham, B. D., Funabashi, M., Adame, M. D., Wang, Z., Boktor, J. C., Haney, J., Wu, W.-L., Rabut, C., Ladinsky, M. S., Hwang, S.-J., et al. (2022) · Nature

Gut microbiota and healthTryptophan and brain disorders

Cited by 489

A 2-year randomized controlled trial of human caloric restriction: Feasibility and effects on predictors of health span and longevity

Ravussin, E., Redman, L. M., Rochon, J., Das, S. K., Fontana, L., Kraus, W. E., Romashkan, S., Williamson, D. A., Meydani, S. N., Villareal, D. T., et al. (2015) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 489

Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy

Duan, D. (2018) · Molecular Therapy

Virus-based gene therapy researchNeurogenetic and Muscular Disorders Research

Cited by 489

De novo mutations of SETBP1 cause Schinzel-Giedion syndrome

Hoischen, A., van Bon, B. W. M., Gilissen, C., Arts, P., van Lier, B., Steehouwer, M., de Vries, P., de Reuver, R., Wieskamp, N., Mortier, G., et al. (2010) · Nature Genetics

Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders

Cited by 489