Most cited biochemistry, genetics and molecular biology papers
- Verified
Essential Role of p38 Mitogen-activated Protein Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1
Matsumoto, M., Kogawa, M., Wada, S., Takayanagi, H., Tsujimoto, M., Katayama, S., Hisatake, K., & Nogi, Y. (2004) · Journal of Biological Chemistry
Bone Metabolism and DiseasesSignaling Pathways in Disease
Cited by 436
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Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes
Cox, D., Chang, P., Zhang, Q., Reddy, P. G., Bokoch, G. M., & Greenberg, S. (1997) · The Journal of Experimental Medicine
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 436
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Presynaptic activity regulates Na+ channel distribution at the axon initial segment
Kuba, H., Oichi, Y., & Ohmori, H. (2010) · Nature
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 436
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Amino acids and mTORC1: from lysosomes to disease
Efeyan, A., Zoncu, R., & Sabatini, D. M. (2012) · Trends in Molecular Medicine
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 436
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Sunlight damage to cellular DNA: focus on oxidatively generated lesions
Schuch, A. P., Moreno, N. C., Schuch, N. J., Menck, C. F. M., & Garcia, C. C. M. (2017) · Free Radical Biology and Medicine
DNA Repair MechanismsSkin Protection and Aging
Cited by 436
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Evidence for Gradients of Human Genetic Diversity Within and Among Continents
Serre, D., & Pääbo, S. (2004) · Genome Research
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 436
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Identification of Genetic Variants That Affect Histone Modifications in Human Cells
McVicker, G., van de Geijn, B., Degner, J. F., Cain, C. E., Banovich, N. E., Raj, A., Lewellen, N., Myrthil, M., Gilad, Y., & Pritchard, J. K. (2013) · Science
Genomics and Chromatin DynamicsGenetic Associations and Epidemiology
Cited by 436
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Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB
Frede, S., Stockmann, C., Freitag, P., & Fandrey, J. (2006) · Biochemical Journal
Cancer, Hypoxia, and MetabolismImmune Response and Inflammation
Cited by 436
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Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration
Rusmini, P., Cortese, K., Crippa, V., Cristofani, R., Cicardi, M. E., Ferrari, V., Vezzoli, G., Tedesco, B., Meroni, M., Messi, E., et al. (2019) · Autophagy
Autophagy in Disease and TherapyAmyotrophic Lateral Sclerosis Research
Cited by 436
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The human glucocorticoid receptor: molecular basis of biologic function
Nicolaides, N. C., Galata, Z., Kino, T., Chrousos, G. P., & Charmandari, E. (2010) · Steroids
Estrogen and related hormone effectsGenomics and Chromatin Dynamics
Cited by 436
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The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
Martini-Stoica, H., Xu, Y., Ballabio, A., & Zheng, H. (2016) · Trends in Neurosciences
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 436
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Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
Chipuk, J. E., McStay, G. P., Bharti, A., Kuwana, T., Clarke, C. J., Siskind, L. J., Obeid, L. M., & Green, D. R. (2012) · Cell
Cell death mechanisms and regulationSphingolipid Metabolism and Signaling
Cited by 436
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Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell
Wei, G., Xi, W., Nussinov, R., & Ma, B. (2016) · Chemical Reviews
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 436
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RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
Xie, Y., & Varshavsky, A. (2001) · Proceedings of the National Academy of Sciences
Ubiquitin and proteasome pathwaysHeat shock proteins research
Cited by 436
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MicroRNA profiling of the murine hematopoietic system
Monticelli, S., Ansel, K. M., Xiao, C., Socci, N. D., Krichevsky, A. M., Thai, T.-H., Rajewsky, N., Marks, D. S., Sander, C., Rajewsky, K., et al. (2005) · Genome Biology
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 436
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Absence of intestinal microbiota does not protect mice from diet-induced obesity
Fleissner, C. K., Huebel, N., Abd El-Bary, M. M., Loh, G., Klaus, S., & Blaut, M. (2010) · British Journal of Nutrition
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 436
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Methodological challenges in utilizing mi RNA s as circulating biomarkers
Moldovan, L., Batte, K. E., Trgovcich, J., Wisler, J., Marsh, C. B., & Piper, M. (2014) · Journal of Cellular and Molecular Medicine
MicroRNA in disease regulationExtracellular vesicles in disease
Cited by 436
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How does the oxidative burst of macrophages kill bacteria? Still an open question
Slauch, J. M. (2011) · Molecular Microbiology
Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 436
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Incidence of Fragile X Syndrome by Newborn Screening for Methylated FMR1 DNA
Coffee, B., Keith, K., Albizua, I., Malone, T., Mowrey, J., Sherman, S. L., & Warren, S. T. (2009) · The American Journal of Human Genetics
Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases
Cited by 436
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Inferring biological networks by sparse identification of nonlinear dynamics
Mangan, N. M., Brunton, S. L., Proctor, J. L., & Kutz, J. N. (2016) · IEEE Transactions on Molecular, Biological and Multi-Scale Communications
Gene Regulatory Network AnalysisControl Systems and Identification
Cited by 436
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Assessing bioenergetic function in response to oxidative stress by metabolic profiling
Dranka, B. P., Benavides, G. A., Diers, A. R., Giordano, S., Zelickson, B. R., Reily, C., Zou, L., Chatham, J. C., Hill, B. G., Zhang, J., et al. (2011) · Free Radical Biology and Medicine
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 436
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Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
London, S. J., Yuan, J.-M., Chung, F.-L., Gao, Y.-T., Coetzee, G. A., Ross, R. K., & Yu, M. C. (2000) · The Lancet
Glutathione Transferases and PolymorphismsGenomics, phytochemicals, and oxidative stress
Cited by 436
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Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion
Bhattarai, Y., Williams, B. B., Battaglioli, E. J., Whitaker, W. R., Till, L., Grover, M., Linden, D. R., Akiba, Y., Kandimalla, K. K., Zachos, N. C., et al. (2018) · Cell Host & Microbe
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 436
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Multiplex assessment of protein variant abundance by massively parallel sequencing
Matreyek, K. A., Starita, L. M., Stephany, J. J., Martin, B., Chiasson, M. A., Gray, V. E., Kircher, M., Khechaduri, A., Dines, J. N., Hause, R. J., et al. (2018) · Nature Genetics
Genomics and Rare DiseasesCancer Genomics and Diagnostics
Cited by 436
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