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Apolipoprotein E Genotype and Deposits of Aβ40 and Aβ42 in Alzheimer Disease

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Amyloid (Aβ) deposition in chromosome 1–linked Alzheimer's disease: The volga german families

Mann, D. M. A., Iwatsubo, T., Nochlin, D., Sumi, S. M., Levy‐Lahad, E., & Bird, T. D. (1997) · Annals of Neurology · doi:10.1002/ana.410410110 · Cited by 51

Presenilin Affects Arm/β-Catenin Localization and Function in Drosophila

Noll, E., Medina, M., Hartley, D. M., Zhou, J., Perrimon, N., & Kosik, K. S. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9925 · Cited by 50

MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice

Liu, B., Frost, J. L., Sun, J., Fu, H., Grimes, S., Blackburn, P., & Lemere, C. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5924-12.2013 · Cited by 50

Review

Verbeek, M. M., Ruiter, D. J., & de Waal, R. M. W. (1997) · Biological Chemistry · doi:10.1515/bchm.1997.378.9.937 · Cited by 49

Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome

Lee, J. H., Chulikavit, M., Pang, D. I., Zigman, W. B., Silverman, W. P., & Schupf, N. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.08.042 · Cited by 46

A novel missense mutation in the presenilin-1 gene in a familial Alzheimer's disease pedigree with abundant amyloid angiopathy

Yasuda, M., Maeda, K., Ikejiri, Y., Kawamata, T., Kuroda, S., & Tanaka, C. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00569-7 · Cited by 49

Presenilin‐1 protein expression in familial and sporadic Alzheimer's disease

Levey, A. I., Heilman, C. J., Lah, J. J., Nash, N. R., Rees, H. D., Wakai, M., Mirra, S. S., Rye, D. B., Nochlin, D., Bird, T. D., et al. (1997) · Annals of Neurology · doi:10.1002/ana.410410610 · Cited by 45

Evidence That Aβ42 Plasma Levels in Presenilin-1 Mutation Carriers Do not Allow for Prediction of Their Clinical Phenotype

Jonghe, C. D., Cras, P. P., Vanderstichele, H., Cruts, M., Vanderhoeven, I., Smouts, I., Vanmechelen, E., Martin, J.-J., Hendriks, L., & Broeckhoven, C. V. (1999) · Neurobiology of Disease · doi:10.1006/nbdi.1999.0247 · Cited by 45

Increased Aβ 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 gene

Ishii, K., Ii, K., Hasegawa, T., Shoji, S., Doi, A., & Mori, H. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00347-9 · Cited by 44

Deposition of β-Amyloid Subtypes 40 and 42 Differentiates Dementia With Lewy Bodies From Alzheimer Disease

Lippa, C. F., Ozawa, K., Mann, D. M. A., Ishii, K., Smith, T. W., Arawaka, S., & Mori, H. (1999) · Archives of Neurology · doi:10.1001/archneur.56.9.1111 · Cited by 44

Rank-Order of Potencies for Inhibition of the Secretion of Aβ40 and Aβ42 Suggests That Both Are Generated by a Single γ-Secretase

Durkin, J. T., Murthy, S., Husten, E. J., Trusko, S. P., Savage, M. J., Rotella, D. P., Greenberg, B., & Siman, R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.29.20499 · Cited by 43

Localization of β-Secretase Memapsin 2 in the Brain of Alzheimer's Patients and Normal Aged Controls

Sun, A., Koelsch, G., Tang, J., & Bing, G. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7875 · Cited by 42

Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin‐1 gene show an unusual but characteristic β‐amyloid pathology known as ‘cotton wool’ plaques

Mann, D. M. A., Takeuchi, A., Sato, S., Cairns, N. J., Lantos, P. L., Rossor, M. N., Haltia, M., Kalimo, H., & Iwatsubo, T. (2001) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2001.00316.x · Cited by 42

Proteasome Inhibitors Prevent the Degradation of Familial Alzheimer’s Disease-Linked Presenilin 1 and Potentiate Aβ42 Recovery from Human Cells

Marambaud, P., Ancolio, K., Lopez‐Perez, E., & Checler, F. (1998) · Molecular Medicine · doi:10.1007/bf03401912 · Cited by 64

Tau load is associated with apolipoprotein E genotype and the amount of amyloid β protein, Aβ40, in sporadic and familial Alzheimer's disease

Thaker, U., McDonagh, A. M., Iwatsubo, T., Lendon, C. L., Pickering-Brown, S. M., & Mann, D. M. A. (2003) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2003.00425.x · Cited by 39

Cholesterol supplementation with egg yolk increases plasma cholesterol and decreases plasma 7-dehydrocholesterol in Smith-Lemli-Opitz syndrome

Linck, L. M., Lin, D. S., Flavell, D. P., CONNOR, W. E., & Steiner, R. D. (2000) · American Journal of Medical Genetics · doi:10.1002/1096-8628(20000828)93:5 · Cited by 66

Time Course of Glucose Metabolism in Relation to Cognitive Performance and Postmortem Neuropathology in Met146Val PSEN1 Mutation Carriers

Schöll, M., Almkvist, O., Bogdanović, N., Wall, A. E., Långström, B., Viitanen, M. H., & Nordberg, A. K. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-101563 · Cited by 35

Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation

Singleton, A. B. (2000) · Brain · doi:10.1093/brain/123.12.2467 · Cited by 36

The Functions of the Amyloid Precursor Protein Gene

Panegyres, P. K. (2001) · Reviews in the Neurosciences · doi:10.1515/revneuro.2001.12.1.1 · Cited by 36

Aberrant Presenilin-1 Expression Downregulates LDL Receptor-Related Protein (LRP): Is LRP Central to Alzheimer's Disease Pathogenesis?

Van Uden, E., Carlson, G., St. George-Hyslop, P., Westaway, D., Orlando, R., Mallory, M., Rockenstein, E., & Masliah, E. (1999) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1999.0772 · Cited by 32

Neuroprotective effect of mogrol against Aβ1–42-induced memory impairment neuroinflammation and apoptosis in mice

Chen, G., Liu, C., Meng, G., Zhang, C., Chen, F., Tang, S., Hong, H., & Zhang, C. (2018) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13056 · Cited by 34

Amyloid beta protein (A beta) deposition in chromosome 14-linked Alzheimer's disease: Predominance of A beta(42(43))

Mann, D., Iwatsubo, T., Cairns, N., Lantos, P., Nochlin, D., Sumi, S., Bird, T., Poorkaj, P., Hardy, J., Hutton, M., et al. (1996) · UCL Discovery (University College London)

Amyloid (Aβ) deposition in chromosome 1–linked Alzheimer's disease: The volga german families

Mann, D. M. A., Iwatsubo, T., Nochlin, D., Sumi, S. M., Levy‐Lahad, E., & Bird, T. D. (1997) · Annals of Neurology · doi:10.1002/ana.410410110 · Cited by 51

The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions

Keller, L., Welander, H., Chiang, H., Tjernberg, L. O., Nennesmo, I., Wallin, Å. K., & Graff, C. (2010) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.107 · Cited by 40

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease

Mann, D. M. A., Pickering-Brown, S. M., Takeuchi, A., & Iwatsubo, T. (2001) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64688-3 · Cited by 182

Apolipoprotein E Genotype and Deposits of Aβ40 and Aβ42 in Alzheimer Disease

McNamara, M. J., Gómez‐Isla, T., & Hyman, B. T. (1998) · Archives of Neurology · doi:10.1001/archneur.55.7.1001 · Cited by 55