Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Multiple forms of human P450 expressed in Saccharomyces cerevisiae
Imaoka, S., Yamada, T., Hiroi, T., Hayashi, K., Sakaki, T., Yabusaki, Y., & Funae, Y. (1996) · Biochemical Pharmacology
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 207
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DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome
Luo, H., Chen, J., Shi, L., Mikailov, M., Zhu, H., Wang, K., He, L., & Yang, L. (2011) · Nucleic Acids Research
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 206
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A critical overview of computational approaches employed for COVID-19 drug discovery
Muratov, E. N., Amaro, R., Andrade, C. H., Brown, N., Ekins, S., Fourches, D., Isayev, O., Kozakov, D., Medina-Franco, J. L., Merz, K. M., et al. (2021) · Chemical Society Reviews
Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Cited by 206
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Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium
Lépine, J., Bernard, O., Plante, M., Têtu, B., Pelletier, G., Labrie, F., Bélanger, A., & Guillemette, C. (2004) · The Journal of Clinical Endocrinology & Metabolism
Pharmacogenetics and Drug MetabolismEstrogen and related hormone effects
Cited by 205
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Covalently Bound Lipids of Human Stratum Corneum
Wertz, P. W., Madison, K. C., & Downing, D. T. (1989) · Journal of Investigative Dermatology
Advancements in Transdermal Drug DeliveryDermatology and Skin Diseases
Cited by 205
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Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology
Romano, R. M., Romano, M. A., Bernardi, M. M., Furtado, P. V., & Oliveira, C. A. (2010) · Archives of Toxicology
Pesticide Exposure and ToxicityEffects and risks of endocrine disrupting chemicals
Cited by 204
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A REVIEW OF KETAMINE ABUSE AND DIVERSION: Review: Ketamine
Sassano-Higgins, S., Baron, D., Juarez, G., Esmaili, N., & Gold, M. (2016) · Depression and Anxiety
Forensic Toxicology and Drug AnalysisSubstance Abuse Treatment and Outcomes
Cited by 204
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The Solubility–Permeability Interplay: Mechanistic Modeling and Predictive Application of the Impact of Micellar Solubilization on Intestinal Permeation
Miller, J. M., Beig, A., Krieg, B. J., Carr, R. A., Borchardt, T. B., Amidon, G. E., Amidon, G. L., & Dahan, A. (2011) · Molecular Pharmaceutics
Drug Solubulity and Delivery SystemsSurfactants and Colloidal Systems
Cited by 204
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An Educational Intervention to Improve Physician Reporting of Adverse Drug Reactions: A Cluster-Randomized Controlled Trial
Figueiras, A., Herdeiro, M. T., Polónia, J., & Gestal-Otero, J. J. (2006) · JAMA
Pharmacovigilance and Adverse Drug ReactionsPharmaceutical industry and healthcare
Cited by 204
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A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports
Tatonetti, N. P., Fernald, G. H., & Altman, R. B. (2012) · Journal of the American Medical Informatics Association
Pharmacovigilance and Adverse Drug ReactionsPharmaceutical Practices and Patient Outcomes
Cited by 203
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A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices
van Midwoud, P. M., Merema, M. T., Verpoorte, E., & Groothuis, G. M. M. (2010) · Lab on a Chip
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 203
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PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral®
Italia, J. L., Bhatt, D. K., Bhardwaj, V., Tikoo, K., & Kumar, M. N. V. R. (2007) · Journal of Controlled Release
Advanced Drug Delivery SystemsDrug Solubulity and Delivery Systems
Cited by 203
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Quantifying drug combination synergy along potency and efficacy axes
Meyer, C. T., Wooten, D. J., Paudel, B. B., Bauer, J., Hardeman, K. N., Westover, D., Lovly, C. M., Harris, L. A., Tyson, D. R., & Quaranta, V. (2019) · Cell Systems
Computational Drug Discovery MethodsLung Cancer Treatments and Mutations
Cited by 202
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AI-Driven Drug Discovery: A Comprehensive Review
Ferreira, F. J. N., & Carneiro, A. S. (2025) · ACS Omega
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 202
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Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis
Prince, M. I., Burt, A. D., & Jones, D. E. J. (2002) · Gut
Drug-Induced Hepatotoxicity and ProtectionLiver Diseases and Immunity
Cited by 202
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Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system
Hansson, T., Tindberg, N., Ingelman-Sundberg, M., & Ko¨hler, C. (1990) · Neuroscience
Pharmacogenetics and Drug MetabolismAlcohol Consumption and Health Effects
Cited by 202
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A self-stabilized and water-responsive deliverable coenzyme-based polymer binary elastomer adhesive patch for treating oral ulcer
Cui, C., Mei, L., Wang, D., Jia, P., Zhou, Q., & Liu, W. (2023) · Nature Communications
Advanced Drug Delivery SystemsHydrogels: synthesis, properties, applications
Cited by 202
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Metabolism and disposition of dasatinib after oral administration to humans
Christopher, L. J., Cui, D., Wu, C., Luo, R., Manning, J. A., Bonacorsi, S. J., Lago, M., Allentoff, A., Lee, F. Y. F., McCann, B., et al. (2008) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismChronic Myeloid Leukemia Treatments
Cited by 202
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SAR Index: Quantifying the Nature of Structure−Activity Relationships
Peltason, L., & Bajorath, J. (2007) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds
Cited by 201
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Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell–Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury
Bell, C. C., Lauschke, V. M., Vorrink, S. U., Palmgren, H., Duffin, R., Andersson, T. B., & Ingelman-Sundberg, M. (2017) · Drug Metabolism and Disposition
Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives
Cited by 201
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Controlled release from bioerodible polymers: Effect of drug type and polymer composition
Frank, A., Rath, S. K., & Venkatraman, S. S. (2005) · Journal of Controlled Release
Advanced Drug Delivery Systemsbiodegradable polymer synthesis and properties
Cited by 201
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Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways
Li, M., Zhao, M., Fu, Y., Li, Y., Gong, T., Zhang, Z., & Sun, X. (2016) · Journal of Controlled Release
Advanced Drug Delivery SystemsRNA Interference and Gene Delivery
Cited by 201
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Steroid sulfotransferases
STROTT, C. A. (1996) · Endocrine Reviews
Pharmacogenetics and Drug MetabolismSteroid Chemistry and Biochemistry
Cited by 200
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Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales
Sistonen, J., Fuselli, S., Palo, J. U., Chauhan, N., Padh, H., & Sajantila, A. (2009) · Pharmacogenetics and Genomics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 200
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