Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Clinical pharmacokinetics of thalidomide
Teo, S. K., Colburn, W. A., Tracewell, W. G., Kook, K. A., Stirling, D. I., Jaworsky, M. S., Scheffler, M. A., Thomas, S. D., & Laskin, O. L. (2004) · Clinical Pharmacokinetics
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 150
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Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
Fischer, M., Coleman, R. G., Fraser, J. S., & Shoichet, B. K. (2014) · Nature Chemistry
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 149
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A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt.
Matsushita, N., Sogawa, K., Ema, M., Yoshida, A., & Fujii-Kuriyama, Y. (1993) · Journal of Biological Chemistry
Pharmacogenetics and Drug MetabolismToxic Organic Pollutants Impact
Cited by 149
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Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l -amino acid oxidase
Hiu, J. J., & Yap, M. K. K. (2020) · Biochemical Society Transactions
Venomous Animal Envenomation and StudiesHealthcare and Venom Research
Cited by 149
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Nitric oxide-releasing chitosan oligosaccharides as antibacterial agents
Lu, Y., Slomberg, D. L., & Schoenfisch, M. H. (2014) · Biomaterials
Advanced Drug Delivery SystemsAntimicrobial agents and applications
Cited by 149
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Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands
Bisson, W. H., Koch, D. C., O’Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., & Kolluri, S. K. (2009) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsToxic Organic Pollutants Impact
Cited by 149
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The IUPHAR/BPS guide to PHARMACOLOGY in 2022: curating pharmacology for COVID-19, malaria and antibacterials
Harding, S. D., Armstrong, J. F., Faccenda, E., Southan, C., Alexander, S. P. H., Davenport, A. P., Pawson, A. J., Spedding, M., Davies, J. A., & NC-IUPHAR (2022) · Nucleic Acids Research
Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Cited by 149
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Predicting the effect of cytochrome P450 inhibitors on substrate drugs: Analysis of physiologically based pharmacokinetic modeling submissions to the US Food and Drug Administration
Wagner, C., Pan, Y., Hsu, V., Grillo, J. A., Zhang, L., Reynolds, K. S., Sinha, V., & Zhao, P. (2015) · Clinical Pharmacokinetics
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 148
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Nose-to-brain delivery of insulin enhanced by a nanogel carrier
Picone, P., Sabatino, M. A., Ditta, L. A., Amato, A., San Biagio, P. L., Mulè, F., Giacomazza, D., Dispenza, C., & Di Carlo, M. (2018) · Journal of Controlled Release
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 148
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Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma: CYP3A4 induction by mitotane
Kroiss, M., Quinkler, M., Lutz, W. K., Allolio, B., & Fassnacht, M. (2011) · Clinical Endocrinology
Pharmacogenetics and Drug MetabolismAdrenal and Paraganglionic Tumors
Cited by 148
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2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions
Basse, M. J., Betzi, S., Bourgeas, R., Bouzidi, S., Chetrit, B., Hamon, V., Morelli, X., & Roche, P. (2012) · Nucleic Acids Research
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 148
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Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays
Shah, F., Leung, L., Barton, H. A., Will, Y., Rodrigues, A. D., Greene, N., & Aleo, M. D. (2015) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives
Cited by 148
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Enteric coating of oral solid dosage forms as a tool to improve drug bioavailability
Maderuelo, C., Lanao, J. M., & Zarzuelo, A. (2019) · European Journal of Pharmaceutical Sciences
Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems
Cited by 147
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Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex
Riad, A., Zeng, C., Weng, C.-C., Winters, H., Xu, K., Makvandi, M., Metz, T., Carlin, S., & Mach, R. H. (2018) · Scientific Reports
Pharmacological Receptor Mechanisms and EffectsCholesterol and Lipid Metabolism
Cited by 147
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Nanoparticles Coated with High Molecular Weight PEG Penetrate Mucus and Provide Uniform Vaginal and Colorectal Distribution in Vivo
Maisel, K., Reddy, M., Xu, Q., Chattopadhyay, S., Cone, R., Ensign, L. M., & Hanes, J. (2016) · Nanomedicine
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 147
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Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history
Sabbagh, A., Langaney, A., Darlu, P., Gérard, N., Krishnamoorthy, R., & Poloni, E. S. (2008) · BMC Genetics
Pharmacogenetics and Drug MetabolismForensic and Genetic Research
Cited by 147
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Cancer Risk Associated with Lorcaserin — The FDA’s Review of the CAMELLIA-TIMI 61 Trial
Sharretts, J., Galescu, O., Gomatam, S., Andraca-Carrera, E., Hampp, C., & Yanoff, L. (2020) · New England Journal of Medicine
Pharmacovigilance and Adverse Drug ReactionsPharmacology and Obesity Treatment
Cited by 147
- Verified
Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19
Wang, J., Liu, Z., Wang, W., Chen, X., Shu, Y., He, N., & Zhou, H. (2001) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 147
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Isotonitazene Quantitation and Metabolite Discovery in Authentic Forensic Casework
Krotulski, A. J., Papsun, D. M., Kacinko, S. L., & Logan, B. K. (2020) · Journal of Analytical Toxicology
Forensic Toxicology and Drug AnalysisOpioid Use Disorder Treatment
Cited by 146
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From “Special K” to “Special M”: The Evolution of the Recreational Use of Ketamine and Methoxetamine
Corazza, O., Assi, S., & Schifano, F. (2013) · CNS Neuroscience & Therapeutics
Forensic Toxicology and Drug AnalysisSubstance Abuse Treatment and Outcomes
Cited by 146
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Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components
Chatterjee, P., & Franklin, M. R. (2003) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismComplementary and Alternative Medicine Studies
Cited by 146
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PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2
McDonagh, E. M., Boukouvala, S., Aklillu, E., Hein, D. W., Altman, R. B., & Klein, T. E. (2014) · Pharmacogenetics and Genomics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 146
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Distribution of insulin in trigeminal nerve and brain after intranasal administration
Lochhead, J. J., Kellohen, K. L., Ronaldson, P. T., & Davis, T. P. (2019) · Scientific Reports
Advanced Drug Delivery SystemsBarrier Structure and Function Studies
Cited by 146
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New biomimetic barrier Permeapad™ for efficient investigation of passive permeability of drugs
di Cagno, M., Bibi, H. A., & Bauer-Brandl, A. (2015) · European Journal of Pharmaceutical Sciences
Drug Solubulity and Delivery SystemsAdvancements in Transdermal Drug Delivery
Cited by 146
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