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Cited by 187Inflammatory Bowel DiseaseMindfulness and Compassion InterventionsPsychosomatic Disorders and Their Treatments

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Psychological interventions for treatment of inflammatory bowel disease

Timmer, Antje, Preiss, Jan C, Motschall, Edith, Rücker, Gerta, Jantschek, Günther, Moser, Gabriele·2011·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd006913.pub2
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Abstract

BACKGROUND: The effect of psychological interventions in inflammatory bowel diseases (IBD) is controversial. OBJECTIVES: To assess the effects of psychological interventions (psychotherapy, patient education, relaxation techniques) on health related quality of life, coping, emotional state and disease activity in IBD. SEARCH STRATEGY: We searched the specialized register of the IBD/FBD Group, CENTRAL (Issue 5, 2010) and from inception to April 2010: Medline, Embase, LILACS, Psyndex, CINAHL, PsyInfo, CCMed, SOMED and Social SciSearch. Conference abstracts and reference lists were also checked. SELECTION CRITERIA: Randomized, quasi-randomized and non randomized controlled trials of psychological interventions in children or adults with IBD with a minimum follow up time of 2 months. DATA COLLECTION AND ANALYSIS: Data were extracted and study quality was independently assessed by two raters. Pooled standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated using a random effects model. MAIN RESULTS: Twenty-one studies were eligible for inclusion (1745 participants, 8 RCT, 4 QRCT, 8 NRCT; 19 in adults, 2 in adolescents). Most studies used multimodular approaches. The risk of bias was high for all studies.In adults, psychotherapy had no effect on quality of life at around 12 months (3 studies, 235 patients, SMD -0.07; 95% CI -0.33 to 0.19), emotional status (depression, 4 studies, 266 patients, SMD 0.03; 95% CI -0.22 to 0.27) or proportion of patients not in remission (5 studies, 287 patients, OR 0.85; 95% CI 0.48 to 1.48). Results were similar at 3 to 8 months. There was no evidence for statistical heterogeneity or subgroup effects based on type of disease or intensity of the therapy. In adolescents, there were positive short term effects of psychotherapy on most outcomes assessed including quality of life (2 studies, 71 patients, SMD 0.70; 95% CI 0.21 to 1.18) and depression (1 study, 41 patients, SMD -0.62; 95% CI -1.25 to 0.01).Educational interventions were ineffective with respect to quality of life at 12 months (5 studies, 947 patients, SMD 0.11; 95% CI -0.02 to 0.24), depression (3 studies, 378 patients, SMD -0.08; 95% CI -0.29 to 0.12) and proportion of patients not in remission (3 studies, 434 patients, OR 1.00; 95% CI 0.65 to 1.53). AUTHORS' CONCLUSIONS: There is no evidence for efficacy of psychological therapy in adult patients with IBD in general. In adolescents, psychological interventions may be beneficial, but the evidence is limited. Further evidence is needed to assess the efficacy of these therapies in subgroups identified as being in need of psychological interventions, and to identify what type of therapy maybe most useful.

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Research works printed but not linked: 27

  1. Balck, 2003, Evidence-based psychotherapy with chronic inflammatory bowel disease patients, Medizinische Welt, 54, 359
  2. Feiereis, 1995, Abschlussbericht des Projekts "Wirksamkeit psychotherapeutischer Massnahmen bei Morbus Crohn - eine multizentrische Studie"
  3. Wietersheim, 1999, [Effectiveness of psychotherapy as experienced by patients with Crohn's disease. Results of a multi center study], 1
  4. Kunsebeck, 1987, Short- and long-term effects of supplementary psychotherapy in patients with Crohn's disease, 253
  5. Haslbeck E Evaluation of the effectiveness of an patient education programme for IBD Thesis, University of Regensburg, Department of Clinical Psychology 1993 1 116
  6. Schmidt, 1992, Hypnotic suggestions and imaginations in the treatment of colitis ulcerosa, Hypnos, x, 237
  7. Schreiber, 1999, Efficacy of patient education in chronic inflammatory bowel disease in a prospective controlled multicenter trial (G 3535), Gastroenterology, 116, A 815
  8. Schwarz SP Treatment of inflammatory bowel disease: Comparing a multicomponent psychological treatment to a waiting-list control group Dissertation Abstracts International 1990 5919 20
  9. Misra, 2005, The Effect Of Education on Health Care Utilization in Patients with Inflammatory Bowel Disease, Gastroenterology, 128, A17
  10. Bruning DJ The effects of autogenic training on subjective stress levels, subjective symptoms and coping strategies in women with ulcerative colitis Dissertation Abstracts International 1991 4774
  11. Cabras, 1985, Applicazione del training autogeno alle psicosomatosi gastrointestinali, Medicina Psicosomatica, 30, 315
  12. Cabras Pier, 1986, Variazioni dell'immagine corporea nella pratica del training autogeno in pazienti con psicosomatosi gastrointestinali, Bollettino di Psicologia Applicata, 178, 27
  13. Diaz Sibaja, 2007, [Protocolized cognitive-behavioural group therapy for inflammatory bowel disease], Revista Espanola de Enfermedades Digestivas, 99, 593
  14. Gethins, 2009, Guided self management for patients with ulcerative colitis and Crohn's disease, Gut, 58, 153
  15. Hochgerner, 1998, Somato-psycho-soziale Therapie als integriertes Gesamtkonzept zur Behandlung psychosomatisch Erkrankter. Eine Untersuchung zum Erfolg stationaerer psychosomatischer Behandlung. Somatopsychosocial therapy as an integrated general concept for the treatment of psychosomatic patients: A study on psychosomatic inpatient treatment outcomes, Psychotherapie Forum, 6, 1
  16. Khorana, 1983, A study of psychological factors and psychotherapy on ulcerative colitis, Indian Journal of Clinical Psychology, 10, 459
  17. Robinson, 1999, Guided self-management in ulcerative colitis: Quicker treatment and more efficient use of health services [abstract], Gut, 44, A12
  18. Sachse, 2006, Psychologische Psychotherapie bei chronisch entzuendlichen Darmerkrankungen. Psychological psychotherapy of chronic inflammatory bowel diseases
  19. Sachse, 2007, Solution-oriented psychotherapy of chronic inflammatory bowel disease, 286
  20. Andrews, 2010, Does cognitive behavioural therapy (CBT) improve outcomes in IBD? Feasibility, patient acceptance and preliminary results, ECCO abstracts, P, 156
  21. Boye, 2008, The INSPIRE Study: Are different personality traits related to disease specific quality of life in distressed patients with ulcerative colitis and Crohn's disease?, Inflammatory Bowel Diseases, 14, 686
  22. Boye B Lundin KE Leganger S Mokleby K Tangen T Jantschek I Pripp AH Wojniusz S Dahlstrom A Rivelsrud AC Benninghoven D Jantschek G Hausken T Rodseth A Kunzendorf S Wilhelmsen I Sharpe M Blomhoff S Malt UF Jahnsen J The INSPIRE study: Does stress management intervention improve the course of IBD and diseases specific quality of life in distressed patients with ulcerative colitis and Crohn's disease? A randomized controlled intervention study manuscript under review
  23. Sharpe, 2008, The INSPIRE study: do personality traits predict general quality of life (SF 36) in distressed pateints with ulcerative colitis and Crohn's disease?, Scand J Gastroenterol, 43, 15051513
  24. Elsenbruch, 2005, Effects of mind-body therapy on quality of life and neuroendocrine and cellular immune functions in patients with ulcerative colitis, Psychotherapy & Psychosomatics, 74, 277, 10.1159/000086318 · DOI
  25. Kovacs, 1992, Children's Depression Inventory (CDI) Manual
  26. Richardson, 2006, Is self-care a cost-effective use of resources? Evidence from a randomized trial in inflammatory bowel disease, Journal of Health Services & Research Policy, 11, 225, 10.1258/135581906778476508 · DOI
  27. Verma, 2001, Does better disease-related education improve quality of life? A survey of IBD patients, Dig Dis Sci, 46, 865, 10.1023/A:1010725106411 · DOI

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Metadata

Authors
Timmer, A., Preiss, J. C., Motschall, E., Rücker, G., Jantschek, G., & Moser, G.
Affiliations
  • Leibniz Institute for Prevention Research and Epidemiology - BIPS (DE)
  • Charité – Universitätsmedizin Berlin (DE)
  • University Medical Center Freiburg (DE)
  • University Hospital Schleswig-Holstein (DE)
  • Medical University of Vienna (AT)
ORCID
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
2011-02-15
Issue
2
Pages
CD006913-CD006913
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
DOI
10.1002/14651858.cd006913.pub2
OpenAlex
W1830145075
Cited by
187
References
133
Citations by year
2026: 1 · 2025: 7 · 2024: 7 · 2023: 12 · 2022: 11 · 2021: 18 · 2020: 8 · 2019: 10 · 2018: 9 · 2017: 18 · 2016: 14 · 2015: 22 · 2014: 17 · 2013: 14 · 2012: 13
FWCI
1.65
Type
journal article
Language
en
Update notices
new_version (2025-04-17)
Open access
closed
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
inflammatory bowel disease, psychological intervention, psychotherapy, patient education, relaxation techniques, health-related quality of life, coping, depression, disease activity, remission, adolescents, children, risk of bias, attrition bias, publication bias
MeSH terms
Adolescent, Adult, Colitis, Ulcerative, Crohn Disease, Depression, Humans, Patient Education as Topic, Psychotherapy, Quality of Life, Inflammatory Bowel Diseases, Randomized Controlled Trials as Topic

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