Most cited biochemistry, genetics and molecular biology papers
- Verified
Biologically informed deep neural network for prostate cancer discovery
Elmarakeby, H. A., Hwang, J., Arafeh, R., Crowdis, J., Gang, S., Liu, D., AlDubayan, S. H., Salari, K., Kregel, S., Richter, C., et al. (2021) · Nature
Prostate Cancer Treatment and ResearchRadiomics and Machine Learning in Medical Imaging
Cited by 456
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Continuity in evolution: on the nature of transitions.
Fontana, W., & Schuster, P. (1998) · Science
Evolution and Genetic DynamicsRNA and protein synthesis mechanisms
Cited by 456
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Locus control regions
Li, Q., Peterson, K. R., Fang, X., & Stamatoyannopoulos, G. (2002) · Blood
Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders
Cited by 456
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Mechanisms and functions of ribosome-associated protein quality control
Joazeiro, C. A. P. (2019) · Nature Reviews Molecular Cell Biology
RNA and protein synthesis mechanismsUbiquitin and proteasome pathways
Cited by 456
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Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells
Bakshi, S., Siryaporn, A., Goulian, M., & Weisshaar, J. C. (2012) · Molecular Microbiology
RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology
Cited by 456
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Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans
Barbieri, M., Bonafè, M., Franceschi, C., & Paolisso, G. (2003) · American Journal of Physiology-Endocrinology and Metabolism
Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer
Cited by 456
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Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells
Guenther, M. G., Frampton, G. M., Soldner, F., Hockemeyer, D., Mitalipova, M., Jaenisch, R., & Young, R. A. (2010) · Cell Stem Cell
Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics
Cited by 456
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cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data
Bravo González-Blas, C., Minnoye, L., Papasokrati, D., Aibar, S., Hulselmans, G., Christiaens, V., Davie, K., Wouters, J., & Aerts, S. (2019) · Nature Methods
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 456
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Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
Matsunaga, K., Morita, E., Saitoh, T., Akira, S., Ktistakis, N. T., Izumi, T., Noda, T., & Yoshimori, T. (2010) · Journal of Cell Biology
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 456
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SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age
Van Meter, M., Kashyap, M., Rezazadeh, S., Geneva, A. J., Morello, T. D., Seluanov, A., & Gorbunova, V. (2014) · Nature Communications
Chromosomal and Genetic VariationsSirtuins and Resveratrol in Medicine
Cited by 456
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The intestinal microbiota regulates body composition through NFIL3 and the circadian clock
Wang, Y., Kuang, Z., Yu, X., Ruhn, K. A., Kubo, M., & Hooper, L. V. (2017) · Science
Gut microbiota and healthCircadian rhythm and melatonin
Cited by 456
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Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome
Mars, R. A. T., Yang, Y., Ward, T., Houtti, M., Priya, S., Lekatz, H. R., Tang, X., Sun, Z., Kalari, K. R., Korem, T., et al. (2020) · Cell
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 456
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Widespread Genomic Signatures of Natural Selection in Hominid Evolution
McVicker, G., Gordon, D., Davis, C., & Green, P. (2009) · PLoS Genetics
Evolution and Genetic DynamicsForensic and Genetic Research
Cited by 456
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Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
Houde, V. P., Brûlé, S., Festuccia, W. T., Blanchard, P.-G., Bellmann, K., Deshaies, Y., & Marette, A. (2010) · Diabetes
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 456
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Histochemical and enzymatic comparison of the gastrocnemius muscle of young and elderly men and women
Coggan, A. R., Spina, R. J., King, D. S., Rogers, M. A., Rogers, M. A., Brown, M., Nemeth, P. M., & Holloszy, J. O. (1992) · Journal of Gerontology
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 456
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Transgenerational transmission of environmental information in C. elegans
Klosin, A., Casas, E., Hidalgo-Carcedo, C., Vavouri, T., & Lehner, B. (2017) · Science
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 456
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Desensitization of neuronal nicotinic receptors
Quick, M. W., & Lester, R. A. J. (2002) · Journal of Neurobiology
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 456
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Dietary effects on human gut microbiome diversity
Xu, Z., & Knight, R. (2015) · British Journal Of Nutrition
Gut microbiota and healthNutritional Studies and Diet
Cited by 456
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False discovery rate, sensitivity and sample size for microarray studies
Pawitan, Y., Michiels, S., Koscielny, S., Gusnanto, A., & Ploner, A. (2005) · Bioinformatics
Gene expression and cancer classificationStatistical Methods in Clinical Trials
Cited by 455
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The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
Pich, S., Bach, D., Briones, P., Liesa, M., Camps, M., Testar, X., Palacín, M., & Zorzano, A. (2005) · Human Molecular Genetics
Mitochondrial Function and PathologyHereditary Neurological Disorders
Cited by 455
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Small molecules enhance CRISPR genome editing in pluripotent stem cells
Yu, C., Liu, Y., Ma, T., Liu, K., Xu, S., Zhang, Y., Liu, H., La Russa, M., Xie, M., Ding, S., et al. (2015) · Cell stem cell
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 455
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Comprehensive analysis of single cell ATAC-seq data with SnapATAC
Fang, R., Preissl, S., Li, Y., Hou, X., Lucero, J., Wang, X., Motamedi, A., Shiau, A. K., Zhou, X., Xie, F., et al. (2021) · Nature Communications
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 455
- Verified
Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes
Hannon, E., Lunnon, K., Schalkwyk, L., & Mill, J. (2015) · Epigenetics
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 455
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Understanding network concepts in modules
Dong, J., & Horvath, S. (2007) · BMC Systems Biology
Bioinformatics and Genomic NetworksComplex Network Analysis Techniques
Cited by 455
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