Most cited biochemistry, genetics and molecular biology papers
- Verified
Mitochondria and cell signalling
Tait, S. W. G., & Green, D. R. (2012) · Journal of Cell Science
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 453
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The lipid biochemistry of eukaryotic algae
Li-Beisson, Y., Thelen, J. J., Fedosejevs, E., & Harwood, J. L. (2019) · Progress in Lipid Research
Lipid metabolism and biosynthesisAlgal biology and biofuel production
Cited by 453
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Cholesterol homeostasis and function in neurons of the central nervous system
Pfrieger, F. W. (2003) · Cellular and Molecular Life Sciences
Cholesterol and Lipid MetabolismNeuroscience and Neuropharmacology Research
Cited by 453
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Geographic Patterns of Genome Admixture in Latin American Mestizos
Wang, S., Ray, N., Rojas, W., Parra, M. V., Bedoya, G., Gallo, C., Poletti, G., Mazzotti, G., Hill, K., Hurtado, A. M., et al. (2008) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 453
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Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients
Befroy, D. E., Petersen, K. F., Dufour, S., Mason, G. F., de Graaf, R. A., Rothman, D. L., & Shulman, G. I. (2007) · Diabetes
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 453
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Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications
Cerneckis, J., Cai, H., & Shi, Y. (2024) · Signal Transduction and Targeted Therapy
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 452
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Oncogenic Isocitrate Dehydrogenase Mutations: Mechanisms, Models, and Clinical Opportunities
Cairns, R. A., & Mak, T. W. (2013) · Cancer Discovery
Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment
Cited by 452
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Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
Tzung, S.-P., Kim, K. M., Basañez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y. J., & Hockenbery, D. M. (2001) · Nature Cell Biology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 452
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Alterations of the microRNA network cause neurodegenerative disease
Hébert, S. S., & De Strooper, B. (2009) · Trends in Neurosciences
MicroRNA in disease regulationNeuroinflammation and Neurodegeneration Mechanisms
Cited by 452
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Am I ready for CRISPR? A user's guide to genetic screens
Doench, J. G. (2018) · Nature Reviews Genetics
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 452
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Defining the genetic, genomic, cellular, and diagnostic architectures of psychiatric disorders
Sullivan, P. F., & Geschwind, D. H. (2019) · Cell
Genetic Associations and EpidemiologySchizophrenia research and treatment
Cited by 452
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Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone.
Zhang, J., Dai, J., Qi, Y., Lin, D.-L., Smith, P., Strayhorn, C., Mizokami, A., Fu, Z., Westman, J., & Keller, E. T. (2001) · Journal of Clinical Investigation
Bone Metabolism and DiseasesBone health and treatments
Cited by 452
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Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
Armanios, M., Chen, J.-L., Chang, Y.-P. C., Brodsky, R. A., Hawkins, A., Griffin, C. A., Eshleman, J. R., Cohen, A. R., Chakravarti, A., Hamosh, A., et al. (2005) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceBlood disorders and treatments
Cited by 452
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Dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus
Wang, J., Zheng, J., Shi, W., Du, N., Xu, X., Zhang, Y., Ji, P., Zhang, F., Jia, Z., Wang, Y., et al. (2018) · Gut
Gut microbiota and healthGestational Diabetes Research and Management
Cited by 452
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Metabolism and Metabolic Disorders and the Microbiome: The Intestinal Microbiota Associated With Obesity, Lipid Metabolism, and Metabolic Health—Pathophysiology and Therapeutic Strategies
Aron-Wisnewsky, J., Warmbrunn, M. V., Nieuwdorp, M., & Clément, K. (2021) · Gastroenterology
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 452
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A melanocyte lineage program confers resistance to MAP kinase pathway inhibition
Johannessen, C. M., Johnson, L. A., Piccioni, F., Townes, A., Frederick, D. T., Donahue, M. K., Narayan, R., Flaherty, K. T., Wargo, J. A., Root, D. E., et al. (2013) · Nature
Melanoma and MAPK PathwaysProtein Tyrosine Phosphatases
Cited by 452
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The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
Zhou, N., Jiang, Y., Bergquist, T. R., Lee, A. J., Kacsoh, B. Z., Crocker, A. W., Lewis, K. A., Georghiou, G., Nguyen, H. N., Hamid, M. N., et al. (2019) · Genome Biology
Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies
Cited by 452
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Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
Hu, B., Elinav, E., Huber, S., Booth, C. J., Strowig, T., Jin, C., Eisenbarth, S. C., & Flavell, R. A. (2010) · Proceedings of the National Academy of Sciences
Inflammasome and immune disordersCell death mechanisms and regulation
Cited by 452
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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
Ng, B., White, C. C., Klein, H.-U., Sieberts, S. K., McCabe, C., Patrick, E., Xu, J., Yu, L., Gaiteri, C., Bennett, D. A., et al. (2017) · Nature Neuroscience
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 452
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Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1
Verhoog, L., Brekelmans, C., Seynaeve, C., van den Bosch, L., Dahmen, G., van Geel, A., Tilanus-Linthorst, M., Bartels, C., Wagner, A., van den Ouweland, A., et al. (1998) · The Lancet
BRCA gene mutations in cancerBreast Lesions and Carcinomas
Cited by 452
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Use of allele scores as instrumental variables for Mendelian randomization
Burgess, S., & Thompson, S. G. (2013) · International Journal of Epidemiology
Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques
Cited by 452
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Modeling the interactions between osteoblast and osteoclast activities in bone remodeling
Lemaire, V., Tobin, F. L., Greller, L. D., Cho, C. R., & Suva, L. J. (2004) · Journal of Theoretical Biology
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 452
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Human heart-forming organoids recapitulate early heart and foregut development
Drakhlis, L., Biswanath, S., Farr, C.-M., Lupanow, V., Teske, J., Ritzenhoff, K., Franke, A., Manstein, F., Bolesani, E., Kempf, H., et al. (2021) · Nature Biotechnology
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 452
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Integrative detection and analysis of structural variation in cancer genomes
Dixon, J. R., Xu, J., Dileep, V., Zhan, Y., Song, F., Le, V. T., Yardımcı, G. G., Chakraborty, A., Bann, D. V., Wang, Y., et al. (2018) · Nature Genetics
Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics
Cited by 452
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