Genetic architecture for human aggression: A study of gene–phenotype relationship in OMIM
Open accessAbstract
Genetic studies of human aggression have mainly focused on known candidate genes and pathways regulating serotonin and dopamine signaling and hormonal functions. These studies have taught us much about the genetics of human aggression, but no genetic locus has yet achieved genome‐significance. We here present a review based on a paradoxical hypothesis that studies of rare, functional genetic variations can lead to a better understanding of the molecular mechanisms underlying complex multifactorial disorders such as aggression. We examined all aggression phenotypes catalogued in Online Mendelian Inheritance in Man (OMIM), an Online Catalog of Human Genes and Genetic Disorders. We identified 95 human disorders that have documented aggressive symptoms in at least one individual with a well‐defined genetic variant. Altogether, we retrieved 86 causal genes. Although most of these genes had not been implicated in human aggression by previous studies, the most significantly enriched canonical pathways had been previously implicated in aggression (e.g., serotonin and dopamine signaling). Our findings provide strong evidence to support the causal role of these pathways in the pathogenesis of aggression. In addition, the novel genes and pathways we identified suggest additional mechanisms underlying the origins of human aggression. Genome‐wide association studies with very large samples will be needed to determine if common variants in these genes are risk factors for aggression. © 2015 Wiley Periodicals, Inc.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Studies of rare human genetic conditions and gene knockouts in mice show that many genetic determinants play critical roles in shaping the emotional circuitry of the brain and modulating aggressive behavior.
“Studies of rare human genetic conditions [14] and gene knockouts (KOs) in mice [15, 16] show that many genetic determinants play critical roles in shaping the emotional circuitry of the brain and modulating aggressive behavior [17, 18].”
From An integrated analysis of genes and functional pathways for aggression in human and rodent models (2019) · cites this paper as [14]
Several recent reviews in human and animals have consistently identified these pathways.
“Indeed, several recent reviews in human and animals have consistently identified these pathways [11, 15, 51].”
From An integrated analysis of genes and functional pathways for aggression in human and rodent models (2019) · cites this paper as [51]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Part of this paper’s reference list could not be split into single entries.
Hierarchical Organization of Modularity in Metabolic Networks
Ravasz, E., Somera, A. L., Mongru, D. A., Oltvai, Z. N., & Barabási, A.-L. (2002) · Science · doi:10.1126/science.1073374 · Cited by 4,224 · see citing works
(2013) · The Lancet · doi:10.1016/s0140-6736(12)62129-1 · Cited by 3,010 · see citing works
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013) · Nature Genetics · doi:10.1038/ng.2711 · Cited by 2,263 · see citing works
Self-citationAbnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
Brunner, H. G., Nelen, M., Breakefield, X. O., Ropers, H. H., & van Oost, B. A. (1993) · Science · doi:10.1126/science.8211186 · Cited by 1,644 · see citing works
Guidotti, A., Auta, J., Davis, J. M., Gerevini, V. D. G., Dwivedi, Y., Grayson, D. R., Impagnatiello, F., Pandey, G. N., Pesold, C., Sharma, R. P., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.11.1061 · Cited by 1,203 · see citing works
A human phenome-interactome network of protein complexes implicated in genetic disorders
Lage, K., Karlberg, E., Størling, Z. M., Olason, P., Pedersen, A., Rigina, O., Hinsby, A., Tümer, Z., Pociot, F., Tommerup, N., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1295 · Cited by 973 · see citing works
Enhanced Aggressive Behavior in Mice Lacking 5-HT 1B Receptor
Saudou, F., Amara, D. A., Dierich, A., LeMeur, M., Ramboz, S., Ségu, L., Buhot, M.-C., & Hen, R. (1994) · Science · doi:10.1126/science.8091214 · Cited by 839 · see citing works
McKusick, V. A. (1998) · Johns Hopkins University Press eBooks · doi:10.56021/9780801857423 · Cited by 769 · see citing works
The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
Lichtenstein, P., Carlström, E., Råstam, M., Gillberg, C., & Anckarsäter, H. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10020223 · Cited by 738 · see citing works
Genetic and environmental architecture on human aggression.
Miles, D. R., & Carey, G. (1997) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.72.1.207 · Cited by 490 · see citing works
Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Constortium, I. I. B. D. G., Cotsapas, C., & Daly, M. J. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1001273 · Cited by 438 · see citing works
Genetic and environmental architecture on human aggression.
Miles, D. R., & Carey, G. (1997) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.72.1.207 · Cited by 414 · see citing works
Fatemi, S. H., Stary, J. M., Earle, J. A., Araghi‐Niknam, M., & Eagan, E. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.02.017 · Cited by 300 · see citing works
Urban, D., Pöss, J., Böhm, M., & Laufs, U. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.07.056 · Cited by 287 · see citing works
Vassos, E., Collier, D. A., & Fazel, S. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.31 · Cited by 234 · see citing works
Protein interactome reveals converging molecular pathways among autism disorders
Sakai, Y., Shaw, C. A., Dawson, B. C., Dugas, D. V., Al-Mohtaseb, Z., Hill, D. E., & Zoghbi, H. Y. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002166 · Cited by 226 · see citing works
Clinical Assessment of Irritability, Aggression, and Apathy in Huntington and Alzheimer Disease
Burns, A. S., Folstein, S. E., Brandt, J., & Folstein, M. F. (1990) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199001000-00004 · Cited by 194 · see citing works
Alten, R., Gómez-Reino, J. J., Durez, P., Beaulieu, A. D., Sebba, A. I., Krammer, G., Preiss, R., Arulmani, U., Widmer, A., Gitton, X., et al. (2011) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-12-153 · Cited by 153 · see citing works
Ma, H., Zhao, X., Yuan, Y., & Zeng, A. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth167 · Cited by 152 · see citing works
Genetics of aggressive behavior: An overview
Veroude, K., Zhang‐James, Y., Fernàndez‐Castillo, N., Bakker, M. J., Cormand, B., & Faraone, S. V. (2016) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32364 · Cited by 147 · see citing works
Self-citationNetworks of Neuronal Genes Affected by Common and Rare Variants in Autism Spectrum Disorders
Ben-David, E., & Shifman, S. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002556 · Cited by 145 · see citing works
Sokol, D. K., Chen, D., Farlow, M. R., Dunn, D. W., Maloney, B., Zimmer, J. A., & Lahiri, D. K. (2006) · Journal of Child Neurology · doi:10.1177/08830738060210062201 · Cited by 120 · see citing works
Revisiting the Relationship Between Autism and Schizophrenia: Toward an Integrated Neurobiology
de Lacy, N., & King, B. H. (2013) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050212-185627 · Cited by 98 · see citing works
The Association Between Psychiatric Diagnoses and Severe Behavior Problems in Mental Retardation
Rojahn, J., Borthwick-Duffy, S. A., & Jacobson, J. W. (1993) · Annals of Clinical Psychiatry · doi:10.3109/10401239309148980 · Cited by 93 · see citing works
Is bipolar disorder specifically associated with aggression?
Ballester, J., Goldstein, T. R., Goldstein, B. I., Obreja, M., Axelson, D., Monk, K., Hickey, M. B., Iyengar, S., Farchione, T. R., Kupfer, D. J., et al. (2012) · Bipolar Disorders · doi:10.1111/j.1399-5618.2012.01006.x · Cited by 86 · see citing works
Adamczyk, A. L., Mejı́as, R., Takamiya, K., Yocum, J., Krasnova, I. N., Calderón, J. F., Cadet, J. L., Huganir, R. L., Pletnikov, M. V., & Wang, T. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.01.007 · Cited by 85 · see citing works
Cha, J., Fekete, T., Siciliano, F., Biezonski, D., Greenhill, L., Pliszka, S. R., Blader, J. C., Krain Roy, A., Leibenluft, E., & Posner, J. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.18 · Cited by 75 · see citing works
Philips, A. K., Sirén, A., Avela, K., Somer, M., Peippo, M. M., Ahvenainen, M., Doagu, F., Arvio, M., Kääriäinen, H., Esch, H. V., et al. (2014) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-9-49 · Cited by 75 · see citing works
Lee, S., Lemere, C. A., Frost, J. L., & Shea, T. B. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-111025 · Cited by 68 · see citing works
Aggression in Huntington's Disease: A Systematic Review of Rates of Aggression and Treatment Methods
Fisher, C. A., Sewell, K., Brown, A., & Churchyard, A. (2014) · Journal of Huntington s Disease · doi:10.3233/jhd-140127 · Cited by 61 · see citing works
Seo, T.-B., Cho, H.-S., Shin, M., Kim, C., Ji, E., & Baek, S. (2013) · Journal of Exercise Rehabilitation · doi:10.12965/jer.130003 · Cited by 61 · see citing works
Computational and systems biology in trauma and sepsis: current state and future perspectives.
An, G. C., Nieman, G. F., & Vodovotz, Y. (2012) · PubMed · Cited by 55 · see citing works
Lanz, T. A., Guilmette, E., Gosink, M. M., Fischer, J. E., Fitzgerald, L. W., Stephenson, D. T., & Pletcher, M. T. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-45 · Cited by 52 · see citing works
Oh, Y., Lee, J. E., Lee, P. H., & Kim, J. (2015) · Journal of Movement Disorders · doi:10.14802/jmd.14019 · Cited by 47 · see citing works
Anti-PCSK9 therapies for the treatment of hypercholesterolemia
Hooper, A. J., & Burnett, J. R. (2012) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2012.748743 · Cited by 46 · see citing works
Genes and Gene Networks Implicated in Aggression Related Behaviour
Malki, K., Pain, O., Du Rietz, E., Tosto, M. G., Paya-Cano, J., Sandnabba, K. N., de Boer, S., Schalkwyk, L. C., & Sluyter, F. (2014) · neurogenetics · doi:10.1007/s10048-014-0417-x · Cited by 33 · see citing works
Schlesinger, N. (2012) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2012.705825 · Cited by 26 · see citing works
Verma, D., Eriksson, P., Sahdo, B., Persson, A., Ejdebäck, M., Särndahl, E., & Söderkvist, P. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27489 · Cited by 24 · see citing works
Sharma, A., Chavali, S., Mahajan, A., Tabassum, R., Banerjee, V., Tandon, N., & Bharadwaj, D. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500024-mcp200 · Cited by 24 · see citing works
Aggressive Behavior in Schizophrenia: Relationship to Age of Onset and Cortical Atrophy
Sandyk, R. (1993) · International Journal of Neuroscience · doi:10.3109/00207459308994254 · Cited by 13 · see citing works
Canakinumab relieves gout flares when treatment options are limited
Onuora, S. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.90 · Cited by 4 · see citing works
Testosterone and explosive aggression in autism spectrum disorders.
Pivovarciova, A., Hnilicová, S., Ostatníková, D., & Mace, F. C. (2014) · PubMed · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Fairchild, G. F., Hawes, D. J., Frick, P. J., Copeland, W., Odgers, C. L., Franke, B., Freitag, C. M., & Brito, S. A. D. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0095-y · Cited by 426 · see citing works
Understanding zebrafish aggressive behavior
Zabegalov, K. N., Kolesnikova, T. O., Khatsko, S. L., Volgin, A. D., Yakovlev, O. A., Amstislavskaya, T. G., Friend, A. J., Bao, W., Alekseeva, P. A., Lakstygal, A. M., et al. (2018) · Behavioural Processes · doi:10.1016/j.beproc.2018.11.010 · Cited by 98 · see citing works
An integrated analysis of genes and functional pathways for aggression in human and rodent models
Zhang-James, Y., Fernàndez-Castillo, N., Hess, J. L., Malki, K., Glatt, S. J., Cormand, B., & Faraone, S. V. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0068-7 · Cited by 98 · see citing works
Self-citationOppositional defiant disorder: current insight
Ghosh, A., Ray, A., & Basu, A. (2017) · Psychology Research and Behavior Management · doi:10.2147/prbm.s120582 · Cited by 88 · see citing works
Genetic influences on conduct disorder
Salvatore, J. E., & Dick, D. M. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.034 · Cited by 76 · see citing works
Genetic association study of childhood aggression across raters, instruments, and age
Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., St Pourcain, B., Bolhuis, K., Palviainen, T., Zafarmand, H., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01480-x · Cited by 71 · see citing works
Odintsova, V. V., Roetman, P. J., Ip, H. F., Pool, R., van der Laan, C. M., Tona, K., Vermeiren, R. R. J. M., & Boomsma, D. I. (2019) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000239 · Cited by 44 · see citing works
Manchia, M., & Fanos, V. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.03.024 · Cited by 42 · see citing works
Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model
de Abreu, M. S., Giacomini, A. C. V. V., Genário, R., dos Santos, B. E., da Rosa, L. G., Demin, K. A., Wappler-Guzzetta, E. A., & Kalueff, A. V. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.01.044 · Cited by 40 · see citing works
Balázsfi, D., Zelena, D., Demeter, K., Miskolczi, C., Varga, Z. K., Nagyváradi, Á., Nyíri, G., Cserép, C., Baranyi, M., Sperlágh, B., et al. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00163 · Cited by 31 · see citing works
Manchia, M., Comai, S., Pinna, M., Pinna, F., Fanos, V., Denovan‐Wright, E. M., & Carpiniello, B. (2019) · Advances in clinical chemistry · doi:10.1016/bs.acc.2019.07.004 · Cited by 26 · see citing works
Boomsma, D. I. (2015) · Journal of pediatric and neonatal individualized medicine · doi:10.7363/040251 · Cited by 23 · see citing works
Emerging roles of Fgf14 in behavioral control
Hoxha, E., Marcinnò, A., Montarolo, F., Masante, L., Balbo, I., Ravera, F., Laezza, F., & Tempia, F. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.08.034 · Cited by 22 · see citing works
The biology of aggressive behavior in bipolar disorder: A systematic review
Fico, G., Anmella, G., Pacchiarotti, I., Verdolini, N., Sagué‐Vilavella, M., Corponi, F., Manchia, M., Vieta, E., & Murru, A. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.015 · Cited by 21 · see citing works
Taurine-mediated aggression is abolished via 5-HT1A antagonism and serotonin depletion in zebrafish
Mezzomo, N. J., Müller, T. E., Franscescon, F., Michelotti, P., Souza, T. P., Rosemberg, D. B., & Barcellos, L. J. G. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173067 · Cited by 19 · see citing works
The genetics of aggression: Where are we now?
Asherson, P. J., & Cormand, B. (2016) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32450 · Cited by 17 · see citing works
van Donkelaar, M. M. J., Hoogman, M., Shumskaya, E., Buitelaar, J. K., Bralten, J., & Franke, B. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.11.016 · Cited by 17 · see citing works
Rare copy number variation in extremely impulsively violent males
Vevera, J., Zarrei, M., Hartmannová, H., Jedličková, I., Mušálková, D., Přistoupilová, A., Oliveriusová, P., Trešlová, H., Nosková, L., Hodaňová, K., et al. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12536 · Cited by 15 · see citing works
Behavioral neuroscience in zebrafish: unravelling the complexity of brain-behavior relationships
Firdous, S. M., Pal, S., Khanam, S., & Zakir, F. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03275-5 · Cited by 14 · see citing works
Qadeer, M. I., Amar, A., Huang, Y., Min, E., Galfalvy, H., Hasnain, S., & Mann, J. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-81198-4 · Cited by 14 · see citing works
Genetic Association Study of Childhood Aggression across raters, instruments and agePreprint
Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez‐Mora, C., Nolte, I. M., Pourcain, B. S., Bolhuis, K., Palviainen, T., Zafarmand, M. H., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/854927 · Cited by 12 · see citing works
Cherepkova, E. V., Maksimov, V. V., & Aftanas, L. I. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0298-0 · Cited by 11 · see citing works
Comparative mRNA analysis of behavioral and genetic mouse models of aggression
Malki, K., Tosto, M. G., Pain, O., Sluyter, F., Mineur, Y. S., Crusio, W. E., de Boer, S., Sandnabba, K. N., Kesserwani, J., Robinson, E., et al. (2016) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32424 · Cited by 10 · see citing works
A systematic review of the etiology and neurobiology of intermittent explosive disorder
Paliakkara, J., Ellenberg, S., Ursino, A., Smith, A. A., Evans, J., Strayhorn, J. M., Faraone, S. V., & Zhang‐James, Y. (2025) · Psychiatry Research · doi:10.1016/j.psychres.2025.116410 · Cited by 10 · see citing works
Self-citationFernàndez‐Castillo, N., Cabana‐Domínguez, J., Kappel, D. B., Torrico, B., Weber, H., Lesch, K., Lao, Ó., Reif, A., & Cormand, B. (2021) · Genes · doi:10.3390/genes13010093 · Cited by 9 · see citing works
Mathai, A. J., Lowry, C. A., Cook, T. B., Brenner, L. A., Brundin, L., Groer, M. E., Peng, X., Giegling, I., Hartmann, A. M., Konte, B., et al. (2016) · Pteridines · doi:10.1515/pterid-2016-0006 · Cited by 8 · see citing works
Genetics and epigenetics of human aggression
Odintsova, V. V., Hagenbeek, F. A., van der Laan, C. M., van de Weijer, S. G. A., & Boomsma, D. I. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-12-821375-9.00005-0 · Cited by 11 · see citing works
Identification of key pathways and genes responsible for aggressive behavior
Uddin, N., Hussain, M., Rauf, I., & Zaidi, S. F. (2020) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2020.107349 · Cited by 3 · see citing works
Behavioral Genetics in Antisocial Spectrum Disorders with Particular Attention to Epigenetics
Gunter, T. D., & Judd, S. (2020) · Wiley eBooks · doi:10.1002/9781119159322.ch8 · Cited by 3 · see citing works
Валерьевна, К. И., Степанович, Р. В., & Lakhman, О. L. (2021) · Hygiene and Sanitation · doi:10.47470/0016-9900-2021-100-12-1462-1466 · Cited by 2 · see citing works
Neuropharmacology of Aggression in Model Systems: The Zebrafish as a New Narrative
de Abreu, M. S., Demin, K. A., Costa, F. V., Zabegalov, K. N., Giacomini, A. C. V. V., & Kalueff, A. V. (2023) · Springer eBooks · doi:10.1007/978-3-030-98711-4_141-1 · Cited by 1 · see citing works
Graw, J. (2020) · Springer eBooks · doi:10.1007/978-3-662-60909-5_15 · Cited by 1 · see citing works
Impact of Dietary Composition on Behavioral Expression and Gut Microbiome Dynamics in ZebrafishPreprint
Ramachandran, B., Sivarajan, D., Pothayi, V., & Devasia, S. C. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5120466 · Cited by 1 · see citing works
Graw, J. (2015) · Springer eBooks · doi:10.1007/978-3-662-44817-5_15
Neuropharmacology of Aggression in Model Systems: The Zebrafish as a New Narrative
de Abreu, M. S., Demin, K. A., Costa, F. V., Zabegalov, K. N., Giacomini, A. C. V. V., & Kalueff, A. V. (2023) · Springer eBooks · doi:10.1007/978-3-031-31547-3_141
Psychological characteristics of adolescents prone to suicidal behavior
Andronnikova, O. O. (2024) · General question of world science · doi:10.18411/gqws-01-2024-04
An Integrated, Multi-Level Approach to Interpersonal Aggression and Family Violence
Michalski, J. H. (2024) · Athens Journal of Social Sciences · doi:10.30958/ajss.11-2-1
Aspectos de las ciencias OMICs en la neurobiología del comportamiento agresivo humano
de Sousa, G. D., & de Oliveira, M. S. (2024) · Research Society and Development · doi:10.33448/rsd-v13i12.47808
Przydacz, M., Russo, G. I., Osman, N. I., Rivas, J. G., Rajwa, P., Werneburg, G. T., Anis, O., CILLIS, S. D., Guillot‐Tantay, C., Tutolo, M., et al. (2025) · International Journal of Impotence Research · doi:10.1038/s41443-025-01065-y
Xie, L., Wang, X., Chen, X., Zhai, P.-P., Xu, X. L., Shen, X., & Wang, J.-J. (2025) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2025.100618
Odintsova, V. V., van der Laan, C. M., Hagenbeek, F. A., & Boomsma, D. I. (2025) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0029809
Ehrenhofer‐Murray, A. E. (2025) · Springer eBooks · doi:10.1007/978-3-662-70328-1_15
Mo, J., Yang, H., Zhao, E., Wang, Z., & Ge, C. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6210868
Mo, J., Yang, H., Zhao, E., Wang, Z., & Ge, C. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6510365
Mo, J., Zhao, E., Wang, Z., Ge, C., & Yang, H. (2026) · Comparative Biochemistry and Physiology Part D Genomics and Proteomics · doi:10.1016/j.cbd.2026.101975
Sex Differences in Aggressive Traits and Superior Temporal Cortical Responses to Monetary Loss
Li, G., Yingjie, C., Yang, Y., Zhang, X., Li, B., Sun, H., Huang, S., Gao, M., Bin, G., & Li, C.-S. R. (2026) · Behavioral Sciences · doi:10.3390/bs16101778
- Authors
- Zhang‐James, Y., & Faraone, S. V.
- Affiliations
- SUNY Upstate Medical University (US)
- Corresponding author
- Faraone, Stephen V.
- Venue
- American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
- Publisher
- Wiley
- Published
- 2015-08-19
- Volume
- 171
- Issue
- 5
- Pages
- 641-649
- ISSN
- 1552-4841 (ISSN-L)
- 1552-485X
- OpenAlex
- W2144545031
- Cited by
- 48
- References
- 42
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 6 · 2023: 3 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 6 · 2017: 3 · 2016: 4 · 2015: 2
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Medical Genetics Part B Neuropsychiatric Genetics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH094469, R13MH059126)
- .G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway, the European Community's Seventh Framework Programme (FP7/2007-2013)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- human aggression, genetic architecture, genotype-phenotype correlation, OMIM, rare variants, serotonin signaling, dopamine signaling, canonical pathways, complex diseases
- MeSH terms
- Aggression, Humans, Risk Factors, Genetic Variation, Genetic Predisposition to Disease, Databases, Genetic, Genome-Wide Association Study, Genetic Association Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
