Most cited biochemistry, genetics and molecular biology papers
- Verified
JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia
Bonetto, A., Aydogdu, T., Jin, X., Zhang, Z., Zhan, R., Puzis, L., Koniaris, L. G., & Zimmers, T. A. (2012) · American Journal of Physiology-Endocrinology and Metabolism
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 463
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BET Proteins as Targets for Anticancer Treatment
Stathis, A., & Bertoni, F. (2018) · Cancer Discovery
Protein Degradation and InhibitorsChromatin Remodeling and Cancer
Cited by 463
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MicroRNA expression in the adult mouse central nervous system
Bak, M., Silahtaroglu, A., Møller, M., Christensen, M., Rath, M. F., Skryabin, B., Tommerup, N., & Kauppinen, S. (2008) · RNA
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 463
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Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation
Dong, X. C., Copps, K. D., Guo, S., Li, Y., Kollipara, R., DePinho, R. A., & White, M. F. (2008) · Cell Metabolism
FOXO transcription factor regulationMetabolism, Diabetes, and Cancer
Cited by 463
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Evolution of Transcription Factor Binding Sites in Mammalian Gene Regulatory Regions: Conservation and Turnover
Dermitzakis, E. T., & Clark, A. G. (2002) · Molecular Biology and Evolution
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 463
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Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
Stewart, D., Killeen, E., Naquin, R., Alam, S., & Alam, J. (2003) · Journal of Biological Chemistry
Genomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon Monoxide
Cited by 463
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Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and -independent approaches
Krebs, M. G., Hou, J.-M., Sloane, R., Lancashire, L., Priest, L., Nonaka, D., Ward, T. H., Backen, A., Clack, G., Hughes, A., et al. (2012) · Journal of Thoracic Oncology
Cancer Genomics and DiagnosticsCancer Cells and Metastasis
Cited by 463
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Multiple Functions of Peroxiredoxins: Peroxidases, Sensors and Regulators of the Intracellular Messenger H 2 O 2 , and Protein Chaperones
Rhee, S. G., & Woo, H. A. (2011) · Antioxidants & Redox Signaling
Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 463
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Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
Aragane, Y., Kulms, D., Metze, D., Wilkes, G., Pöppelmann, B., Luger, T. A., & Schwarz, T. (1998) · The Journal of Cell Biology
Cell death mechanisms and regulationSkin Protection and Aging
Cited by 463
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A Conserved Hox Axis in the Mouse and Human Female Reproductive System: Late Establishment and Persistent Adult Expression of the Hoxa Cluster Genes
Taylor, H. S., Vanden Heuvel, G. B., & Igarashi, P. (1997) · Biology of Reproduction
Developmental Biology and Gene RegulationGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Cited by 463
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Replication and protection of telomeres
Verdun, R. E., & Karlseder, J. (2007) · Nature
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 463
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Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
Segrè, A. V., DIAGRAM Consortium, MAGIC investigators, Groop, L., Mootha, V. K., Daly, M. J., & Altshuler, D. (2010) · PLoS Genetics
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 463
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Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi
Dadachova, E., Bryan, R. A., Huang, X., Moadel, T., Schweitzer, A. D., Aisen, P., Nosanchuk, J. D., & Casadevall, A. (2007) · PLoS ONE
melanin and skin pigmentationEffects of Radiation Exposure
Cited by 463
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Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma, A., Huffman, J. E., Rodriguez, A., Conery, M., Liu, M., Ho, Y.-L., Kim, Y., Heise, D. A., Guare, L., Panickan, V. A., et al. (2024) · Science
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 463
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Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities
Wondrak, G. T. (2009) · Antioxidants & Redox Signaling
Redox biology and oxidative stressBioactive Compounds and Antitumor Agents
Cited by 462
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Identification of androgen receptors in normal human osteoblast-like cells.
Colvard, D. S., Eriksen, E. F., Keeting, P. E., Wilson, E. M., Lubahn, D. B., French, F. S., Riggs, B. L., & Spelsberg, T. C. (1989) · Proceedings of the National Academy of Sciences
Estrogen and related hormone effectsBone Metabolism and Diseases
Cited by 462
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NF-κB inhibition delays DNA damage–induced senescence and aging in mice
Tilstra, J. S., Robinson, A. R., Wang, J., Gregg, S. Q., Clauson, C. L., Reay, D. P., Nasto, L. A., St Croix, C. M., Usas, A., Vo, N., et al. (2012) · Journal of Clinical Investigation
Genetics, Aging, and Longevity in Model OrganismsNF-κB Signaling Pathways
Cited by 462
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Glucocorticoids promote breast cancer metastasis
Obradović, M. M. S., Hamelin, B., Manevski, N., Couto, J. P., Sethi, A., Coissieux, M.-M., Münst, S., Okamoto, R., Kohler, H., Schmidt, A., et al. (2019) · Nature
Estrogen and related hormone effectsCancer, Stress, Anesthesia, and Immune Response
Cited by 462
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Cancer-associated adipocytes: key players in breast cancer progression
Wu, Q., Li, B., Li, Z., Li, J., Sun, S., & Sun, S. (2019) · Journal of Hematology & Oncology
Cancer, Lipids, and MetabolismAdipokines, Inflammation, and Metabolic Diseases
Cited by 462
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Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
Jacquemont, S., Reymond, A., Zufferey, F., Harewood, L., Walters, R. G., Kutalik, Z., Martinet, D., Shen, Y., Valsesia, A., Beckmann, N. D., et al. (2011) · Nature
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 462
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NGL Viewer: a web application for molecular visualization
Rose, A. S., & Hildebrand, P. W. (2015) · Nucleic Acids Research
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 462
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Differentiation therapy revisited
de Thé, H. (2018) · Nature reviews. Cancer
Retinoids in leukemia and cellular processesAcute Myeloid Leukemia Research
Cited by 462
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Essential role of limiting telomeres in the pathogenesis of Werner syndrome
Chang, S., Multani, A. S., Cabrera, N. G., Naylor, M. L., Laud, P., Lombard, D., Pathak, S., Guarente, L., & DePinho, R. A. (2004) · Nature Genetics
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 462
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Functional Synergy and Physical Interactions of the Erythroid Transcription Factor GATA-1 with the Krüppel Family Proteins Sp1 and EKLF
Merika, M., & Orkin, S. H. (1995) · Molecular and Cellular Biology
Kruppel-like factors researchGenomics and Chromatin Dynamics
Cited by 462
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