A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

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Controlling Bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution

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DNA methylation signatures in peripheral blood strongly predict all-cause mortality

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Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

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DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

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Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility

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Blood Epigenetic Age may Predict Cancer Incidence and Mortality

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Epigenetic-based age acceleration in a representative sample of older Americans: Associations with aging-related morbidity and mortality

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Epismoker: A Robust Classifier to Determine Smoking Status from DNA Methylation Data

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Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence

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Identifying mislabeled and contaminated DNA methylation microarray data: an extended quality control toolset with examples from GEO

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Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement

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Refining epigenetic prediction of chronological and biological age

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DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

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Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study

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Translational Perspective on Epigenetics in Cardiovascular Disease

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Adjusting for Batch Effects in DNA Methylation Microarray Data, a Lesson Learned

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Education and lifestyle factors are associated with DNA methylation clocks in older African Americans

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Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease

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Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans

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Identification of rare de novo epigenetic variations in congenital disorders

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Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing

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Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals

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Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

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The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers

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New targeted approaches for epigenetic age predictions

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Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study

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Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross-sectional and longitudinal data

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Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study

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An Epigenome-Wide Association Study of Obesity-Related Traits

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Occupational exposure to pesticides is associated with differential DNA methylation

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Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus

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Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure

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Meta-analyses identify DNA methylation associated with kidney function and damage

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Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

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Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney

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Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

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Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood

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A survey of inter-individual variation in DNA methylation identifies environmentally responsive co-regulated networks of epigenetic variation in the human genome

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DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up

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CoMeBack: DNA methylation array data analysis for co-methylated regions

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Identical twins carry a persistent epigenetic signature of early genome programming

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A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes

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Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures

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Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality

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Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time

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BayesCCE: a Bayesian framework for estimating cell-type composition from DNA methylation without the need for methylation reference

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Epigenome-wide association analysis revealed that SOCS3 methylation influences the effect of cumulative stress on obesity

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Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

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Cell Type–Specific Methylome-wide Association Studies Implicate Neurotrophin and Innate Immune Signaling in Major Depressive Disorder

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Epigenome-wide association study reveals methylation pathways associated with childhood allergic sensitization

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Duration of breastfeeding is associated with leptin (LEP) DNA methylation profiles and BMI in 10-year-old children

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An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

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DNA Methylation Trajectories During Pregnancy

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An epigenome-wide association study of metabolic syndrome and its components

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DunedinPACE: A DNA methylation biomarker of the Pace of AgingPreprint

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Variability of multi-omics profiles in a population-based child cohort

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Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts

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Attention, cognitive control and motivation in ADHD: Linking event-related brain potentials and DNA methylation patterns in boys at early school age

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Comparative epigenome analysis using Infinium DNA methylation BeadChips

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Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development

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DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty

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Association between depression and epigenetic age acceleration: A co‐twin control study

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Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes

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Accurate age prediction from blood using a small set of DNA methylation sites and a cohort-based machine learning algorithm

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Best practices in DNA methylation: lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis

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Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission

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Cross‐tissue comparison of epigenetic aging clocks in humans

Apsley, A. T., Ye, Q., Caspi, A., Chiaro, C. R., Etzel, L. C., Hastings, W. J., Heim, C. C., Kozlosky, J. T., Noll, J. G., Schreier, H. M. C., et al. (2025) · Aging Cell · doi:10.1111/acel.14451 · Cited by 41 · see citing works

Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival

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IgG glycosylation and DNA methylation are interconnected with smoking

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Genome-wide methylation profiling in granulosa lutein cells of women with polycystic ovary syndrome (PCOS)

Makrinou, E., Drong, A., Christopoulos, G., Lerner, A., Chapa-Chorda, I., Karaderi, T., Lavery, S. A., Hardy, K., Lindgren, C. M., & Franks, S. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2019.110611 · Cited by 42 · see citing works

Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

Smith, J. A., Raisky, J., Ratliff, S. M., Liu, J., Kardia, S. L. R., Turner, S. T., Mosley, T. H., & Zhao, W. (2019) · BMC Medical Genomics · doi:10.1186/s12920-019-0585-5 · Cited by 42 · see citing works

In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children

Vives-Usano, M., Hernandéz-Ferrer, C., Maître, L., Ruiz-Arenas, C., Andrušaitytė, S., Borràs, E., Carracedo, Á., Casas, M., Chatzi, L., Coen, M., et al. (2020) · BMC Medicine · doi:10.1186/s12916-020-01686-8 · Cited by 39 · see citing works

Assessing ZNF154 methylation in patient plasma as a multicancer marker in liquid biopsies from colon, liver, ovarian and pancreatic cancer patients

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Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum

Zillich, L., Poisel, E., Frank, J., Foo, J. C., Friske, M. M., Streit, F., Sirignano, L., Heilmann‐Heimbach, S., Heimbach, A., Hoffmann, P., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01959-1 · Cited by 38 · see citing works

DNA methylation and allergic sensitizations: A genome‐scale longitudinal study during adolescence

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OUP accepted manuscript

Gatev, E., Inkster, A. M., Negri, G. L., Konwar, C., Lussier, A. A., Skakkebaek, A. H., Sokolowski, M. B., Gravholt, C. H., Dunn, E. C., Kobor, M. S., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab682 · Cited by 39 · see citing works

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Oriol-Tordera, B., Berdasco, M., Llano, A., Mothe, B., Gálvez, C., Martínez‐Picado, J., Carrillo, J., Blanco, J., Duran-Castells, C., Ganoza, C., et al. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008678 · Cited by 37 · see citing works

Epigenome-wide association study of alcohol use disorder in five brain regions

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Data Analysis of DNA Methylation Epigenome-Wide Association Studies (EWAS): A Guide to the Principles of Best Practice

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DNA methylation signatures analysis with Illumina Infinitum MethylationEPIC and Infinium Human Methylation 450K BeadChip

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DNA Methylation: Methods and Analyses

Gorrie-Stone, T. J. (2019) · Open Access at Essex (University of Essex)

Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data

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Comparison of Illumina Infinium 450K Methylation Bead-Chip preprocessing methods in an Epigenome Wide Association Study

Brucato, M. F., Sobreira, N. L. D. M., Zhang, L., Ladd‐Acosta, C., Ongaco, C. M., Romm, J., Baker, M., Doheny, K. F., Bertola, D. R., Kim, C. A., et al. (2015)