Most cited biochemistry, genetics and molecular biology papers
- Verified
Metabolic Inflexibility: When Mitochondrial Indecision Leads to Metabolic Gridlock
Muoio, D. M. (2014) · Cell
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 438
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Targeted protein degradation: from mechanisms to clinic
Tsai, J. M., Nowak, R. P., Ebert, B. L., & Fischer, E. S. (2024) · Nature Reviews Molecular Cell Biology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 438
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Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription
Takahashi, H., McCaffery, J. M., Irizarry, R. A., & Boeke, J. D. (2006) · Molecular Cell
Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research
Cited by 438
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CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors
Vora, S. R., Juric, D., Kim, N., Mino-Kenudson, M., Huynh, T., Costa, C., Lockerman, E. L., Pollack, S. F., Liu, M., Li, X., et al. (2014) · Cancer Cell
PI3K/AKT/mTOR signaling in cancerAdvanced Breast Cancer Therapies
Cited by 438
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Effect of hydrogen peroxide and dithiothreitol on contractile function of single skeletal muscle fibres from the mouse
Andrade, F. H., Reid, M. B., Allen, D. G., & Westerblad, H. (1998) · The Journal of Physiology
Redox biology and oxidative stressMuscle Physiology and Disorders
Cited by 438
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The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis
Yu, Z., Luo, H., Fu, W., & Mattson, M. P. (1999) · Experimental Neurology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 438
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Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
Smith, L. L., Coller, H. A., & Roberts, J. M. (2003) · Nature Cell Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 438
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Histone H3 Lysine 4 Demethylation Is a Target of Nonselective Antidepressive Medications
Lee, M. G., Wynder, C., Schmidt, D. M., McCafferty, D. G., & Shiekhattar, R. (2006) · Chemistry & Biology
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 438
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Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways
A., K., & J., P. (2002) · Diabetologia
Metabolism, Diabetes, and CancerCaveolin-1 and cellular processes
Cited by 438
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Stalk Model of Membrane Fusion: Solution of Energy Crisis
Kozlovsky, Y., & Kozlov, M. M. (2002) · Biophysical Journal
Lipid Membrane Structure and BehaviorCellular transport and secretion
Cited by 438
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Fluorescence Correlation Spectroscopy: Past, Present, Future
Elson, E. L. (2011) · Biophysical Journal
Advanced Fluorescence Microscopy TechniquesDiffusion Coefficients in Liquids
Cited by 438
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Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation
Moxon, R., Bayliss, C., & Hood, D. (2006) · Annual Review of Genetics
Bacterial Genetics and BiotechnologyEvolution and Genetic Dynamics
Cited by 438
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The Gut Microbial Endocrine Organ: Bacterially Derived Signals Driving Cardiometabolic Diseases
Brown, J. M., & Hazen, S. L. (2015) · Annual Review of Medicine
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 438
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The exocyst complex in polarized exocytosis
He, B., & Guo, W. (2009) · Current Opinion in Cell Biology
Cellular transport and secretionExtracellular vesicles in disease
Cited by 438
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TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress
Raben, N., & Puertollano, R. (2016) · Annual Review of Cell and Developmental Biology
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 437
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Mitochondrial function and apoptotic susceptibility in aging skeletal muscle
Chabi, B., Ljubicic, V., Menzies, K. J., Huang, J. H., Saleem, A., & Hood, D. A. (2008) · Aging Cell
Mitochondrial Function and PathologyMuscle Physiology and Disorders
Cited by 437
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Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
Jin, S.-G., Kadam, S., & Pfeifer, G. P. (2010) · Nucleic Acids Research
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 437
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Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
Cazet, A. S., Hui, M. N., Elsworth, B. L., Wu, S. Z., Roden, D., Chan, C.-L., Skhinas, J. N., Collot, R., Yang, J., Harvey, K., et al. (2018) · Nature Communications
Hedgehog Signaling Pathway StudiesCancer Cells and Metastasis
Cited by 437
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An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities
Kaminsky, E. B., Kaul, V., Paschall, J., Church, D. M., Bunke, B., Kunig, D., Moreno-De-Luca, D., Moreno-De-Luca, A., Mulle, J. G., Warren, S. T., et al. (2011) · Genetics in Medicine
Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases
Cited by 437
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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
Tresse, E., Salomons, F. A., Vesa, J., Bott, L. C., Kimonis, V., Yao, T.-P., Dantuma, N. P., & Taylor, J. P. (2010) · Autophagy
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 437
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The molecular inflammatory process in aging
Chung, H. Y., Sung, B., Jung, K. J., Zou, Y., & Yu, B. P. (2006) · Antioxidants & Redox Signaling
Genetics, Aging, and Longevity in Model OrganismsNF-κB Signaling Pathways
Cited by 437
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The central role of muscle stem cells in regenerative failure with aging
Blau, H. M., Cosgrove, B. D., & Ho, A. T. V. (2015) · Nature Medicine
Muscle Physiology and DisordersMesenchymal stem cell research
Cited by 437
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Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
Zhou, H., Su, J., Hu, X., Zhou, C., Li, H., Chen, Z., Xiao, Q., Wang, B., Wu, W., Sun, Y., et al. (2020) · Cell
CRISPR and Genetic EngineeringRetinal Development and Disorders
Cited by 437
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Systematic interpretation of genetic interactions using protein networks
Kelley, R., & Ideker, T. (2005) · Nature Biotechnology
Bioinformatics and Genomic NetworksFungal and yeast genetics research
Cited by 437
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