CoChat
Sign Up
Cited by 105Retinal Diseases and TreatmentsNutritional Studies and DietRetinal Imaging and Analysis

Relationship of dietary fat to age-related maculopathy in the Third National Health and Nutrition Examination Survey

Heuberger, Roschelle A.·2001·Archives of Ophthalmology
DOI 10.1001/archopht.119.12.1833
Open this paper in CoChat — free account

Abstract

OBJECTIVE: To evaluate the associations between dietary fat and age-related maculopathy (ARM) in persons 40 years or older who participated in the Third National Health and Nutrition Examination Survey. METHODS: We used a single, nonmydriatic, fundus photograph of 1 eye to ascertain ARM status in 7883 of 11 448 survey participants. Intake of fat was estimated from 24-hour recall, and specific sources of dietary fat were estimated from responses to food frequency questionnaires. Logistic regression was used to compute odds ratios (ORs) and 95% confidence intervals (CIs) that accounted for complex survey design, nonresponse, and potential risk factors for ARM (age, smoking, race, sex, body mass index, history of cardiovascular disease or hypertension, eye color, and sedentary lifestyle). Persons aged 40 to 79 years (n = 7405) were included in analyses for early ARM (n = 644); those 60 years or older (n = 4294) were included in analyses for late ARM (n = 53). RESULTS: After adjustment for age, race, eye color, and sedentary lifestyle, OR for early ARM was 1.4 (95% CI, 0.9-2.2; P for trend,.10) among persons in high vs low quintiles of total fat intake (percentage of total energy). Associations for specific types of fatty acids (as percentages of caloric intake) were in the same direction and unrelated to ARM. The OR for late ARM was 0.7 (95% CI, 0.2-2.6; P for trend,.60) in persons 60 years or older. Further adjustments for other potential confounders did not significantly affect the ORs. CONCLUSION: Age-related maculopathy was not significantly associated with dietary fat in this large cross-sectional survey.

Integrity signals

Registry

Crossref · 10.1001/archopht.119.12.1833

Cites

36 of 36 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Some evidence exists for a link between risk for age-related macular degeneration and increased levels of total dietary fat, although other studies have refuted this link.

    “Some evidence exists for a link between risk for age-related macular degeneration and increased levels of total dietary fat,84 although other studies have refuted this link.85”

    From Age-related macular degeneration (2008) · cites this paper as [85]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Heuberger, R. A.
Affiliations
University of Wisconsin–Madison (US)
Corresponding author
Heuberger, Roschelle A.
ORCID
Heuberger, Roschelle A.
Venue
Archives of Ophthalmology
Publisher
American Medical Association (AMA)
Published
2001-12-01
Volume
119
Issue
12
Pages
1833
ISSN
0003-9950 (ISSN-L)
DOI
10.1001/archopht.119.12.1833
OpenAlex
W2089158230
Cited by
105
References
36
Citations by year
2024: 1 · 2023: 1 · 2021: 3 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 6 · 2013: 4 · 2012: 10
FWCI
3.91
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Ophthalmology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01ey011722-03)
  • National Eye Institute (EY 11722)
Topics
  • Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Retinal Imaging and Analysis
Keywords
age-related maculopathy, dietary fat, total fat intake, fatty acids, macular degeneration, dietary risk factors, older adults
MeSH terms
Adult, Aged, Body Constitution, Cross-Sectional Studies, Dietary Fats, Eating, Eye Color, Feeding Behavior, Female, Humans, Life Style, Macular Degeneration, Male, Middle Aged, Nutrition Surveys, Risk Factors, United States

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review