Recent advances in stimuli‐responsive theranostic systems with aggregation‐induced emission characteristics

Free radicals and antioxidants in normal physiological functions and human disease

Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., & Telser, J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.001 · Cited by 14,269 · see citing works

Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole

Luo, J., Xie, Z., Lam, J. W. Y., Cheng, L., Tang, B. Z., Chen, H., Qiu, C., Kwok, H. S., Zhan, X., Liu, Y., et al. (2001) · Chemical Communications · doi:10.1039/b105159h · Cited by 8,358 · see citing works

Aggregation-Induced Emission: Together We Shine, United We Soar!

Mei, J., Leung, N. L. C., Kwok, R. T. K., Lam, J. W. Y., & Tang, B. Z. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00263 · Cited by 8,270 · see citing works

Aggregation-induced emission

Hong, Y., Lam, J. W. Y., & Tang, B. Z. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15113d · Cited by 6,363 · see citing works

Stimuli-responsive nanocarriers for drug delivery

Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289 · see citing works

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2803 · Cited by 5,452 · see citing works

Doxil® — The first FDA-approved nano-drug: Lessons learned

Barenholz, Y. (. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.020 · Cited by 4,792 · see citing works

Modulation of oxidative stress as an anticancer strategy

Gorrini, C., Harris, I. S., & Mak, T. W. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4002 · Cited by 3,579 · see citing works

Structure and function of matrix metalloproteinases and TIMPs

Nagase, H., Visse, R., & MURPHY, G. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.12.002 · Cited by 3,416 · see citing works

Aggregation‐Induced Emission: The Whole Is More Brilliant than the Parts

Mei, J., Hong, Y., Lam, J. W. Y., Qin, A., Tang, Y., & Tang, B. Z. (2014) · Advanced Materials · doi:10.1002/adma.201401356 · Cited by 3,385 · see citing works

Near-infrared fluorophores for biomedical imaging

Hong, G., Antaris, A. L., & Dai, H. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0010 · Cited by 3,013 · see citing works

Mechanisms in photodynamic therapy: part one—photosensitizers, photochemistry and cellular localization

Castaño, A. P., Demidova, T. N., & Hamblin, M. R. (2004) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(05)00007-4 · Cited by 2,059 · see citing works

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

Ethirajan, M., Chen, Y., Joshi, P., & Pandey, R. K. (2010) · Chemical Society Reviews · doi:10.1039/b915149b · Cited by 2,038 · see citing works

Bioprobes Based on AIE Fluorogens

Ding, D., Li, K., Liu, B., & Tang, B. Z. (2013) · Accounts of Chemical Research · doi:10.1021/ar3003464 · Cited by 1,821 · see citing works

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

Torchilin, V. P. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4333 · Cited by 1,674 · see citing works

Nano-graphene in biomedicine: theranostic applications

Yang, K., Feng, L., Shi, X., & Liu, Z. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35342c · Cited by 1,638 · see citing works

The role of apoptosis in response to photodynamic therapy: what, where, why, and how

Oleinick, N. L., Morris, R. L., & Belitchenko, I. (2002) · Photochemical & Photobiological Sciences · doi:10.1039/b108586g · Cited by 1,502 · see citing works

Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery

Cheng, R., Feng, F., Meng, F., Deng, C., Feijén, J., & Zhong, Z. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.01.030 · Cited by 1,367 · see citing works

Biosensing by luminogens with aggregation-induced emission characteristics

Kwok, R. T. K., Leung, C. W. T., Lam, J. W. Y., & Tang, B. Z. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00325j · Cited by 1,298 · see citing works

multifunctional enzymes in cancer

Mohamed, M. M., & Sloane, B. F. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1949 · Cited by 1,267 · see citing works

Black Phosphorus Nanosheet‐Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

Chen, W., Ouyang, J., Liu, H., et al. (2016) · Advanced Materials · doi:10.1002/adma.201603864 · Cited by 1,027 · see citing works

Polymer-encapsulated organic nanoparticles for fluorescence and photoacoustic imaging

Li, K., & Liu, B. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00014e · Cited by 989 · see citing works

Changing the Behavior of Chromophores from Aggregation‐Caused Quenching to Aggregation‐Induced Emission: Development of Highly Efficient Light Emitters in the Solid State

Yuan, W. Z., Lü, P., Chen, S., Lam, J. W. Y., Wang, Z., Liu, Y., Kwok, H. S., Ma, Y., & Tang, B. Z. (2010) · Advanced Materials · doi:10.1002/adma.200904056 · Cited by 972 · see citing works

Theranostic Nanoshells: From Probe Design to Imaging and Treatment of Cancer

Bardhan, R., Lal, S., Joshi, A., & Halas, N. J. (2011) · Accounts of Chemical Research · doi:10.1021/ar200023x · Cited by 918 · see citing works

Theranostic Nanomedicine

Lammers, T., Aime, S., Hennink, W. E., Storm, G., & Kiessling, F. M. (2011) · Accounts of Chemical Research · doi:10.1021/ar200019c · Cited by 873 · see citing works

Photosensitizers with Aggregation‐Induced Emission: Materials and Biomedical Applications

Hu, F., Xu, S., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201801350 · Cited by 859 · see citing works

Mechanisms in photodynamic therapy: part two—cellular signaling, cell metabolism and modes of cell death

Castaño, A. P., Demidova, T. N., & Hamblin, M. R. (2005) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/s1572-1000(05)00030-x · Cited by 769 · see citing works

Specific light-up bioprobes based on AIEgen conjugates

Liang, J., Tang, B. Z., & Liu, B. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00444b · Cited by 762 · see citing works

Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response

Olson, O. C., & Joyce, J. A. (2015) · Nature reviews. Cancer · doi:10.1038/nrc4027 · Cited by 703 · see citing works

AIE Luminogens for Bioimaging and Theranostics: From Organelles to Animals

Qian, J., & Tang, B. Z. (2017) · Chem · doi:10.1016/j.chempr.2017.05.010 · Cited by 576 · see citing works

Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging

Ding, F., Zhan, Y., Lu, X., & Sun, Y. (2018) · Chemical Science · doi:10.1039/c8sc01153b · Cited by 540 · see citing works

Specific Light‐Up Bioprobe with Aggregation‐Induced Emission and Activatable Photoactivity for the Targeted and Image‐Guided Photodynamic Ablation of Cancer Cells

Yuan, Y., Zhang, C., Gao, M., Zhang, R., Tang, B. Z., & Liu, B. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201408476 · Cited by 523 · see citing works

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure

Chen, C., Ni, X., Jia, S., Liang, Y., Wu, X., Kong, D., & Ding, D. (2019) · Advanced Materials · doi:10.1002/adma.201904914 · Cited by 503 · see citing works

Near-Infrared Afterglow Luminescent Aggregation-Induced Emission Dots with Ultrahigh Tumor-to-Liver Signal Ratio for Promoted Image-Guided Cancer Surgery

Ni, X., Zhang, X., Duan, X., Zheng, H., Xue, X., & Ding, D. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b03936 · Cited by 483 · see citing works

Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

Yuan, Y., Kwok, R. T. K., Tang, B. Z., & Liu, B. (2014) · Journal of the American Chemical Society · doi:10.1021/ja411811w · Cited by 474 · see citing works

Stimuli-responsive nanomaterials for therapeutic protein delivery

Lu, Y., Sun, W., & Gu, Z. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.08.015 · Cited by 415 · see citing works

Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery

Koo, A. N., Lee, H. J., Kim, S. E., Chang, J. H., Park, C., Kim, C., Park, J. H., & Lee, S. C. (2008) · Chemical Communications · doi:10.1039/b815918a · Cited by 395 · see citing works

Blood-vessel closure using photosensitizers engineered for two-photon excitation

Collins, H. A., Khurana, M., Moriyama, E. H., Mariampillai, A. L. D., Dahlstedt, E., Baláž, M., Kuimova, M. K., Drobizhev, M. A., Yang, V. X. D., Phillips, D. R., et al. (2008) · Nature Photonics · doi:10.1038/nphoton.2008.100 · Cited by 395 · see citing works

Stimuli-responsive nanoparticles for targeting the tumor microenvironment

Du, J., Lane, L. A., & Nie, S. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.08.050 · Cited by 385 · see citing works

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

Kumar, R., Shin, W. S., Sunwoo, K., Kim, W. Y., Koo, S., Bhuniya, S., & Kim, J. S. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00224a · Cited by 381 · see citing works

Targeted photodynamic therapy via receptor mediated delivery systems

Sharman, W. M. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.08.015 · Cited by 373 · see citing works

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance

Wei, T., Chen, C., Liu, J., Liu, C., Posocco, P., Liu, X., Cheng, Q., Huo, S., Liang, Z., Fermeglia, M., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1418494112 · Cited by 371 · see citing works

Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

Hadler‐Olsen, E., Winberg, J., & Uhlin‐Hansen, L. (2013) · Tumor Biology · doi:10.1007/s13277-013-0842-8 · Cited by 367 · see citing works

Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

Qi, J., Chen, C., Zhang, X., Hu, X., Ji, S., Kwok, R. T. K., Lam, J. W. Y., Ding, D., & Tang, B. Z. (2018) · Nature Communications · doi:10.1038/s41467-018-04222-8 · Cited by 350 · see citing works

Regulating the Photophysical Property of Organic/Polymer Optical Agents for Promoted Cancer Phototheranostics

Chen, C., Ou, H., Liu, R., & Ding, D. (2019) · Advanced Materials · doi:10.1002/adma.201806331 · Cited by 344 · see citing works

Aggregation-induced emission: a coming-of-age ceremony at the age of eighteen

Yang, J., Chi, Z., Zhu, W., Tang, B. Z., & Li, Z. (2019) · Science China Chemistry · doi:10.1007/s11426-019-9512-x · Cited by 324 · see citing works

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

Lee, M. H., Sharma, A. K., Chang, M. J., Lee, J., Son, S., Sessler, J. L., Kang, C., & Kim, J. S. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00557a · Cited by 318 · see citing works

Chemiluminescence-Guided Cancer Therapy Using a Chemiexcited Photosensitizer

Mao, D., Wu, W., Ji, S., Chen, C., Hu, F., Kong, D., Ding, D., & Liu, B. (2017) · Chem · doi:10.1016/j.chempr.2017.10.002 · Cited by 317 · see citing works

Hydrogen Peroxide Inducible DNA Cross-Linking Agents: Targeted Anticancer Prodrugs

Kuang, Y., Balakrishnan, K., Gandhi, V. V., & Peng, X. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2073824 · Cited by 311 · see citing works

Synthetic materials at the forefront of gene delivery

Lostalé‐Seijo, I., & Montenegro, J. (2018) · Nature Reviews Chemistry · doi:10.1038/s41570-018-0039-1 · Cited by 310 · see citing works

Conjugated‐Polyelectrolyte‐Based Polyprodrug: Targeted and Image‐Guided Photodynamic and Chemotherapy with On‐Demand Drug Release upon Irradiation with a Single Light Source

Yuan, Y., Liu, J., & Liu, B. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201402189 · Cited by 303 · see citing works

Targeted Bioimaging and Photodynamic Therapy of Cancer Cells with an Activatable Red Fluorescent Bioprobe

Hu, F., Huang, Y., Zhang, G., Zhao, R., Yang, H., & Zhang, D. (2014) · Analytical Chemistry · doi:10.1021/ac502103t · Cited by 284 · see citing works

Calixarene‐Based Supramolecular AIE Dots with Highly Inhibited Nonradiative Decay and Intersystem Crossing for Ultrasensitive Fluorescence Image‐Guided Cancer Surgery

Chen, C., Ni, X., Tian, H., Liu, Q., Guo, D., & Ding, D. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201916430 · Cited by 280 · see citing works

pH-Responsive Capsules Engineered from Metal-Phenolic Networks for Anticancer Drug Delivery

Yuan, P., Guo, J., Ejima, H., Chen, X., Richardson, J. J., Sun, H., & Caruso, F. (2015) · Small · doi:10.1002/smll.201403343 · Cited by 269 · see citing works

A Photoactivatable AIE Polymer for Light‐Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking

Yuan, Y., Zhang, C., & Liu, B. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201503640 · Cited by 265 · see citing works

A Preloaded Amorphous Calcium Carbonate/Doxorubicin@Silica Nanoreactor for pH‐Responsive Delivery of an Anticancer Drug

Zhao, Y., Luo, Z. Y., Li, M., Qu, Q., Ma, X., Yu, S., & Zhao, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201408510 · Cited by 264 · see citing works

Ultra‐pH‐Responsive and Tumor‐Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti‐Cancer Efficacy

Xu, X., Wu, J., Liu, Y., Yu, M., Zhao, L., Zhu, X., Bhasin, S., Li, Q., Ha, E., Shi, J., et al. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201601273 · Cited by 252 · see citing works

An Intracellular H2O2‐Responsive AIEgen for the Peroxidase‐Mediated Selective Imaging and Inhibition of Inflammatory Cells

Cheng, Y., Dai, J., Sun, C., Liu, R., Zhai, T., Lou, X., & Xia, F. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201712803 · Cited by 241 · see citing works

Aggregation-Induced Emission Photosensitizers: From Molecular Design to Photodynamic Therapy

Dai, J., Wu, X., Ding, S., Lou, X., Xia, F., Wang, S., & Hong, Y. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b02014 · Cited by 238 · see citing works

Physical, Chemical, and Biological Structures based on ROS‐Sensitive Moieties that are Able to Respond to Oxidative Microenvironments

Tapeinos, C., & Pandit, A. S. (2016) · Advanced Materials · doi:10.1002/adma.201505376 · Cited by 237 · see citing works

pH-Responsive Poly(<scp>d</scp>,<scp>l</scp>-lactic-<i>co</i>-glycolic acid) Nanoparticles with Rapid Antigen Release Behavior Promote Immune Response

Liu, Q., Chen, X., Jia, J., Zhang, W., Yang, T., Wang, L., & Ma, G. (2015) · ACS Nano · doi:10.1021/nn5066793 · Cited by 233 · see citing works

Dual Intratumoral Redox/Enzyme-Responsive NO-Releasing Nanomedicine for the Specific, High-Efficacy, and Low-Toxic Cancer Therapy

Jia, X., Zhang, Y., Zou, Y., Wang, Y., Niu, D., He, Q., Huang, Z., Zhu, W., Tian, H., Shi, J., et al. (2018) · Advanced Materials · doi:10.1002/adma.201704490 · Cited by 232 · see citing works

Recent advances in photonanomedicines for enhanced cancer photodynamic therapy

Hu, J., Lei, Q., & Zhang, X. (2020) · Progress in Materials Science · doi:10.1016/j.pmatsci.2020.100685 · Cited by 228 · see citing works

Efficient Near-Infrared Photosensitizer with Aggregation-Induced Emission for Imaging-Guided Photodynamic Therapy in Multiple Xenograft Tumor Models

Dai, J., Li, Y., Long, Z., Jiang, R., Zhuang, Z., Wang, Z., Zhao, Z., Lou, X., Xia, F., & Tang, B. Z. (2019) · ACS Nano · doi:10.1021/acsnano.9b07972 · Cited by 215 · see citing works

Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation‐Induced Emission

Xue, X., Zhao, Y., Dai, L., Zhang, X., Hao, X., Zhang, C., Huo, S., Liu, J., Liu, C., Kumar, A., et al. (2014) · Advanced Materials · doi:10.1002/adma.201302365 · Cited by 206 · see citing works

Targeted and image-guided photodynamic cancer therapy based on organic nanoparticles with aggregation-induced emission characteristics

Yuan, Y., Feng, G., Qin, W., Tang, B. Z., & Liu, B. (2014) · Chemical Communications · doi:10.1039/c4cc02767a · Cited by 205 · see citing works

A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells

Yuan, Y., Zhang, C., Xu, S., & Liu, B. (2015) · Chemical Science · doi:10.1039/c5sc03583j · Cited by 205 · see citing works

Hybrid Nanospheres to Overcome Hypoxia and Intrinsic Oxidative Resistance for Enhanced Photodynamic Therapy

Shi, L., Hu, F., Duan, Y., Wu, W., Dong, J., Meng, X., Zhu, X., & Liu, B. (2020) · ACS Nano · doi:10.1021/acsnano.9b09032 · Cited by 203 · see citing works

A Preloaded Amorphous Calcium Carbonate/Doxorubicin@Silica Nanoreactor for pH‐Responsive Delivery of an Anticancer Drug

Zhao, Y., Luo, Z. Y., Li, M., Qu, Q., Ma, X., Yu, S., & Zhao, Y. (2014) · Angewandte Chemie · doi:10.1002/ange.201408510 · Cited by 174 · see citing works

Light‐Up Probe for Targeted and Activatable Photodynamic Therapy with Real‐Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses

Yuan, Y., Zhang, C., Kwok, R. T. K., Xu, S., Zhang, R., Wu, J., Tang, B. Z., & Liu, B. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201502728 · Cited by 167 · see citing works

Light‐Responsive, Singlet‐Oxygen‐Triggered On‐Demand Drug Release from Photosensitizer‐Doped Mesoporous Silica Nanorods for Cancer Combination Therapy

Yang, G., Sun, X., Liu, J., Feng, L., & Liu, Z. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201600722 · Cited by 162 · see citing works

Modular Design of Peptide- or DNA-Modified AIEgen Probes for Biosensing Applications

Xia, F., Wu, J., Wu, X., Hu, Q., Dai, J., & Lou, X. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00348 · Cited by 155 · see citing works

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

Li, Z., Hu, J., Xu, Q., Chen, S., Jia, H.-Z., Sun, Y., Zhuo, R., & Zhang, X. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb01533a · Cited by 149 · see citing works

Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy

Chen, X., Gao, H., Deng, Y., Jin, Q., Ji, J., & Ding, D. (2020) · ACS Nano · doi:10.1021/acsnano.0c02197 · Cited by 142 · see citing works

An AIEgen‐Peptide Conjugate as a Phototheranostic Agent for Phagosome‐Entrapped Bacteria

Qi, G., Hu, F., Kenry, K., Shi, L., Wu, M., & Liu, B. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201906099 · Cited by 135 · see citing works

Drug delivery micelles with efficient near-infrared photosensitizer for combined image-guided photodynamic therapy and chemotherapy of drug-resistant cancer

Zhen, S., Yi, X., Zhao, Z., Lou, X., Xia, F., & Tang, B. Z. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119330 · Cited by 134 · see citing works

Advances in Peptide Functionalization on Mesoporous Silica Nanoparticles for Controlled Drug Release

Hu, J., Dong, X., & Zhang, X. (2016) · Small · doi:10.1002/smll.201600325 · Cited by 130 · see citing works

Light‐Induced Self‐Escape of Spherical Nucleic Acid from Endo/Lysosome for Efficient Non‐Cationic Gene Delivery

Shi, L., Wu, W., Duan, Y., Xu, L., Xu, Y., Hou, L., Meng, X., Zhu, X., & Liu, B. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202006890 · Cited by 127 · see citing works

Silicon‐Nanowire‐Based Nanocarriers with Ultrahigh Drug‐Loading Capacity for In Vitro and In Vivo Cancer Therapy

Peng, F., Su, Y., Wei, X., et al. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201206737 · Cited by 126 · see citing works

A positive feedback strategy for enhanced chemotherapy based on ROS-triggered self-accelerating drug release nanosystem

Hu, J., Lei, Q., Peng, M., et al. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.03.010 · Cited by 124 · see citing works

A theranostic prodrug delivery system based on Pt(IV) conjugated nano-graphene oxide with synergistic effect to enhance the therapeutic efficacy of Pt drug

Li, J., Lyv, Z., Li, Y., Liu, H., Wang, J., Zhan, W., Chen, H., Chen, H., & Li, X. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.01.074 · Cited by 123 · see citing works

pH-Sensitive siRNA Nanovector for Targeted Gene Silencing and Cytotoxic Effect in Cancer Cells

Mok, H., Veiseh, O., Chen, F., et al. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100221h · Cited by 123 · see citing works

Zwitterionic Phosphorylcholine–TPE Conjugate for pH-Responsive Drug Delivery and AIE Active Imaging

Chen, Y., Han, H., Tong, H., Chen, T., Wang, H., Ji, J., & Jin, Q. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b06071 · Cited by 121 · see citing works

Fabrication of pH-Responsive Nanoparticles with an AIE Feature for Imaging Intracellular Drug Delivery

Wang, X., Yang, Y., Zhuang, Y., Gao, P., Yang, F., Shen, H. Y., Guo, H., & Wu, D. (2016) · Biomacromolecules · doi:10.1021/acs.biomac.6b00744 · Cited by 120 · see citing works

Fluorescence techniques for drug delivery research: theory and practice

White, N. S. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.08.003 · Cited by 112 · see citing works

Cellular Uptake and Cytotoxicity of Drug–Peptide Conjugates Regulated by Conjugation Site

Zhang, P., Cheetham, A. G., Lock, L. L., et al. (2013) · Bioconjugate Chemistry · doi:10.1021/bc300585h · Cited by 107 · see citing works

AIE based GSH activatable photosensitizer for imaging-guided photodynamic therapy

Zhang, Y.-H., Li, X., Li, H., Kim, H. S., An, J., Lan, M., Cao, Q., & Kim, J. S. (2020) · Chemical Communications · doi:10.1039/d0cc02045a · Cited by 103 · see citing works

Probe-Inspired Nano-Prodrug with Dual-Color Fluorogenic Property Reveals Spatiotemporal Drug Release in Living Cells

Xue, X., Jin, S., Zhang, C., Yang, K., Huo, S., Chen, F., Zou, G., & Liang, X. (2015) · ACS Nano · doi:10.1021/nn5065452 · Cited by 98 · see citing works

A targeted theranostic platinum(iv) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation

Yuan, Y., Chen, Y., Tang, B. Z., & Liu, B. (2014) · Chemical Communications · doi:10.1039/c3cc49516g · Cited by 97 · see citing works

A high therapeutic efficacy of polymeric prodrug nano-assembly for a combination of photodynamic therapy and chemotherapy

Yi, X., Dai, J., Han, Y., Xu, M., Zhang, X., Zhen, S., Zhao, Z., Lou, X., & Xia, F. (2018) · Communications Biology · doi:10.1038/s42003-018-0204-6 · Cited by 96 · see citing works

Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy

Jin, G., Feng, G., Qin, W., Tang, B. Z., Liu, B., & Li, K. (2016) · Chemical Communications · doi:10.1039/c5cc07818k · Cited by 95 · see citing works

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems

Jones, A. T., Gumbleton, M., & Duncan, R. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.07.002 · Cited by 94 · see citing works

Protease-Responsive Prodrug with Aggregation-Induced Emission Probe for Controlled Drug Delivery and Drug Release Tracking in Living Cells

Cheng, Y., Huang, F., Min, X., Gao, P., Zhang, T., Li, X., Liu, B., Hong, Y., Lou, X., & Xia, F. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b02833 · Cited by 94 · see citing works

Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy

Hu, F., Yuan, Y., Mao, D., Wu, W., & Liu, B. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.08.018 · Cited by 92 · see citing works

A pH-responsive drug delivery system with an aggregation-induced emission feature for cell imaging and intracellular drug delivery

Wang, H., Liu, G., Gao, H., & Wang, Y. (2015) · Polymer Chemistry · doi:10.1039/c5py00584a · Cited by 91 · see citing works

Targeted theranostic prodrugs based on an aggregation-induced emission (AIE) luminogen for real-time dual-drug tracking

Yuan, Y., Kwok, R. T. K., Zhang, R., Tang, B. Z., & Liu, B. (2014) · Chemical Communications · doi:10.1039/c4cc05255b · Cited by 91 · see citing works

Visualization of drug delivery processes using AIEgens

Yuan, Y., & Liu, B. (2017) · Chemical Science · doi:10.1039/c6sc05421h · Cited by 90 · see citing works

A Transformable Chimeric Peptide for Cell Encapsulation to Overcome Multidrug Resistance

Zhang, C., Liu, L., Qiu, W., Zhang, Y., Song, W. L., Zhang, L., Wang, S., & Zhang, X. (2018) · Small · doi:10.1002/smll.201703321 · Cited by 90 · see citing works

A platinum prodrug conjugated with a photosensitizer with aggregation-induced emission (AIE) characteristics for drug activation monitoring and combinatorial photodynamic–chemotherapy against cisplatin resistant cancer cells

Yuan, Y., Zhang, C., & Liu, B. (2015) · Chemical Communications · doi:10.1039/c5cc01952d · Cited by 87 · see citing works

Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation

Yuan, Y., Xu, S., Zhang, C., Zhang, R., & Liu, B. (2015) · Journal of Materials Chemistry B · doi:10.1039/c5tb02270c · Cited by 85 · see citing works

MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery

Hu, J., Liu, L., Li, Z., et al. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02490k · Cited by 84 · see citing works

Specific Light‐Up Bioprobe with Aggregation‐Induced Emission and Activatable Photoactivity for the Targeted and Image‐Guided Photodynamic Ablation of Cancer Cells

Yuan, Y., Zhang, C., Gao, M., Zhang, R., Tang, B. Z., & Liu, B. (2014) · Angewandte Chemie · doi:10.1002/ange.201408476 · Cited by 81 · see citing works

The rational design of a gemcitabine prodrug with AIE-based intracellular light-up characteristics for selective suppression of pancreatic cancer cells

Han, H., Jin, Q., Wang, Y., Chen, Y., & Ji, J. (2015) · Chemical Communications · doi:10.1039/c5cc06654a · Cited by 77 · see citing works

A pH-responsive AIE nanoprobe as a drug delivery system for bioimaging and cancer therapy

Wang, H., Liu, G., Dong, S., Xiong, J., Du, Z., & Cheng, X. (2015) · Journal of Materials Chemistry B · doi:10.1039/c5tb01169h · Cited by 75 · see citing works

Light-responsive AIE nanoparticles with cytosolic drug release to overcome drug resistance in cancer cells

Yuan, Y., Xu, S., Zhang, C., & Liu, B. (2016) · Polymer Chemistry · doi:10.1039/c6py00449k · Cited by 70 · see citing works

Lipid Droplet‐Targetable Fluorescence Guided Photodynamic Therapy of Cancer Cells with an Activatable AIE‐Active Fluorescent Probe for Hydrogen Peroxide

Jiang, G., Li, C., Liu, X., Chen, Q., Li, X., Gu, X., Zhang, P., Lai, Q., & Wang, J. (2020) · Advanced Optical Materials · doi:10.1002/adom.202001119 · Cited by 70 · see citing works

Redox-Responsive Biomimetic Polymeric Micelle for Simultaneous Anticancer Drug Delivery and Aggregation-Induced Emission Active Imaging

Hu, J. X., Zhuang, W., Ma, B., Su, X., Yu, T., Li, G., Hu, Y., & Wang, Y. (2018) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.8b00119 · Cited by 65 · see citing works

Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells

Ji, S., Gao, H., Mu, W., Ni, X., Yi, X., Shen, J. Q., Liu, Q., Bao, P., & Ding, D. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb02685d · Cited by 64 · see citing works

Mesoporous silica nanoparticle facilitated drug release through cascade photosensitizer activation and cleavage of singlet oxygen sensitive linker

Lee, J., Park, J., Singha, K., et al. (2012) · Chemical Communications · doi:10.1039/c2cc38510d · Cited by 63 · see citing works

Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes

Padilla‐Parra, S., Matos, P. M., Kondo, N., Marin, M., Santos, N. C., & Melikyan, G. B. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211714109 · Cited by 61 · see citing works

‘AIE + ESIPT’ assisted photorelease: fluorescent organic nanoparticles for dual anticancer drug delivery with real-time monitoring ability

Biswas, S., Mengji, R., Barman, S., et al. (2017) · Chemical Communications · doi:10.1039/c7cc07692d · Cited by 59 · see citing works

Smart Probe for Tracing Cancer Therapy: Selective Cancer Cell Detection, Image-Guided Ablation, and Prediction of Therapeutic Response In Situ

Yuan, Y., Kwok, R. T. K., Tang, B. Z., & Liu, B. (2015) · Small · doi:10.1002/smll.201501498 · Cited by 57 · see citing works

MnO2-DNAzyme-photosensitizer nanocomposite with AIE characteristic for cell imaging and photodynamic-gene therapy

Wang, X., Dai, J., Wang, X., Hu, Q., Huang, K., Zhao, Z., Lou, X., & Xia, F. (2019) · Talanta · doi:10.1016/j.talanta.2019.05.003 · Cited by 56 · see citing works

Tumor-microenvironment controlled nanomicelles with AIE property for boosting cancer therapy and apoptosis monitoring

Qian, Y., Wang, Y., Jia, F., Wang, Z., Yue, C., Zhang, W., Hu, Z., & Wang, W. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.10.003 · Cited by 55 · see citing works

AIE Luminogen‐Functionalized Hollow Mesoporous Silica Nanospheres for Drug Delivery and Cell Imaging

Fan, Z., Li, D., Yu, X. L., Zhang, Y., Cai, Y., Jin, J., & Yu, J. (2015) · Chemistry - A European Journal · doi:10.1002/chem.201504377 · Cited by 51 · see citing works

β-galactosidase responsive AIE fluorogene for identification and removal of senescent cancer cells

Gao, Z., Gao, H., Zheng, D., Xu, T., Chen, Y., Liang, C., Wang, L., Ding, D., & Yang, Z. (2020) · Science China Chemistry · doi:10.1007/s11426-019-9659-2 · Cited by 43 · see citing works

Enzyme-Responsive Peptide-Based AIE Bioprobes

Yang, J., Wei, J., Luo, F., Dai, J., Hu, J., Lou, X., & Xia, F. (2020) · Topics in Current Chemistry · doi:10.1007/s41061-020-00311-9 · Cited by 43 · see citing works

A Multifunctional Peptide‐Conjugated AIEgen for Efficient and Sequential Targeted Gene Delivery into the Nucleus

Cheng, Y., Sun, C., Liu, R., Yang, J., Dai, J., Zhai, T., Lou, X., & Xia, F. (2019) · Angewandte Chemie · doi:10.1002/ange.201901527 · Cited by 43 · see citing works

AIEgen based drug delivery systems for cancer therapy

Dong, Y., Liu, B., & Yuan, Y. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.09.028 · Cited by 41 · see citing works

Promising Applications of AIEgens in Animal Models

He, B., Situ, B., Zhao, Z., & Zheng, L. (2019) · Small Methods · doi:10.1002/smtd.201900583 · Cited by 41 · see citing works

Combination of [12]aneN3 and Triphenylamine-Benzylideneimidazolone as Nonviral Gene Vectors with Two-Photon and AIE Properties

Liu, M., Ma, L., Liu, X., Liu, J., Lu, Z., Liu, R., & He, L. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b15169 · Cited by 37 · see citing works

Two-photon AIE luminogen labeled multifunctional polymeric micelles for theranostics

Zhuang, W., Ma, B., Hu, J. X., Jiang, J., Li, G., Li, Y., & Wang, Y. (2019) · Theranostics · doi:10.7150/thno.33901 · Cited by 35 · see citing works

In Situ Probing Intracellular Drug Release from Redox‐Responsive Micelles by United FRET and AIE

Wang, X., Li, J., Yan, Q., Chen, Y., Fan, A., Wang, Z., & Zhao, Y. (2018) · Macromolecular Bioscience · doi:10.1002/mabi.201700339 · Cited by 31 · see citing works

Self-assembled core–shell-corona multifunctional non-viral vector with AIE property for efficient hepatocyte-targeting gene delivery

Wang, B., Chen, P., Zhang, J., et al. (2017) · Polymer Chemistry · doi:10.1039/c7py01520h · Cited by 30 · see citing works

Enzyme Databases

Schomburg, D., & Schomburg, I. (2009) · Methods in molecular biology · doi:10.1007/978-1-60327-241-4_7 · Cited by 22 · see citing works

Chemically modified nucleic acid biopolymers used in biosensing

Zhang, L., Yang, Y., Tan, J., & Yuan, Q. (2020) · Materials Chemistry Frontiers · doi:10.1039/d0qm00026d · Cited by 21 · see citing works

Notch1 increases Snail expression under high reactive oxygen species conditions in hepatocellular carcinoma cells

Kim, H. S., & Jung, G. (2014) · Free Radical Research · doi:10.3109/10715762.2014.909595 · Cited by 20 · see citing works

Single-Component Fluorescent Organic Nanoparticles with Four-Armed Phototriggers for Chemo-Photodynamic Therapy and Cellular Imaging

Chokkalingam, P., Pavithra, M. K., Reddy, L. V. K., et al. (2019) · ACS Applied Nano Materials · doi:10.1021/acsanm.9b00630 · Cited by 20 · see citing works

pH-Responsive Tumor-Targetable Theranostic Nanovectors Based on Core Crosslinked (CCL) Micelles with Fluorescence and Magnetic Resonance (MR) Dual Imaging Modalities and Drug Delivery Performance

Tian, S.-D., Liu, G., Wang, X.-R., Zhang, G., & Hu, J.-M. (2016) · Polymers · doi:10.3390/polym8060226 · Cited by 19 · see citing works

Near-infrared AIEgen-functionalized and diselenide-linked oligo-ethylenimine with self-sufficing ROS to exert spatiotemporal responsibility for promoted gene delivery

Huang, Y., Chen, Q., Lu, H., An, J., Zhu, H., Yan, X., Li, W., & Gao, H. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb02207k · Cited by 18 · see citing works

H 2 O 2 -responsive polymeric micelles with a benzil moiety for efficient DOX delivery and AIE imaging

Dai, Y.-D., Sun, X., Sun, W. F., et al. (2019) · Organic & Biomolecular Chemistry · doi:10.1039/c9ob00859d · Cited by 17 · see citing works

Macrocyclic polyamine [12]aneN 3 modified triphenylamine-pyrazine derivatives as efficient non-viral gene vectors with AIE and two-photon imaging properties

Ma, L., Liu, M., Liu, X., Sun, W. F., Lu, Z., Gao, Y., & He, L. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00321b · Cited by 16 · see citing works

Redox-responsive AIE micelles for intracellular paclitaxel delivery

Wang, Q., Gao, F., & Zhou, X. (2020) · Colloid & Polymer Science · doi:10.1007/s00396-020-04679-4 · Cited by 14 · see citing works

Review on recent trends and prospects in π‐conjugated luminescent aggregates for biomedical applications

Barman, D., Narang, K., Parui, R., Zehra, N., Khatun, M. N., Adil, L. R., & Iyer, P. K. (2022) · Aggregate · doi:10.1002/agt2.172 · Cited by 113 · see citing works

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Towards meso ‐Ester BODIPYs with Aggregation‐Induced Emission Properties: The Effect of Substitution Positions

Chua, M. H., Ni, Y. Z., Garai, M., Zheng, B., Huang, K., Xu, Q., Xu, J., & Wu, J. (2015) · Chemistry - An Asian Journal · doi:10.1002/asia.201500420 · Cited by 43 · see citing works

New aggregation-induced delayed fluorescent materials for efficient OLEDs with high stabilities of emission color and efficiency

Chen, H., Liu, H., Xiong, Y., He, J., Zhao, Z., & Tang, B. Z. (2022) · Materials Chemistry Frontiers · doi:10.1039/d1qm01625c · Cited by 15 · see citing works