Most cited biochemistry, genetics and molecular biology papers
- Verified
Deep learning in microscopy image analysis: a survey
Xing, F., Xie, Y., Su, H., Liu, F., & Yang, L. (2018) · IEEE Transactions on Neural Networks and Learning Systems
Cell Image Analysis TechniquesAdvanced Neural Network Applications
Cited by 460
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Effective gene therapy with nonintegrating lentiviral vectors
Yáñez-Muñoz, R. J., Balaggan, K. S., MacNeil, A., Howe, S. J., Schmidt, M., Smith, A. J., Buch, P., MacLaren, R. E., Anderson, P. N., Barker, S. E., et al. (2006) · Nature Medicine
Virus-based gene therapy researchRetinal Development and Disorders
Cited by 460
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A highlight on Sonic hedgehog pathway
Carballo, G. B., Honorato, J. R., de Lopes, G. P. F., & Spohr, T. C. L. D. S. E. (2018) · Cell Communication and Signaling
Hedgehog Signaling Pathway StudiesGlioma Diagnosis and Treatment
Cited by 460
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Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis.
Gutierrez, L., Magee, A. I., Marshall, C. J., & Hancock, J. F. (1989) · The EMBO Journal
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 460
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The endothelial glycocalyx: a review of the vascular barrier
Alphonsus, C. S., & Rodseth, R. N. (2014) · Anaesthesia
Proteoglycans and glycosaminoglycans researchNitric Oxide and Endothelin Effects
Cited by 460
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DockQ: A Quality Measure for Protein-Protein Docking Models
Basu, S., & Wallner, B. (2016) · PLOS ONE
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 460
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Genetic Diversity and Conservation Units: Dealing With the Species-Population Continuum in the Age of Genomics
Coates, D. J., Byrne, M., & Moritz, C. (2018) · Frontiers in Ecology and Evolution
Genetic diversity and population structureConservation, Ecology, Wildlife Education
Cited by 460
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Cerberus-like is a secreted factor with neuralizing activity expressed in the anterior primitive endoderm of the mouse gastrula
Belo, J. A., Bouwmeester, T., Leyns, L., Kertesz, N., Gallo, M., Follettie, M., & De Robertis, E. M. (1997) · Mechanisms of Development
Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer
Cited by 460
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Engineering bacteria for diagnostic and therapeutic applications
Riglar, D. T., & Silver, P. A. (2018) · Nature Reviews Microbiology
Bacterial Cancer TherapyMicrobial Metabolic Engineering and Bioproduction
Cited by 460
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Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention
Virág, L., Szabó, É., Gergely, P., & Szabó, C. (2003) · Toxicology Letters
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 460
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Deep learning of the tissue-regulated splicing code
Leung, M. K. K., Xiong, H. Y., Lee, L. J., & Frey, B. J. (2014) · Bioinformatics
RNA Research and SplicingGenomics and Phylogenetic Studies
Cited by 459
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Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
Zhang, P., Behre, G., Pan, J., Iwama, A., Wara-aswapati, N., Radomska, H. S., Auron, P. E., Tenen, D. G., & Sun, Z. (1999) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation
Cited by 459
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Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme
Cho, U. S., & Xu, W. (2007) · Nature
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 459
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Dicarbonyl Intermediates in the Maillard Reaction
THORNALLEY, P. J. (2005) · Annals of the New York Academy of Sciences
Advanced Glycation End Products researchPotato Plant Research
Cited by 459
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Integrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases
Sun, Y. V., & Hu, Y.-J. (2016) · Advances in Genetics
Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology
Cited by 459
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Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer
Pate, K. T., Stringari, C., Sprowl‐Tanio, S., Wang, K., TeSlaa, T., Hoverter, N. P., McQuade, M. M., Garner, C., Digman, M. A., Teitell, M. A., et al. (2014) · The EMBO Journal
Cancer, Hypoxia, and MetabolismWnt/β-catenin signaling in development and cancer
Cited by 459
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Dense sampling of bird diversity increases power of comparative genomics
Feng, S., Stiller, J., Deng, Y., Armstrong, J., Fang, Q., Reeve, A. H., Xie, D., Chen, G., Guo, C., Faircloth, B. C., et al. (2020) · Nature
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 459
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Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization
Finn, E. H., Pegoraro, G., Brandão, H. B., Valton, A.-L., Oomen, M. E., Dekker, J., Mirny, L., & Misteli, T. (2019) · Cell
Genomics and Chromatin DynamicsNuclear Structure and Function
Cited by 459
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Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Chen, Z.-H., Kim, H. P., Sciurba, F. C., Lee, S.-J., Feghali-Bostwick, C., Stolz, D. B., Dhir, R., Landreneau, R. J., Schuchert, M. J., Yousem, S. A., et al. (2008) · PLoS ONE
Autophagy in Disease and TherapyChronic Obstructive Pulmonary Disease (COPD) Research
Cited by 459
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Glutaminolysis as a target for cancer therapy
Jin, L., Alesi, G. N., & Kang, S. (2016) · Oncogene
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 459
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Ecological speciation in sticklebacks: environment-dependent hybrid fitness
Hatfield, T., & Schluter, D. (1999) · Evolution
Evolution and Genetic DynamicsAnimal Behavior and Reproduction
Cited by 459
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Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
De Cecco, M., Criscione, S. W., Peckham, E. J., Hillenmeyer, S., Hamm, E. A., Manivannan, J., Peterson, A. L., Kreiling, J. A., Neretti, N., & Sedivy, J. M. (2013) · Aging Cell
Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics
Cited by 459
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Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution
Li, B., Zhang, W., Guo, C., Xu, H., Li, L., Fang, M., Hu, Y., Zhang, X., Yao, X., Tang, M., et al. (2022) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 459
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Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli
Sklar, J. G., Wu, T., Kahne, D., & Silhavy, T. J. (2007) · Genes & Development
Heat shock proteins researchBacterial Genetics and Biotechnology
Cited by 459
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