Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review
Luo, Y., Thompson, W. K., Herr, T. M., Zeng, Z., Berendsen, M. A., Jonnalagadda, S. R., Carson, M. B., & Starren, J. (2017) · Drug Safety
Pharmacovigilance and Adverse Drug ReactionsBiomedical Text Mining and Ontologies
Cited by 200
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Evaluation and optimization of virtual screening workflows with DEKOIS 2.0 – A public library of challenging docking benchmark sets.
Bauer, M. R., Ibrahim, T. M., Vogel, S. M., & Boeckler, F. M. (2013) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsProtein Degradation and Inhibitors
Cited by 200
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Competency of different cell models to predict human hepatotoxic drugs
Gómez-Lechón, M. J., Tolosa, L., Conde, I., & Donato, M. T. (2014) · Expert Opinion on Drug Metabolism & Toxicology
Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives
Cited by 199
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Drug permeability profiling using cell-free permeation tools: overview and applications
Berben, P., Bauer-Brandl, A., Brandl, M., Faller, B., Flaten, G. E., Jacobsen, A.-C., Brouwers, J., & Augustijns, P. (2018) · European Journal of Pharmaceutical Sciences
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 199
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Sex-specific differences in CYP450 isoforms in humans
Scandlyn, M. J., Stuart, E. C., & Rosengren, R. J. (2008) · Expert Opinion on Drug Metabolism & Toxicology
Pharmacogenetics and Drug MetabolismSex and Gender in Healthcare
Cited by 199
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Ocular Drug Delivery to the Retina: Current Innovations and Future Perspectives
Kim, H. M., & Woo, S. J. (2021) · Pharmaceutics
Advanced Drug Delivery SystemsRetinal Diseases and Treatments
Cited by 198
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Genetics of P450 oxidoreductase: Sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations
Huang, N., Agrawal, V., Giacomini, K. M., & Miller, W. L. (2008) · Proceedings of the National Academy of Sciences
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 198
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Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on N-nitrosodiethylamine induced hepatocarcinogenesis
Jeena, K. J., Joy, K. L., & Kuttan, R. (1999) · Cancer Letters
Phytochemistry and Bioactivity StudiesCancer and biochemical research
Cited by 198
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Understanding the Critical Disposition Pathways of Statins to Assess Drug–Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1
Elsby, R., Hilgendorf, C., & Fenner, K. (2012) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 198
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Ca 2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen 1
Ray, S. D., Kamendulis, L. M., Gurule, M. W., Yorkin, R. D., & Corcoran, G. B. (1993) · The FASEB Journal
Drug-Induced Hepatotoxicity and ProtectionCell death mechanisms and regulation
Cited by 198
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How to Recognize and Workaround Pitfalls in QSAR Studies: A Critical Review
Scior, T., Medina-Franco, J. L., Do, Q.-T., Martinez-Mayorga, K., Yunes Rojas, J. A., & Bernard, P. (2009) · Current Medicinal Chemistry
Computational Drug Discovery MethodsAdvanced Chemical Physics Studies
Cited by 197
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Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics
Haiser, H. J., Seim, K. L., Balskus, E. P., & Turnbaugh, P. J. (2014) · Gut Microbes
Pharmacogenetics and Drug MetabolismGut microbiota and health
Cited by 197
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Hepatoprotective Effect of Myristicin from Nutmeg ( Myristica fragrans ) on Lipopolysaccharide/ d -Galactosamine-Induced Liver Injury
Morita, T., Jinno, K., Kawagishi, H., Arimoto, Y., Suganuma, H., Inakuma, T., & Sugiyama, K. (2003) · Journal of Agricultural and Food Chemistry
Drug-Induced Hepatotoxicity and ProtectionMedicinal Plant Research
Cited by 197
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c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice
Win, S., Than, T. A., Han, D., Petrovic, L. M., & Kaplowitz, N. (2011) · Journal of Biological Chemistry
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 197
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Niosomal drug delivery systems for ocular disease-recent advances and future prospects
Durak, S., Esmaeili Rad, M., Alp Yetisgin, A., Eda Sutova, H., Kutlu, O., Cetinel, S., & Zarrabi, A. (2020) · Nanomaterials
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 196
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A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research
Yadav, V., Krishnan, A., & Vohora, D. (2020) · Journal of Ethnopharmacology
Piperaceae Chemical and Biological StudiesMedicinal Plant Research
Cited by 196
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Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth
Yang, N., Gong, F., Liu, B., Hao, Y., Chao, Y., Lei, H., Yang, X., Gong, Y., Wang, X., Liu, Z., et al. (2022) · Nature Communications
Hydrogen's biological and therapeutic effectsHydrogen Storage and Materials
Cited by 196
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Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling
Wawer, M. J., Li, K., Gustafsdottir, S. M., Ljosa, V., Bodycombe, N. E., Marton, M. A., Sokolnicki, K. L., Bray, M.-A., Kemp, M. M., Winchester, E., et al. (2014) · Proceedings of the National Academy of Sciences
Computational Drug Discovery MethodsCell Image Analysis Techniques
Cited by 196
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Advances in ophthalmic drug delivery
Morrison, P. W., & Khutoryanskiy, V. V. (2014) · Therapeutic Delivery
Advanced Drug Delivery SystemsOcular Surface and Contact Lens
Cited by 196
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Statistical evaluation of the Predictive Toxicology Challenge 2000–2001
Toivonen, H., Srinivasan, A., King, R. D., Kramer, S., & Helma, C. (2003) · Bioinformatics
Computational Drug Discovery MethodsCarcinogens and Genotoxicity Assessment
Cited by 196
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Hyaluronic acid in ocular drug delivery
Zhang, X., Wei, D., Xu, Y., & Zhu, Q. (2021) · Carbohydrate Polymers
Advanced Drug Delivery SystemsHydrogels: synthesis, properties, applications
Cited by 196
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Ligand efficiency and fragment-based drug discovery
Bembenek, S. D., Tounge, B. A., & Reynolds, C. H. (2009) · Drug Discovery Today
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 196
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Unleashing the power of generative AI in drug discovery
Gangwal, A., & Lavecchia, A. (2024) · Drug Discovery Today
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 195
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Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care
DeGorter, M. K., Tirona, R. G., Schwarz, U. I., Choi, Y.-H., Dresser, G. K., Suskin, N., Myers, K., Zou, G., Iwuchukwu, O., Wei, W.-Q., et al. (2013) · Circulation: Cardiovascular Genetics
Pharmacogenetics and Drug MetabolismLipoproteins and Cardiovascular Health
Cited by 195
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