Most cited biochemistry, genetics and molecular biology papers
- Verified
PTOP interacts with POT1 and regulates its localization to telomeres
Liu, D., Safari, A., O'Connor, M. S., Chan, D. W., Laegeler, A., Qin, J., & Songyang, Z. (2004) · Nature Cell Biology
Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry
Cited by 450
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Interactions of the Low Density Lipoprotein Receptor Gene Family with Cytosolic Adaptor and Scaffold Proteins Suggest Diverse Biological Functions in Cellular Communication and Signal Transduction
Gotthardt, M., Trommsdorff, M., Nevitt, M. F., Shelton, J., Richardson, J. A., Stockinger, W., Nimpf, J., & Herz, J. (2000) · Journal of Biological Chemistry
Cholesterol and Lipid MetabolismReceptor Mechanisms and Signaling
Cited by 450
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Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
Jucker, M., & Walker, L. C. (2018) · Nature Neuroscience
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 450
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The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
Zhang, S., Hulver, M. W., McMillan, R. P., Cline, M. A., & Gilbert, E. R. (2014) · Nutrition & Metabolism
Biochemical Acid Research StudiesMetabolism, Diabetes, and Cancer
Cited by 450
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A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
Gupta, R. M., Hadaya, J., Trehan, A., Zekavat, S. M., Roselli, C., Klarin, D., Emdin, C. A., Hilvering, C. R. E., Bianchi, V., Mueller, C., et al. (2017) · Cell
Genetic Associations and EpidemiologyCerebrovascular and genetic disorders
Cited by 450
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Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review
Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology
Metabolomics and Mass Spectrometry StudiesAdrenal Hormones and Disorders
Cited by 450
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The gut microbiota in human energy homeostasis and obesity
Rosenbaum, M., Knight, R., & Leibel, R. L. (2015) · Trends in Endocrinology & Metabolism
Gut microbiota and healthRegulation of Appetite and Obesity
Cited by 450
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Parthanatos, a messenger of death
David, K. K. (2009) · Frontiers in Bioscience
Cell death mechanisms and regulationPARP inhibition in cancer therapy
Cited by 450
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Epigenetic mechanisms in neurological disease
Jakovcevski, M., & Akbarian, S. (2012) · Nature Medicine
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 450
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Targeted Degradation of Oncogenic KRAS G12C by VHL-Recruiting PROTACs
Bond, M. J., Chu, L., Nalawansha, D. A., Li, K., & Crews, C. M. (2020) · ACS Central Science
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 450
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Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
Broer, L., Codd, V., Nyholt, D. R., Deelen, J., Mangino, M., Willemsen, G., Albrecht, E., Amin, N., Beekman, M., de Geus, E. J. C., et al. (2013) · European Journal of Human Genetics
Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology
Cited by 450
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PPARγ as a new therapeutic target in inflammatory bowel diseases
Dubuquoy, L., Rousseaux, C., Thuru, X., Peyrin-Biroulet, L., Romano, O., Chavatte, P., Chamaillard, M., & Desreumaux, P. (2006) · Gut
Peroxisome Proliferator-Activated ReceptorsInflammatory Bowel Disease
Cited by 450
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Adaptations of archaeal and bacterial membranes to variations in temperature, pH and pressure
Siliakus, M. F., van der Oost, J., & Kengen, S. W. M. (2017) · Extremophiles
Lipid Membrane Structure and BehaviorBacterial Genetics and Biotechnology
Cited by 450
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Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior
Blundell, J., Blaiss, C. A., Etherton, M. R., Espinosa, F., Tabuchi, K., Walz, C., Bolliger, M. F., Südhof, T. C., & Powell, C. M. (2010) · The Journal of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 450
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Integration of Adeno-Associated Virus (AAV) and Recombinant AAV Vectors
McCarty, D. M., Young, S. M., & Samulski, R. J. (2004) · Annual Review of Genetics
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 450
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Whole population, genome-wide mapping of hidden relatedness
Gusev, A., Lowe, J. K., Stoffel, M., Daly, M. J., Altshuler, D., Breslow, J. L., Friedman, J. M., & Pe'er, I. (2009) · Genome Research
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 450
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HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
Khan, O., & La Thangue, N. B. (2012) · Immunology & Cell Biology
Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation
Cited by 450
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DNA methylation: An epigenetic mark of cellular memory
Kim, M., & Costello, J. (2017) · Experimental & Molecular Medicine
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 450
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Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
An, J., Muoio, D. M., Shiota, M., Fujimoto, Y., Cline, G. W., Shulman, G. I., Koves, T. R., Stevens, R., Millington, D., & Newgard, C. B. (2004) · Nature Medicine
Lipid metabolism and biosynthesisDiet, Metabolism, and Disease
Cited by 450
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Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: Old actors and new players
Yuan, X., Larsson, C., & Xu, D. (2019) · Oncogene
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 450
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Cell aging in relation to stress arousal and cardiovascular disease risk factors
Epel, E. S., Lin, J., Wilhelm, F. H., Wolkowitz, O. M., Cawthon, R., Adler, N. E., Dolbier, C., Mendes, W. B., & Blackburn, E. H. (2006) · Psychoneuroendocrinology
Telomeres, Telomerase, and SenescenceStress Responses and Cortisol
Cited by 450
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TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites
van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., Wulf, P. S., Keijzer, N., Demmers, J., Kapitein, L. C., et al. (2013) · Neuron
Microtubule and mitosis dynamicsMitochondrial Function and Pathology
Cited by 450
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Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders
Psychiatric GWAS Consortium Coordinating Committee (2009) · American Journal of Psychiatry
Genetic Associations and EpidemiologySchizophrenia research and treatment
Cited by 450
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Antimicrobial Tolerance in Biofilms
Stewart, P. S. (2015) · Microbiology Spectrum
Bacterial biofilms and quorum sensingAntimicrobial agents and applications
Cited by 450
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