Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro
Dash, A., Simmers, M. B., Deering, T. G., Berry, D. J., Feaver, R. E., Hastings, N. E., Pruett, T. L., LeCluyse, E. L., Blackman, B. R., & Wamhoff, B. R. (2013) · American Journal of Physiology-Cell Physiology
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 108
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Effect of mean diameter and polydispersity of PLG microspheres on drug release: Experiment and theory
Berchane, N. S., Carson, K. H., Rice-Ficht, A. C., & Andrews, M. J. (2007) · International Journal of Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 108
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Pharmacogenetic Randomized Trial for Cocaine Abuse: Disulfiram and Dopamine β-Hydroxylase
Kosten, T. R., Wu, G., Huang, W., Harding, M. J., Hamon, S. C., Lappalainen, J., & Nielsen, D. A. (2013) · Biological Psychiatry
Pharmacogenetics and Drug MetabolismNeurotransmitter Receptor Influence on Behavior
Cited by 108
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Systems pharmacology for drug discovery and development: paradigm shift or flash in the pan?
Vicini, P., & van der Graaf, P. H. (2013) · Clinical Pharmacology & Therapeutics
Computational Drug Discovery MethodsStatistical Methods in Clinical Trials
Cited by 108
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Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury
Schneider, K. M., Elfers, C., Ghallab, A., Schneider, C. V., Galvez, E. J. C., Mohs, A., Gui, W., Candels, L. S., Wirtz, T. H., Zuehlke, S., et al. (2021) · Cellular and Molecular Gastroenterology and Hepatology
Drug-Induced Hepatotoxicity and ProtectionGut microbiota and health
Cited by 108
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Alginic acid-coated chitosan nanoparticles loaded with legumain DNA vaccine: effect against breast cancer in mice
Liu, Z., Lv, D., Liu, S., Gong, J., Wang, D., Xiong, M., Chen, X., Xiang, R., & Tan, X. (2013) · PLoS ONE
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 108
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The operational multiple dosing half-life: a key to defining drug accumulation in patients and to designing extended release dosage forms
Sahin, S., & Benet, L. Z. (2008) · Pharmaceutical Research
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 108
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β-Glucuronidases of opportunistic bacteria are the major contributors to xenobiotic-induced toxicity in the gut
Dashnyam, P., Mudududdla, R., Hsieh, T.-J., Lin, T.-C., Lin, H.-Y., Chen, P.-Y., Hsu, C.-Y., & Lin, C.-H. (2018) · Scientific Reports
Pharmacogenetics and Drug MetabolismEnzyme Structure and Function
Cited by 108
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Nanomicellar topical aqueous drop formulation of rapamycin for back-of-the-eye delivery
Cholkar, K., Gunda, S., Earla, R., Pal, D., & Mitra, A. K. (2015) · AAPS PharmSciTech
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 108
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Statin myotoxicity: a review of genetic susceptibility factors
Needham, M., & Mastaglia, F. L. (2014) · Neuromuscular Disorders
Pharmacogenetics and Drug MetabolismLipoproteins and Cardiovascular Health
Cited by 108
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Impaired drug absorption due to high stomach pH: a review of strategies for mitigation of such effect to enable pharmaceutical product development
Mitra, A., & Kesisoglou, F. (2013) · Molecular Pharmaceutics
Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems
Cited by 108
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Anti-Inflammatory and Anticancer Drugs from Nature
Orlikova, B., Legrand, N., Panning, J., Dicato, M., & Diederich, M. (2014) · Cancer Treatment and Research
Bioactive natural compoundsMedicinal Plant Research
Cited by 108
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Network medicine framework for identifying drug-repurposing opportunities for COVID-19
Morselli Gysi, D., do Valle, Í., Zitnik, M., Ameli, A., Gan, X., Varol, O., Ghiassian, S. D., Patten, J. J., Davey, R. A., Loscalzo, J., et al. (2021) · Proceedings of the National Academy of Sciences
Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Cited by 107
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Purification, cDNA cloning, and tissue distribution of bovine liver aldehyde oxidase
Li-Calzi, M., Raviolo, C., Ghibaudi, E., De Gioia, L., Salmona, M., Cazzaniga, G., Kurosaki, M., Terao, M., & Garattini, E. (1995) · Journal of Biological Chemistry
Pharmacogenetics and Drug MetabolismEnzyme Structure and Function
Cited by 107
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Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design
Lv, H., Shi, L., Berkenpas, J. W., Dao, F.-Y., Zulfiqar, H., Ding, H., Zhang, Y., Yang, L., & Cao, R. (2021) · Briefings in Bioinformatics
Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Cited by 107
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The promise and pitfalls of intranasally administering psychopharmacological agents for the treatment of psychiatric disorders
Quintana, D. S., Guastella, A. J., Westlye, L. T., & Andreassen, O. A. (2016) · Molecular Psychiatry
Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery
Cited by 107
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An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery
Parrott, N., Paquereau, N., Coassolo, P., & Lavé, T. (2005) · Journal of Pharmaceutical Sciences
Computational Drug Discovery MethodsPharmacogenetics and Drug Metabolism
Cited by 107
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Membrane properties for permeability testing: Skin versus synthetic membranes
Haq, A., Dorrani, M., Goodyear, B., Joshi, V., & Michniak-Kohn, B. (2018) · International Journal of Pharmaceutics
Advancements in Transdermal Drug DeliveryAdvanced Drug Delivery Systems
Cited by 107
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Disproportionality Analysis From World Health Organization Data on Semaglutide, Liraglutide, and Suicidality
Schoretsanitis, G., Weiler, S., Barbui, C., Raschi, E., & Gastaldon, C. (2024) · JAMA Network Open
Pharmacovigilance and Adverse Drug ReactionsSuicide and Self-Harm Studies
Cited by 107
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A review of criteria strictness in “Toxicity Grading Scale for Healthy Adult and Adolescent Volunteers Enrolled in Preventive Vaccine Clinical Trials”
Amai, M., Nojima, M., Yuki, Y., Kiyono, H., & Nagamura, F. (2023) · Vaccine
Pharmacovigilance and Adverse Drug ReactionsStatistical Methods in Clinical Trials
Cited by 107
- Verified
Role of Oxidative Stress in Liver Disorders
Conde de la Rosa, L., Goicoechea, L., Torres, S., Garcia-Ruiz, C., & Fernandez-Checa, J. C. (2022) · Livers
Drug-Induced Hepatotoxicity and ProtectionAntioxidant Activity and Oxidative Stress
Cited by 107
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Predicting the accuracy of protein–ligand docking on homology models
Bordogna, A., Pandini, A., & Bonati, L. (2011) · Journal of Computational Chemistry
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 107
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The effects of age and glutathione depletion on hepatic glutathione turnover in vivo determined by acetaminophen probe analysis.
Lauterburg, B. H., Vaishnav, Y., Stillwell, W. G., & Mitchell, J. R. (1980) · The Journal of Pharmacology and Experimental Therapeutics
Drug-Induced Hepatotoxicity and ProtectionSulfur Compounds in Biology
Cited by 107
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Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders
Rassu, G., Porcu, E. P., Fancello, S., Obinu, A., Senes, N., Galleri, G., Migheli, R., Gavini, E., & Giunchedi, P. (2018) · Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 107
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