Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

Pattanayak, V., Ramirez, C. L., Joung, J. K., & Liu, D. R. (2011) · Nature Methods

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 453

Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoproterenol.

Simpson, P., & Savion, S. (1982) · Circulation Research

Congenital heart defects researchCardiac electrophysiology and arrhythmias

Cited by 453

Novel therapies emerging in oncology to target the TGF‐β pathway

Kim, B.-G., Malek, E., Choi, S. H., Ignatz-Hoover, J. J., & Driscoll, J. J. (2021) · Journal of Hematology & Oncology

TGF-β signaling in diseasesKruppel-like factors research

Cited by 453

Mechanism of action of niacin

Kamanna, V. S., & Kashyap, M. L. (2008) · The American Journal of Cardiology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 453

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

Park, J. O., Rubin, S. A., Xu, Y.-F., Amador-Noguez, D., Fan, J., Shlomi, T., & Rabinowitz, J. D. (2016) · Nature Chemical Biology

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 453

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Gomez-Sanchez, J. A., Carty, L., Iruarrizaga-Lejarreta, M., Palomo-Irigoyen, M., Varela-Rey, M., Griffith, M., Hantke, J., Macias-Camara, N., Azkargorta, M., Aurrekoetxea, I., et al. (2015) · Journal of Cell Biology

Autophagy in Disease and TherapyNerve injury and regeneration

Cited by 453

Supervised Machine Learning for Population Genetics: A New Paradigm

Schrider, D. R., & Kern, A. D. (2018) · Trends in Genetics

Genetic diversity and population structureGenomics and Phylogenetic Studies

Cited by 453

W hats H ap : Weighted Haplotype Assembly for Future-Generation Sequencing Reads

Patterson, M., Marschall, T., Pisanti, N., van Iersel, L., Stougie, L., Klau, G. W., & Schönhuth, A. (2015) · Journal of Computational Biology

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 453

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

Bakhoum, S. F., Thompson, S. L., Manning, A. L., & Compton, D. A. (2009) · Nature Cell Biology

Microtubule and mitosis dynamicsDNA Repair Mechanisms

Cited by 453

Metabolomics: A Primer

Liu, X., & Locasale, J. W. (2017) · Trends in Biochemical Sciences

Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and Applications

Cited by 453

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles

Tang, K., Zhang, Y., Zhang, H., Xu, P., Liu, J., Ma, J., Lv, M., Li, D., Katirai, F., Shen, G.-X., et al. (2012) · Nature Communications

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 453

Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation

Roth, J. (1985) · Cell

Glycosylation and Glycoproteins ResearchCellular transport and secretion

Cited by 453

Innate immunity and inflammation in ageing: a key for understanding age-related diseases

Licastro, F., Candore, G., Lio, D., Porcellini, E., Colonna-Romano, G., Franceschi, C., & Caruso, C. (2005) · Immunity & Ageing

Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation

Cited by 453

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

Tumaneng, K., Schlegelmilch, K., Russell, R. C., Yimlamai, D., Basnet, H., Mahadevan, N., Fitamant, J., Bardeesy, N., Camargo, F. D., & Guan, K.-L. (2012) · Nature Cell Biology

Hippo pathway signaling and YAP/TAZPI3K/AKT/mTOR signaling in cancer

Cited by 453

The Gene Expression Program of Prostate Fibroblast Senescence Modulates Neoplastic Epithelial Cell Proliferation through Paracrine Mechanisms

Bavik, C., Coleman, I., Dean, J. P., Knudsen, B., Plymate, S., & Nelson, P. S. (2006) · Cancer Research

Telomeres, Telomerase, and SenescenceProstate Cancer Treatment and Research

Cited by 453

The genetic consequences of habitat fragmentation

Templeton, A. R., Shaw, K., Routman, E., & Davis, S. K. (1990) · Annals of the Missouri Botanical Garden

Genetic diversity and population structureEcology and Vegetation Dynamics Studies

Cited by 453

Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung

Schupp, J. C., Adams, T. S., Cosme, C., Raredon, M. S. B., Yuan, Y., Omote, N., Poli, S., Chioccioli, M., Rose, K.-A., Manning, E. P., et al. (2021) · Circulation

Single-cell and spatial transcriptomicsPulmonary Hypertension Research and Treatments

Cited by 453

Allostery: Absence of a change in shape does not imply that allostery is not at play

Tsai, C.-J., del Sol, A., & Nussinov, R. (2008) · Journal of Molecular Biology

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 453

Massively parallel de novo protein design for targeted therapeutics

Chevalier, A., Silva, D.-A., Rocklin, G. J., Hicks, D. R., Vergara, R., Murapa, P., Bernard, S. M., Zhang, L., Lam, K.-H., Yao, G., et al. (2017) · Nature

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 453

What is Bioinformatics? A Proposed Definition and Overview of the Field

Luscombe, N. M., Greenbaum, D., & Gerstein, M. (2001) · Methods of Information in Medicine

Genetics, Bioinformatics, and Biomedical ResearchGenomics and Phylogenetic Studies

Cited by 453

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

Cheng, L., Ding, G., Qin, Q., Huang, Y., Lewis, W., He, N., Evans, R. M., Schneider, M. D., Brako, F. A., Xiao, Y., et al. (2004) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 453

Organization and Function of Membrane Contact Sites

Helle, S. C. J., Kanfer, G., Kolar, K., Lang, A., Michel, A. H., & Kornmann, B. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Cellular transport and secretionIon Channels and Receptors

Cited by 453

Brefeldin A Acts to Stabilize an Abortive ARF–GDP–Sec7 Domain Protein Complex

Peyroche, A., Antonny, B., Robineau, S., Acker, J., Cherfils, J., & Jackson, C. L. (1999) · Molecular Cell

Cellular transport and secretionFungal and yeast genetics research

Cited by 453

Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections

Mazmanian, S. K., Liu, G., Jensen, E. R., Lenoy, E., & Schneewind, O. (2000) · Proceedings of the National Academy of Sciences

Biochemical and Structural CharacterizationAntimicrobial Resistance in Staphylococcus

Cited by 453