The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Multifunctional Nanobiomaterials for Neural Interfaces
Open accessAbstract
Neural electrodes are designed to interface with the nervous system and provide control signals for neural prostheses. However, robust and reliable chronic recording and stimulation remains a challenge for neural electrodes. Here, a novel method for the fabrication of soft, low impedance, high charge density, and controlled releasing nanobiomaterials that can be used for the surface modification of neural microelectrodes to stabilize the electrode/tissue interface is reported. The fabrication process includes electrospinning of anti‐inflammatory drug‐incorporated biodegradable nanofibers, encapsulation of these nanofibers by an alginate hydrogel layer, followed by electrochemical polymerization of conducting polymers around the electrospun drug‐loaded nanofibers to form nanotubes and within the alginate hydrogel scaffold to form cloud‐like nanostructures. The three‐dimensional conducting polymer nanostructures significantly decrease the electrode impedance and increase the charge capacity density. Dexamethasone release profiles show that the alginate hydrogel coating slows down the release of the drug, significantly reducing the burst effect. These multifunctional materials are expected to be of interest for a variety of electrode/tissue interfaces in biomedical devices.
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Cites
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Chronic, multisite, multielectrode recordings in macaque monkeys
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Cited by
Yuk, H., Lu, B., & Zhao, X. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00595h · Cited by 2,108
Liu, X., Liu, J., Lin, S., & Zhao, X. (2020) · Materials Today · doi:10.1016/j.mattod.2019.12.026 · Cited by 1,023
Cai, G., Wang, J., Qian, K., Chen, J., Li, S., & Lee, P. S. (2017) · Advanced Science · doi:10.1002/advs.201600190 · Cited by 921
Soft and elastic hydrogel-based microelectronics for localized low-voltage neuromodulation
Liu, Y., Liu, J., Chen, S., Lei, T., Kim, Y., Niu, S., Wang, H., Wang, X., Foudeh, A. M., Tok, J. B.-H., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0335-6 · Cited by 811
Glial responses to implanted electrodes in the brain
Salatino, J. W., Ludwig, K. A., Kozai, T. D. Y., & Purcell, E. K. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0154-1 · Cited by 642
Metadata
- Authors
- Abidian, M. R., & Martin, D. C.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2009-02-19
- Volume
- 19
- Issue
- 4
- Pages
- 573-585
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2119989931
- Cited by
- 416
- References
- 13
- FWCI
- 10.66
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.