Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: A nationwide analysis†
Nguyen, G. C., Sam, J., & Thuluvath, P. J. (2008) · Hepatology
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 107
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Montelukast-loaded nanostructured lipid carriers: Part I Oral bioavailability improvement
Patil-Gadhe, A., & Pokharkar, V. (2014) · European Journal of Pharmaceutics and Biopharmaceutics
Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems
Cited by 107
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Biopharmaceutic classification system: a scientific framework for pharmacokinetic optimization in drug research
Varma, M., Khandavilli, S., Ashokraj, Y., Jain, A., Dhanikula, A., Sood, A., Thomas, N., Pillai, O., Sharma, P., Gandhi, R., et al. (2004) · Current Drug Metabolism
Drug Solubulity and Delivery SystemsComputational Drug Discovery Methods
Cited by 107
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Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery
Valkov, E., Sharpe, T., Marsh, M., Greive, S., & Hyvönen, M. (2011) · Topics in Current Chemistry
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 107
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Machine learning consensus scoring improves performance across targets in structure-based virtual screening.
Ericksen, S. S., Wu, H., Zhang, H., Michael, L. A., Newton, M. A., Hoffmann, F. M., & Wildman, S. A. (2017) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 107
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Computer especially AI-assisted drug virtual screening and design in traditional Chinese medicine
Lin, Y., Zhang, Y., Wang, D., Yang, B., & Shen, Y.-Q. (2022) · Phytomedicine
Computational Drug Discovery MethodsTraditional Chinese Medicine Analysis
Cited by 107
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Gender differences in pharmacokinetics and pharmacodynamics of zolpidem following sublingual administration
Greenblatt, D. J., Harmatz, J. S., Singh, N. N., Steinberg, F., Roth, T., Moline, M. L., Harris, S. C., & Kapil, R. P. (2014) · The Journal of Clinical Pharmacology
Pharmacogenetics and Drug MetabolismAnesthesia and Sedative Agents
Cited by 107
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Modeling the binding of diverse ligands within the Ah receptor ligand binding domain
Giani Tagliabue, S., Faber, S. C., Motta, S., Denison, M. S., & Bonati, L. (2019) · Scientific Reports
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 106
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Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells
Tanjoni, I., Weinlich, R., Della-Casa, M. S., Clissa, P. B., Saldanha-Gama, R. F., de Freitas, M. S., Barja-Fidalgo, C., Amarante-Mendes, G. P., & Moura-da-Silva, A. M. (2005) · Apoptosis
Venomous Animal Envenomation and StudiesCell death mechanisms and regulation
Cited by 106
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The Use of Human Hepatocytes to Select Compounds Based on Their Expected Hepatic Extraction Ratios in Humans
Lavé, T., Dupin, S., Schmitt, C., Valles, B., Ubeaud, G., Chou, R. C., Jaeck, D., & Coassolo, P. (1997) · Pharmaceutical Research
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 106
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Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
Reay, J. L., Scholey, A. B., & Kennedy, D. O. (2010) · Human Psychopharmacology Clinical and Experimental
Ginseng Biological Effects and ApplicationsMedicinal Plants and Bioactive Compounds
Cited by 106
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Comparison of LC-MS-MS and GC-MS Analysis of Benzodiazepine Compounds Included in the Drug Demand Reduction Urinalysis Program
Perez, E. R., Knapp, J. A., Horn, C. K., Stillman, S. L., Evans, J. E., & Arfsten, D. P. (2016) · Journal of Analytical Toxicology
Forensic Toxicology and Drug AnalysisAnalytical Methods in Pharmaceuticals
Cited by 106
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Implementation and utilization of genetic testing in personalized medicine
Scott, S., Abul-Husn, N., Owusu Obeng, A., Sanderson, S., & Gottesman, O. (2014) · Pharmacogenomics and Personalized Medicine
Pharmacogenetics and Drug MetabolismGenomics and Rare Diseases
Cited by 106
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Glyphosate: too much of a good thing?
Cuhra, M., Bøhn, T., & Cuhra, P. (2016) · Frontiers in Environmental Science
Pesticide Exposure and ToxicityPesticide and Herbicide Environmental Studies
Cited by 106
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The blood-brain barrier and nasal drug delivery to the central nervous system
Miyake, M. M., & Bleier, B. S. (2015) · American Journal of Rhinology & Allergy
Advanced Drug Delivery SystemsBarrier Structure and Function Studies
Cited by 106
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Hot-spot analysis for drug discovery targeting protein-protein interactions
Rosell, M., & Fernández-Recio, J. (2018) · Expert Opinion on Drug Discovery
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 105
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Rigidity Strengthening: A Mechanism for Protein–Ligand Binding
Nguyen, D. D., Xiao, T., Wang, M., & Wei, G.-W. (2017) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 105
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Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease
Theodoris, C. V., Zhou, P., Liu, L., Zhang, Y., Nishino, T., Huang, Y., Kostina, A., Ranade, S. S., Gifford, C. A., Uspenskiy, V., et al. (2021) · Science
Computational Drug Discovery MethodsGene Regulatory Network Analysis
Cited by 105
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Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase
Akakpo, J. Y., Ramachandran, A., Duan, L., Schaich, M. A., Jaeschke, M. W., Freudenthal, B. D., Ding, W.-X., Rumack, B. H., & Jaeschke, H. (2019) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 105
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Knowledge graphs and their applications in drug discovery
MacLean, F. (2021) · Expert Opinion on Drug Discovery
Computational Drug Discovery MethodsBiomedical Text Mining and Ontologies
Cited by 105
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Naphthoquinones: biological properties and synthesis of lawsone and derivates - a structured review
LÓPEZ LÓPEZ, L. I., NERY FLORES, S. D., SILVA BELMARES, S. Y., & SÁENZ GALINDO, A. (2014) · Vitae
Bioactive Compounds and Antitumor AgentsHeterocyclic Compound Synthesis and Bioactivity
Cited by 105
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Can paracetamol (acetaminophen) be administered to patients with liver impairment?
Hayward, K. L., Powell, E. E., Irvine, K. M., & Martin, J. H. (2016) · British Journal of Clinical Pharmacology
Drug-Induced Hepatotoxicity and ProtectionLiver Disease and Transplantation
Cited by 104
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Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men
Olubodun, J. O., Ochs, H. R., Von Moltke, L. L., Roubenoff, R., Hesse, L. M., Harmatz, J. S., Shader, R. I., & Greenblatt, D. J. (2003) · British Journal of Clinical Pharmacology
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 104
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Cisplatin-Induced Renal Toxicity via Tumor Necrosis Factor-α, Interleukin 6, Tumor Suppressor P53, DNA Damage, Xanthine Oxidase, Histological Changes, Oxidative Stress and Nitric Oxide in Rats: Protective Effect of Ginseng
Yousef, M. I., & Hussien, H. M. (2015) · Food and Chemical Toxicology
Chemotherapy-induced organ toxicity mitigationGinseng Biological Effects and Applications
Cited by 104
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