Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
AI on drugs: can artificial intelligence accelerate drug development? Evidence from a large-scale examination of bio-Pharma firms
Lou, B., & Wu, L. (2021) · MIS Quarterly
Computational Drug Discovery MethodsInnovation and Knowledge Management
Cited by 177
- Verified · note
Brief Communication: Better Ways To Question Patients about Adverse Medical Events: A Randomized, Controlled Trial
Bent, S., Padula, A., & Avins, A. L. (2006) · Annals of Internal Medicine
Pharmacovigilance and Adverse Drug ReactionsStatistical Methods in Clinical Trials
Cited by 177
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Generative machine learning for de novo drug discovery: A systematic review
Martinelli, D. D. (2022) · Computers in Biology and Medicine
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 177
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Postmortem toxicology
Skopp, G. (2010) · Forensic Science, Medicine, and Pathology
Forensic Toxicology and Drug AnalysisAutopsy Techniques and Outcomes
Cited by 176
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Protein–polymer conjugation — moving beyond PEGylation
Qi, Y., & Chilkoti, A. (2015) · Current Opinion in Chemical Biology
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 176
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In vitro antifungal activity of hydroxychavicol isolated from Piper betle L
Ali, I., Khan, F. G., Suri, K. A., Gupta, B. D., Satti, N. K., Dutt, P., Afrin, F., Qazi, G. N., & Khan, I. A. (2010) · Annals of Clinical Microbiology and Antimicrobials
Piperaceae Chemical and Biological StudiesEssential Oils and Antimicrobial Activity
Cited by 176
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Proteochemometric modeling as a tool to design selective compounds and for extrapolating to novel targets
van Westen, G. J. P., Wegner, J. K., IJzerman, A. P., van Vlijmen, H. W. T., & Bender, A. (2011) · MedChemComm
Computational Drug Discovery MethodsProtein Interaction Studies and Fluorescence Analysis
Cited by 176
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Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure
James, L. P., Letzig, L., Simpson, P. M., Capparelli, E., Roberts, D. W., Hinson, J. A., Davern, T. J., & Lee, W. M. (2009) · Drug Metabolism and Disposition
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 175
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Common pitfalls in preclinical cancer target validation
Kaelin, W. G. (2017) · Nature Reviews Cancer
Computational Drug Discovery MethodsCancer Mechanisms and Therapy
Cited by 175
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Nanotherapy for posterior eye diseases
Kaur, I. P., & Kakkar, S. (2014) · Journal of Controlled Release
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 175
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Sulfamethoxazole is metabolized to the hydroxylamine in humans
Cribb, A. E., & Spielberg, S. P. (1992) · Clinical Pharmacology and Therapeutics
Pharmacogenetics and Drug MetabolismDrug-Induced Adverse Reactions
Cited by 175
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Investigating the movement of intravitreal human serum albumin nanoparticles in the vitreous and retina
Kim, H., Robinson, S. B., & Csaky, K. G. (2009) · Pharmaceutical Research
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 174
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The role of aldehyde oxidase in drug metabolism
Garattini, E., & Terao, M. (2012) · Expert Opinion on Drug Metabolism & Toxicology
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 174
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Recent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations
Koo, J., Lim, C., & Oh, K. T. (2024) · International Journal of Nanomedicine
Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery
Cited by 174
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Lasers and microdermabrasion enhance and control topical delivery of vitamin C
Lee, W.-R., Shen, S.-C., Wang, K.-H., Hu, C.-H., & Fang, J.-Y. (2003) · Journal of Investigative Dermatology
Advancements in Transdermal Drug DeliveryDermatologic Treatments and Research
Cited by 174
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Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively
Wen, X., Wang, J.-S., Backman, J. T., Laitila, J., & Neuvonen, P. J. (2002) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 173
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Lipid-lowering agents that cause drug-induced hepatotoxicity.
Bhardwaj, S. S., & Chalasani, N. (2007) · Clinics in Liver Disease
Drug-Induced Hepatotoxicity and ProtectionLiver Disease Diagnosis and Treatment
Cited by 173
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Drug Metabolism in Older People--A Key Consideration in Achieving Optimal Outcomes With Medicines
McLachlan, A. J., & Pont, L. G. (2012) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Pharmacogenetics and Drug MetabolismPharmaceutical Practices and Patient Outcomes
Cited by 172
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Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics
Vorrink, S. U., Ullah, S., Schmidt, S., Nandania, J., Velagapudi, V., Beck, O., Ingelman‐Sundberg, M., & Lauschke, V. M. (2017) · The FASEB Journal
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 172
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Quantitative structure-activity relationships and the unnamed science
Hansch, C. (1993) · Accounts of Chemical Research
Computational Drug Discovery MethodsProtein Interaction Studies and Fluorescence Analysis
Cited by 172
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Combination chemical genetics
Lehár, J., Stockwell, B. R., Giaever, G., & Nislow, C. (2008) · Nature Chemical Biology
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 172
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Low density of sigma1 receptors in early Alzheimer’s disease
Mishina, M., Ohyama, M., Ishii, K., Kitamura, S., Kimura, Y., Oda, K.-I., Kawamura, K., Sasaki, T., Kobayashi, S., Katayama, Y., et al. (2008) · Annals of Nuclear Medicine
Pharmacological Receptor Mechanisms and EffectsDementia and Cognitive Impairment Research
Cited by 172
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Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: A technical note
Merchant, H. A., Shoaib, H. M., Tazeen, J., & Yousuf, R. I. (2006) · AAPS PharmSciTech
Advanced Drug Delivery SystemsDrug Solubulity and Delivery Systems
Cited by 171
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Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin
Kivistö, K. T., Kantola, T., & Neuvonen, P. J. (1998) · British Journal of Clinical Pharmacology
Pharmacogenetics and Drug MetabolismLipoproteins and Cardiovascular Health
Cited by 171
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