Most cited biochemistry, genetics and molecular biology papers
- Verified
CRISPR-Mediated Tagging of Endogenous Proteins with a Luminescent Peptide
Schwinn, M. K., Machleidt, T., Zimmerman, K., Eggers, C. T., Dixon, A. S., Hurst, R., Hall, M. P., Encell, L. P., Binkowski, B. F., & Wood, K. V. (2018) · ACS Chemical Biology
bioluminescence and chemiluminescence researchCRISPR and Genetic Engineering
Cited by 434
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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer
Joanito, I., Wirapati, P., Zhao, N., Nawaz, Z., Yeo, G., Lee, F., Eng, C. L. P., Macalinao, D. C., Kahraman, M., Srinivasan, H., et al. (2022) · Nature Genetics
Single-cell and spatial transcriptomicsGenetic factors in colorectal cancer
Cited by 434
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Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities
Ding, X. F., Anderson, C. M., Ma, H., Hong, H., Uht, R. M., Kushner, P. J., & Stallcup, M. R. (1998) · Molecular Endocrinology
Estrogen and related hormone effectsGenomics and Chromatin Dynamics
Cited by 434
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Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
Slobodin, B., Han, R., Calderone, V., Vrielink, J. A. F. O., Loayza-Puch, F., Elkon, R., & Agami, R. (2017) · Cell
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 434
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Synaptic Vesicle Size and Number Are Regulated by a Clathrin Adaptor Protein Required for Endocytosis
Zhang, B., Koh, Y. H., Beckstead, R. B., Budnik, V., Ganetzky, B., & Bellen, H. J. (1998) · Neuron
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 434
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Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
Kavran, J. M., Klein, D. E., Lee, A., Falasca, M., Isakoff, S. J., Skolnik, E. Y., & Lemmon, M. A. (1998) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 434
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The Costs of using Unauthenticated, Over-Passaged Cell Lines: How Much more Data do we Need?
Hughes, P., Marshall, D., Reid, Y., Parkes, H., & Gelber, C. (2007) · BioTechniques
Viral Infectious Diseases and Gene Expression in InsectsAnimal testing and alternatives
Cited by 434
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Structural Insights into Biological Roles of Protein-Glycosaminoglycan Interactions
Raman, R., Sasisekharan, V., & Sasisekharan, R. (2005) · Chemistry & Biology
Proteoglycans and glycosaminoglycans researchPolysaccharides and Plant Cell Walls
Cited by 434
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Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy
Nicot, A.-S., Toussaint, A., Tosch, V., Kretz, C., Wallgren-Pettersson, C., Iwarsson, E., Kingston, H., Garnier, J.-M., Biancalana, V., Oldfors, A., et al. (2007) · Nature Genetics
Muscle Physiology and DisordersGenomics and Rare Diseases
Cited by 434
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An Extremely Potent Inhibitor of Xanthine Oxidoreductase
Okamoto, K., Eger, B. T., Nishino, T., Kondo, S., Pai, E. F., & Nishino, T. (2003) · Journal of Biological Chemistry
Biochemical and Molecular ResearchEnzyme Structure and Function
Cited by 434
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C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms
Tian, Y., Li, Z., Hu, W., Ren, H., Tian, E., Zhao, Y., Lu, Q., Huang, X., Yang, P., Li, X., et al. (2010) · Cell
Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms
Cited by 434
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Tet-On Systems For Doxycycline-inducible Gene Expression
T. Das, A., Tenenbaum, L., & Berkhout, B. (2016) · Current Gene Therapy
Virus-based gene therapy researchCRISPR and Genetic Engineering
Cited by 434
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Tumour-associated mutant p53 drives the Warburg effect
Zhang, C., Liu, J., Liang, Y., Wu, R., Zhao, Y., Hong, X., Lin, M., Yu, H., Liu, L., Levine, A. J., et al. (2013) · Nature Communications
Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Cited by 434
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Adaptive Evolution within Gut Microbiomes of Healthy People
Zhao, S., Lieberman, T. D., Poyet, M., Kauffman, K. M., Gibbons, S. M., Groussin, M., Xavier, R. J., & Alm, E. J. (2019) · Cell Host & Microbe
Gut microbiota and healthEvolution and Genetic Dynamics
Cited by 434
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Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy
Tang, R., Wei, Y., Li, Y., Chen, W., Chen, H., Wang, Q., Yang, F., Miao, Q., Xiao, X., Zhang, H., et al. (2018) · Gut
Gut microbiota and healthLiver Diseases and Immunity
Cited by 434
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A connectionist model of development
Mjolsness, E., Sharp, D. H., & Reinitz, J. (1991) · Journal of Theoretical Biology
Developmental Biology and Gene RegulationGene Regulatory Network Analysis
Cited by 434
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Low-Dose Penicillin in Early Life Induces Long-Term Changes in Murine Gut Microbiota, Brain Cytokines and Behavior
Leclercq, S., Mian, F. M., Stanisz, A. M., Bindels, L. B., Cambier, E., Ben-Amram, H., Koren, O., Forsythe, P., & Bienenstock, J. (2017) · Nature Communications
Gut microbiota and healthTryptophan and brain disorders
Cited by 434
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The promise of N-acetylcysteine in neuropsychiatry
Berk, M., Malhi, G. S., Gray, L. J., & Dean, O. M. (2013) · Trends in Pharmacological Sciences
Sulfur Compounds in BiologyTreatment of Major Depression
Cited by 434
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Genetic architecture: the shape of the genetic contribution to human traits and disease
Timpson, N. J., Greenwood, C. M. T., Soranzo, N., Lawson, D. J., & Richards, J. B. (2018) · Nature Reviews Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 434
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Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress
Tretter, L., & Adam-Vizi, V. (2005) · Philosophical Transactions of the Royal Society B: Biological Sciences
Biochemical Acid Research StudiesMitochondrial Function and Pathology
Cited by 434
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Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal
Jia, J., Claude-Taupin, A., Gu, Y., Choi, S. W., Peters, R., Bissa, B., Mudd, M. H., Allers, L., Pallikkuth, S., Lidke, K. A., et al. (2020) · Developmental Cell
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 434
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Mitochondrial quality control and muscle mass maintenance.
Romanello, V., & Sandri, M. (2016) · Frontiers in Physiology
Muscle Physiology and DisordersMitochondrial Function and Pathology
Cited by 434
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Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS)
Krone, N., Hughes, B. A., Lavery, G. G., Stewart, P. M., Arlt, W., & Shackleton, C. H. L. (2010) · The Journal of Steroid Biochemistry and Molecular Biology
Metabolism and Genetic DisordersMetabolomics and Mass Spectrometry Studies
Cited by 434
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Genetics and the Specificity of the Aging Process
Hekimi, S., & Guarente, L. (2003) · Science
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 434
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