Most cited biochemistry, genetics and molecular biology papers
- Verified
Reverse engineering gene networks: integrating genetic perturbations with dynamical modeling
Tegnér, J., Yeung, M. K. S., Hasty, J., & Collins, J. J. (2003) · Proceedings of the National Academy of Sciences
Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction
Cited by 433
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Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists
Kapadia, R. (2008) · Frontiers in Bioscience
Peroxisome Proliferator-Activated ReceptorsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 433
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Extreme vulnerability of IDH1 mutant cancers to NAD+ depletion
Tateishi, K., Wakimoto, H., Iafrate, A. J., Tanaka, S., Loebel, F., Lelic, N., Wiederschain, D., Bedel, O., Deng, G., Zhang, B., et al. (2015) · Cancer Cell
Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research
Cited by 433
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Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy
Meijer, T. W. H., Kaanders, J. H. A. M., Span, P. N., & Bussink, J. (2012) · Clinical Cancer Research
Cancer, Hypoxia, and MetabolismRadiation Therapy and Dosimetry
Cited by 433
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Unconventional secretion of Acb1 is mediated by autophagosomes
Duran, J. M., Anjard, C., Stefan, C., Loomis, W. F., & Malhotra, V. (2010) · Journal of Cell Biology
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 433
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Crystal structure of a DExx box DNA helicase
Subramanya, H. S., Bird, L. E., Brannigan, J. A., & Wigley, D. B. (1996) · Nature
Enzyme Structure and FunctionDNA Repair Mechanisms
Cited by 433
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The Human Tumor Antigen PRAME Is a Dominant Repressor of Retinoic Acid Receptor Signaling
Epping, M. T., Wang, L., Edel, M. J., Carlée, L., Hernandez, M., & Bernards, R. (2005) · Cell
Retinoids in leukemia and cellular processesEpigenetics and DNA Methylation
Cited by 432
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Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
Wang, Y., An, H., Liu, T., Qin, C., Sesaki, H., Guo, S., Radovick, S., Hussain, M., Maheshwari, A., Wondisford, F. E., et al. (2019) · Cell Reports
Metabolism, Diabetes, and CancerMitochondrial Function and Pathology
Cited by 432
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Structure of activated transcription complex Pol II–DSIF–PAF–SPT6
Vos, S. M., Farnung, L., Boehning, M., Wigge, C., Linden, A., Urlaub, H., & Cramer, P. (2018) · Nature
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 432
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NADPH oxidase in brain injury and neurodegenerative disorders
Ma, M. W., Wang, J., Zhang, Q., Wang, R., Dhandapani, K. M., Vadlamudi, R. K., & Brann, D. W. (2017) · Molecular Neurodegeneration
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 432
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AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies
Caenepeel, S., Brown, S. P., Belmontes, B., Moody, G., Keegan, K. S., Chui, D., Whittington, D. A., Huang, X., Poppe, L., Cheng, A. C., et al. (2018) · Cancer Discovery
Cell death mechanisms and regulationAcute Myeloid Leukemia Research
Cited by 432
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The Glycogen-Binding Domain on the AMPK β Subunit Allows the Kinase to Act as a Glycogen Sensor
McBride, A., Ghilagaber, S., Nikolaev, A., & Hardie, D. G. (2009) · Cell Metabolism
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 432
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Protoplasmic organization of hyphal tips among fungi: vesicles and Spitzenkorper.
Grove, S. N., & Bracker, C. E. (1970) · Journal of Bacteriology
Fungal and yeast genetics researchCellular transport and secretion
Cited by 432
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Effects of p21 Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
Chang, B.-D., Watanabe, K., Broude, E. V., Fang, J., Poole, J. C., Kalinichenko, T. V., & Roninson, I. B. (2000) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 432
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Metabolic signatures of exercise in human plasma
Lewis, G. D., Farrell, L., Wood, M. J., Martinovic, M., Arany, Z., Rowe, G. C., Souza, A., Cheng, S., McCabe, E. L., Yang, E., et al. (2010) · Science Translational Medicine
Metabolomics and Mass Spectrometry StudiesCardiovascular and exercise physiology
Cited by 432
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Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism
Wang, L., Christophersen, C. T., Sorich, M. J., Gerber, J. P., Angley, M. T., & Conlon, M. A. (2011) · Applied and Environmental Microbiology
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 432
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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
Mimura, N., Fulciniti, M., Gorgun, G., Tai, Y.-T., Cirstea, D., Santo, L., Hu, Y., Fabre, C., Minami, J., Ohguchi, H., et al. (2012) · Blood
Endoplasmic Reticulum Stress and DiseaseMultiple Myeloma Research and Treatments
Cited by 432
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Role of Myokines in Regulating Skeletal Muscle Mass and Function
Lee, J. H., & Jun, H.-S. (2019) · Frontiers in Physiology
Muscle Physiology and DisordersExercise and Physiological Responses
Cited by 432
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The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD) 1 1Edited by P. E. Wight
Bateman, A., & Bycroft, M. (2000) · Journal of Molecular Biology
Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization
Cited by 432
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Phylogenomics reveals three sources of adaptive variation during a rapid radiation
Pease, J. B., Haak, D. C., Hahn, M. W., & Moyle, L. C. (2016) · PLOS Biology
Chromosomal and Genetic VariationsPlant Diversity and Evolution
Cited by 432
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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
Chakraborty, A. A., Laukka, T., Myllykoski, M., Ringel, A. E., Booker, M. A., Tolstorukov, M. Y., Meng, Y. J., Meier, S. R., Jennings, R. B., Creech, A. L., et al. (2019) · Science
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 432
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Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
Spradlin, J. N., Hu, X., Ward, C. C., Brittain, S. M., Jones, M. D., Ou, L., To, M., Proudfoot, A., Ornelas, E., Woldegiorgis, M., et al. (2019) · Nature Chemical Biology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 432
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Intracellular localisation of human HIF-1α hydroxylases:implications for oxygen sensing
Metzen, E., Berchner-Pfannschmidt, U., Stengel, P., Marxsen, J. H., Stolze, I., Klinger, M., Huang, W. Q., Wotzlaw, C., Hellwig-Bürgel, T., Jelkmann, W., et al. (2003) · Journal of Cell Science
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 432
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Autophagy is required for exercise training‐induced skeletal muscle adaptation and improvement of physical performance
Lira, V. A., Okutsu, M., Zhang, M., Greene, N. P., Laker, R. C., Breen, D. S., Hoehn, K. L., & Yan, Z. (2013) · The FASEB Journal
Autophagy in Disease and TherapyMuscle Physiology and Disorders
Cited by 432
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