Expression and roles of steroidogenic acute regulatory (StAR) protein in 'non-classical', extra-adrenal and extra-gonadal cells and tissues

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Pitt, B., Zannad, F., Remme, W. J., Cody, R., Castaigne, A., Perez, A., Palensky, J., & Wittes, J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411001 · Cited by 9,214 · see citing works

Adipose Tissue as an Endocrine Organ

Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0395 · Cited by 5,522 · see citing works

Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

Pitt, B., Remme, W., Zannad, F., Neaton, J., Martinez, F., Roniker, B., Bittman, R., Hurley, S., Kleiman, J., & Gatlin, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030207 · Cited by 4,941 · see citing works

Eplerenone in patients with systolic heart failure and mild symptoms

Zannad, F., McMurray, J. J. V., Krum, H., van Veldhuisen, D. J., Swedberg, K., Shi, H., Vincent, J., Pocock, S. J., & Pitt, B. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1009492 · Cited by 3,111 · see citing works

Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity

Sampson, J. A. (1927) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(15)30003-x · Cited by 2,334 · see citing works

The development of androgen-independent prostate cancer.

Feldman, B. J., & Feldman, D. (2001) · Nature reviews. Cancer · doi:10.1038/35094009 · Cited by 2,326 · see citing works

Molecular determinants of resistance to antiandrogen therapy

Chen, C. D., Welsbie, D. S., Tran, C., Baek, S. H., Chen, R., Vessella, R., Rosenfeld, M. G., & Sawyers, C. L. (2004) · Nature Medicine · doi:10.1038/nm972 · Cited by 2,278 · see citing works

A transgenic model of visceral obesity and the metabolic syndrome

Masuzaki, H., Paterson, J., Shinyama, H., Morton, N. M., Mullins, J. J., Seckl, J. R., & Flier, J. S. (2001) · Science · doi:10.1126/science.1066285 · Cited by 1,766 · see citing works

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

Payne, A. H., & Hales, D. B. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0030 · Cited by 1,766 · see citing works

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Janowski, B. A., Willy, P. J., Devi, T. R., Falck, J. R., & Mangelsdorf, D. J. (1996) · Nature · doi:10.1038/383728a0 · Cited by 1,754 · see citing works

Role of cholesterol and lipid organization in disease

Maxfield, F. R., & Tabas, I. A. (2005) · Nature · doi:10.1038/nature04399 · Cited by 1,298 · see citing works

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

Andersson, S., Davis, D. L., Dahlbäck, H., Jörnvall, H., & Russell, D. W. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83172-6 · Cited by 1,229 · see citing works

The purification, cloning and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)

Clark, B. J., Wells, J., King, S. R., & Stocco, D. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46930-x · Cited by 1,168 · see citing works

INCESSANT OVULATION—A FACTOR IN OVARIAN NEOPLASIA ?

Fathalla, M. F. (1971) · The Lancet · doi:10.1016/s0140-6736(71)92335-x · Cited by 1,135 · see citing works

Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer

Stanbrough, M., Bubley, G. J., Ross, K., Golub, T. R., Rubin, M. A., Penning, T. M., Febbo, P. G., & Balk, S. P. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4000 · Cited by 1,082 · see citing works

Regulation of the acute production of steroids in steroidogenic cells

STOCCO, D. M., & CLARK, B. J. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-3-221 · Cited by 1,057 · see citing works

Trends in the leading causes of death in the United States, 1970-2002.

Jemal, A., Ward, E. M., Hao, Y.-P., & Thun, M. (2005) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.294.10.1255 · Cited by 1,054 · see citing works

Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis

Lin, D., Sugawara, T., Strauss, J. F., Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A., & Miller, W. L. (1995) · Science · doi:10.1126/science.7892608 · Cited by 1,030 · see citing works

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

Venkateswaran, A., Laffitte, B. A., Joseph, S. B., Mak, P. A., Wilpitz, D. C., Edwards, P. A., & Tontonoz, P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.200367697 · Cited by 1,005 · see citing works

Oxysterols: Modulators of Cholesterol Metabolism and Other Processes

Schroepfer, G. J. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.1.361 · Cited by 965 · see citing works

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

Cole, T. J., Blendy, J. A., Monaghan, A. P., Krieglstein, K., Schmid, W., Aguzzi, A., Fantuzzi, G., Hummler, E., Unsicker, K., & Schütz, G. (1995) · Genes & Development · doi:10.1101/gad.9.13.1608 · Cited by 946 · see citing works

Glucocorticoids in T Cell Development and Function

Ashwell, J. D., Lu, F. W. M., & Vacchio, M. S. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.309 · Cited by 777 · see citing works

Aromatase—a brief overview

Simpson, E. R., Clyne, C., Rubin, G., Boon, W. C., Robertson, K., Britt, K., Speed, C., & Jones, M. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.081601.142703 · Cited by 773 · see citing works

Hormonal Etiology of Epithelial Ovarian Cancer, With a Hypothesis Concerning the Role of Androgens and Progesterone

Risch, H. A. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.23.1774 · Cited by 771 · see citing works

Endometriosis

Olive, D. L., & Schwartz, L. B. (1993) · New England Journal of Medicine · doi:10.1056/nejm199306173282407 · Cited by 675 · see citing works

Regulation of the acute production of steroids in steroidogenic cells

Stocco, D. M. (1996) · Endocrine Reviews · doi:10.1210/er.17.3.221 · Cited by 635 · see citing works

NEUROSTEROIDS: A NOVEL FUNCTION OF THE BRAIN

Baulieu, E. E. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00071-7 · Cited by 624 · see citing works

Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance

Holzbeierlein, J., Lal, P., LaTulippe, E., Smith, A., Satagopan, J., Zhang, L., Ryan, C., Smith, S., Scher, H., Scardino, P., et al. (2004) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63112-4 · Cited by 577 · see citing works

27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

Fu, X., Menke, J. G., Chen, Y., Zhou, G., MacNaul, K. L., Wright, S. D., Sparrow, C. P., & Lund, E. G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105805200 · Cited by 573 · see citing works

Neurosteroids: biochemistry and clinical significance

Mellon, S. H., & Griffin, L. D. (2002) · Trends in Endocrinology & Metabolism · doi:10.1016/s1043-2760(01)00503-3 · Cited by 538 · see citing works

Intraprostatic Androgens and Androgen-Regulated Gene Expression Persist after Testosterone Suppression: Therapeutic Implications for Castration-Resistant Prostate Cancer

Mostaghel, E. A., Page, S. T., Lin, D. W., Fazli, L., Coleman, I. M., True, L. D., Knudsen, B., Hess, D. L., Nelson, C. C., Matsumoto, A. M., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3332 · Cited by 529 · see citing works

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

Muglia, L., Jacobson, L., Dikkes, P., & Majzoub, J. A. (1995) · Nature · doi:10.1038/373427a0 · Cited by 524 · see citing works

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Morton, N. M., Paterson, J. M., Masuzaki, H., Holmes, M. C., Staels, B., Fievet, C., Walker, B. R., Flier, J. S., Mullins, J. J., & Seckl, J. R. (2004) · Diabetes · doi:10.2337/diabetes.53.4.931 · Cited by 512 · see citing works

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449 · see citing works

Myocardial Production of Aldosterone and Corticosterone in the Rat

Silvestre, J., Robert, V., Heymes, C., Aupetit, B., Mouas, C., Moalic, J., Bernard Swynghedauw, A., & Delcayre, C. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.9.4883 · Cited by 446 · see citing works

Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states

Rone, M. B., Fan, J., & Papadopoulos, V. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.03.001 · Cited by 399 · see citing works

Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Sugawara, T., Holt, J. A., Driscoll, D., Strauss, J. F., Lin, D., Miller, W. L., Patterson, D., Clancy, K. P., Hart, I. M., & Clark, B. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.4778 · Cited by 382 · see citing works

Neurosteroids: Expression of Steroidogenic Enzymes and Regulation of Steroid Biosynthesis in the Central Nervous System

Mensah‐Nyagan, A. G., do Rego, J. L., Beaujean, D., Luu-The, V., Pelletier, G., & Vaudry, H. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01395-4 · Cited by 379 · see citing works

Oxysterol biosynthetic enzymes

Russell, D. W. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00142-6 · Cited by 374 · see citing works

Monocyte recruitment and foam cell formation in atherosclerosis

Bobryshev, Y. V. (2005) · Micron · doi:10.1016/j.micron.2005.10.007 · Cited by 370 · see citing works

Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.

Cali, J. J., & Russell, D. W. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)89517-9 · Cited by 365 · see citing works

Fifty years of advances in bile acid synthesis and metabolism

Russell, D. W. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800026-jlr200 · Cited by 358 · see citing works

Rapid regulation of steroidogenesis by mitochondrial protein import

Bose, H. S., Lingappa, V. R., & Miller, W. L. (2002) · Nature · doi:10.1038/417087a · Cited by 357 · see citing works

Steroid production in the thymus: implications for thymocyte selection.

Vacchio, M. S., Papadopoulos, V. D., & Ashwell, J. D. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.6.1835 · Cited by 355 · see citing works

Protein Synthesis and Adrenocorticotropin Responsiveness

Ferguson, J. J. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67893-7 · Cited by 343 · see citing works

Epithelial-Mesenchymal Interactions in the Developing Lung

Shannon, J. M., & Hyatt, B. A. (2004) · Annual Review of Physiology · doi:10.1146/annurev.physiol.66.032102.135749 · Cited by 321 · see citing works

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.

Björkhem, I., Andersson, O., Diczfalusy, U., SEVASTIK, B. O., Xiu, R., Duan, C., & Lund, E. G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.18.8592 · Cited by 320 · see citing works

GLUCOCORTICOID AND MINERALOCORTICOID RECEPTORS: Biology and Clinical Relevance

Funder, M. (1997) · Annual Review of Medicine · doi:10.1146/annurev.med.48.1.231 · Cited by 320 · see citing works

Immediate Administration of Mineralocorticoid Receptor Antagonist Spironolactone Prevents Post-Infarct Left Ventricular Remodeling Associated With Suppression of a Marker of Myocardial Collagen Synthesis in Patients With First Anterior Acute Myocardial Infarction

Hayashi, M., Tsutamoto, T., Wada, A., Tsutsui, T., Ishii, C., Ohno, K., Fujii, M., Taniguchi, A., Hamatani, T., Nozato, Y., et al. (2003) · Circulation · doi:10.1161/01.cir.0000068340.96506.0f · Cited by 319 · see citing works

Glucocorticoids and Insulin Promote the Differentiation of Human Adipocyte Precursor Cells into Fat Cells

Hauner, H., Schmid, P., & PFEIFFER, E. F. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-4-832 · Cited by 312 · see citing works

Glucocorticoids and lung development in the fetus and preterm infant

Bolt, R. J., van Weissenbruch, M. M., Lafeber, H. N., & de Waal, H. A. D. (2001) · Pediatric Pulmonology · doi:10.1002/ppul.1092 · Cited by 304 · see citing works

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

Arakane, F., Sugawara, T., Nishino, H., Liu, Z., Holt, J. A., Pain, D., Stocco, D. M., Miller, W. L., & Strauss, J. F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13731 · Cited by 304 · see citing works

Prostaglandin E2 Stimulates Aromatase Expression in Endometriosis-Derived Stromal Cells

Noble, L. S. (1997) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.2.600 · Cited by 301 · see citing works

Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1)

Thiboutot, D., Gilliland, K., Cong, Z., Jabara, S., McAllister, J. M., Sivarajah, A., & Clawson, G. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12244.x · Cited by 301 · see citing works

Androgens and hair growth

Randall, V. A. (2008) · Dermatologic Therapy · doi:10.1111/j.1529-8019.2008.00214.x · Cited by 297 · see citing works

Inflammation and ovarian cancer

Macciò, A., & Madeddu, C. (2012) · Cytokine · doi:10.1016/j.cyto.2012.01.015 · Cited by 295 · see citing works

Progesterone Receptor Plays a Major Antiinflammatory Role in Human Myometrial Cells by Antagonism of Nuclear Factor-κB Activation of Cyclooxygenase 2 Expression

Hardy, D. B., Janowski, B. A., Corey, D. R., & Mendelson, C. R. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0112 · Cited by 289 · see citing works

Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma

Montero, J., Morales, A., Llacuna, L., Lluis, J. M., Terrones, O., Basáñez, G., Antonsson, B. E., Prìeto, J., García‐Ruiz, C., Colell, A., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6161 · Cited by 276 · see citing works

Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Keinan, N., Tyomkin, D., & Shoshan‐Barmatz, V. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00165-10 · Cited by 269 · see citing works

Complex Actions of Sex Steroids in Adipose Tissue, the Cardiovascular System, and Brain: Insights from Basic Science and Clinical Studies

Turgeon, J. L., Carr, M. C., Maki, P. M., Mendelsohn, M. E., & Wise, P. M. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0020 · Cited by 263 · see citing works

Progestational Agents in the Treatment of Carcinoma of the Endometrium

Kelley, R. M., & Baker, W. H. (1961) · New England Journal of Medicine · doi:10.1056/nejm196102022640503 · Cited by 258 · see citing works

The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors

Stocco, D. M., & Sodeman, T. C. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55053-5 · Cited by 249 · see citing works

Regulation of steroid hormone biosynthesis: identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells

Epstein, L. F., & Orme-Johnson, N. R. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55054-7 · Cited by 247 · see citing works

MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis

Watari, H., Arakane, F., Moog-Lutz, C., Kallen, C. B., Tomasetto, C., Gerton, G. L., Rio, M.-C., Baker, M. E., & Strauss, J. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8462 · Cited by 247 · see citing works

Identity of the Site of Action of 3',5'-Adenosine Monophosphate and Adrenocortocotropic Hormone in Corticosteroidogenesis in Rat Adrenal and Beef Adrenal Cortex Slices*

Karaboyas, G. C., & Koritz, S. B. (1965) · Biochemistry · doi:10.1021/bi00879a014 · Cited by 247 · see citing works

Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones

Rone, M. B., Midzak, A. S., Issop, L., Rammouz, G., Jagannathan, S., Fan, J., Ye, X., Blonder, J., Veenstra, T., & Papadopoulos, V. (2012) · Molecular Endocrinology · doi:10.1210/me.2012-1159 · Cited by 247 · see citing works

The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule

Bose, H. S., Whittal, R. M., Baldwin, M. A., & Miller, W. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7250 · Cited by 227 · see citing works

Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial Infarction

Fraccarollo, D., Berger, S., Galuppo, P., Kneitz, S., Hein, L., Schütz, G., Frantz, S., Ertl, G., & Bauersachs, J. K. (2011) · Circulation · doi:10.1161/circulationaha.110.983023 · Cited by 226 · see citing works

Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol

Dillard, P., Lin, M., & Khan, S. A. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.08.013 · Cited by 225 · see citing works

Aromatase, breast cancer and obesity: a complex interaction

Bulun, S. E., Chen, D., Moy, I., Brooks, D. C., & Zhao, H. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2011.10.003 · Cited by 224 · see citing works

Intratumoral Aromatase in Human Breast, Endometrial, and Ovarian Malignancies

Sasano, H., & Harada, N. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.5.0342 · Cited by 223 · see citing works

Biology of estrogens in skin: implications for skin aging

Verdier‐Sévrain, S., Bonté, F., & Gilchrest, B. A. (2005) · Experimental Dermatology · doi:10.1111/j.1600-0625.2005.00377.x · Cited by 222 · see citing works

Steroidogenic Acute Regulatory Protein (StAR) Is A Sterol Transfer Protein

Kallen, C. B., Billheimer, J. T., Summers, S. A., Stayrook, S. E., Lewis, M., & Strauss, J. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.41.26285 · Cited by 217 · see citing works

Structure of the human steroidogenic acute regulatory (StAR) protein gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase

Sugawara, T., Lin, D., Holt, J. A., MARTIN, K. O., Javitt, N. B., Miller, W. L., & Strauss, J. F. (1995) · Biochemistry · doi:10.1021/bi00039a004 · Cited by 211 · see citing works

Prostaglandin E2 Via Steroidogenic Factor-1 Coordinately Regulates Transcription of Steroidogenic Genes Necessary for Estrogen Synthesis in Endometriosis

Attar, E., Tokunaga, H., Imir, G., Yilmaz, M. B., Redwine, D., Putman, M., Gurates, B., Attar, R., Yaegashi, N., Hales, D. B., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1180 · Cited by 207 · see citing works

Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction

Milliez, P., DeAngelis, N., Rücker‐Martin, C., Leenhardt, A., Vicaut, É., Robidel, E., Beaufils, P., Delcayre, C., & Hatem, S. N. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi478 · Cited by 204 · see citing works

The Mechanism of Action of Steroidogenic Acute Regulatory Protein (StAR)

Arakane, F., Kallen, C. B., Watari, H., Foster, J. A., Sepuri, N. B. V., Pain, D., Stayrook, S. E., Lewis, M., Gerton, G. L., & Strauss, J. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.26.16339 · Cited by 200 · see citing works

Intestinal Epithelial Cells Synthesize Glucocorticoids and Regulate T Cell Activation

Cima, I., Corazza, N., Dick, B., Fuhrer, A. C., Herren, S., Jakob, S., Ayuni, E., Mueller, C., & Brunner, T. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031958 · Cited by 200 · see citing works

Scavenger receptor class BI and selective cholesteryl ester uptake: partners in the regulation of steroidogenesis

Azhar, S., & Reaven, E. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00222-8 · Cited by 192 · see citing works

Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex

Simpson, E. R., & Waterman, M. R. (1983) · Canadian Journal of Biochemistry and Cell Biology · doi:10.1139/o83-088 · Cited by 189 · see citing works

Placental Steroid Hormone Synthesis: Unique Features and Unanswered Questions1

Strauss, J. F., Martı́nez, F., & Kiriakidou, M. (1996) · Biology of Reproduction · doi:10.1095/biolreprod54.2.303 · Cited by 187 · see citing works

Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein, StARProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998.

Miller, W. L., & Strauss, J. F. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00153-8 · Cited by 184 · see citing works

Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

Eck, M. V., Pennings, M., Hoekstra, M., Out, R., & van Berkel, T. J. C. (2005) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000169351.28019.04 · Cited by 178 · see citing works

REGULATION OF BILE ACID BIOSYNTHESIS

Vlahčevič, Z. R., Pandak, W., & Stravitz, R. T. (1999) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(05)70041-8 · Cited by 173 · see citing works

Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance

Bulun, S. E., Zeitoun, K. M., Takayama, K., & Sasano, H. (2000) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0250035 · Cited by 170 · see citing works

Glucocorticoid Receptor Localization in Normal and Asthmatic Lung

Adcock, I. M., Gilbey, T., Gelder, C. M., Chung, K. F., & Barnes, P. J. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.3.8810618 · Cited by 169 · see citing works

Steroidogenic Enzyme Gene Expression in the Human Heart

Kayes, K. M., & White, P. C. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6663 · Cited by 168 · see citing works

Regulation of steroidogenic acute regulatory protein expression and progesterone production in endometriotic stromal cells.

Tsai, S.-J., Wu, M.-H., Lin, C.-C., Sun, H. S., & Chen, H.-M. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.12.8082 · Cited by 155 · see citing works

THE METABOLISM OF TESTOSTERONE BY HUMAN MALE SCALP SKIN

Bingham, K. D., & SHAW, D. A. (1973) · Journal of Endocrinology · doi:10.1677/joe.0.0570111 · Cited by 153 · see citing works

Preparation of Antiserum to Rat Cytochrome P-450 Cholesterol Side Chain Cleavage, and Its Use for Ultrastructural Localization of the Immunoreactive Enzyme by Protein A-Gold Technique*

Farkash, Y., Timberg, R., & Orly, J. (1986) · Endocrinology · doi:10.1210/endo-118-4-1353 · Cited by 148 · see citing works

Oestrogen receptor proteins in malignant and fetal pancreas.

Greenway, B., Iqbal, M. J., Johnson, P. J., et al. (1981) · BMJ · doi:10.1136/bmj.283.6294.751 · Cited by 144 · see citing works

Aldosterone in obesity

Goodfriend, T. L., Egan, B. M., & Kelley, D. E. (1998) · Endocrine Research · doi:10.3109/07435809809032689 · Cited by 144 · see citing works

Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein

Bose, M., Whittal, R. M., Miller, W. L., & Bose, H. S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709221200 · Cited by 143 · see citing works

Localization of Type 5 17 -Hydroxysteroid Dehydrogenase, 3 -Hydroxysteroid Dehydrogenase, and Androgen Receptor in the Human Prostate by in Situ Hybridization and Immunocytochemistry

Elalfy, M., Luu-The, V., Huang, X., Berger, L., Labrie, F., & Pelletier, G. (1999) · Endocrinology · doi:10.1210/endo.140.3.6585 · Cited by 140 · see citing works

Localization of the Steroidogenic Acute Regulatory Protein in Human Tissues1

Pollack, S. E., Furth, E. E., Kallen, C. B., Arakane, F., Kiriakidou, M., Kozarsky, K., & Strauss, J. F. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4445 · Cited by 140 · see citing works

Interactions of oxysterols with membranes and proteins

Olkkonen, V. M., & Hynynen, R. (2009) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2009.02.004 · Cited by 140 · see citing works

Global Expression Changes of Constitutive and Hormonally Regulated Genes during Endometrial Neoplastic Transformation

Mutter, G. L., Baak, J. P. A., Fitzgerald, J. T., et al. (2001) · Gynecologic Oncology · doi:10.1006/gyno.2001.6352 · Cited by 138 · see citing works

The impact of ovulation on fallopian tube epithelial cells: evaluating three hypotheses connecting ovulation and serous ovarian cancer

King, S. M., Hilliard, T. S., Wu, L. Y., Jaffe, R. C., Fazleabas, A. T., & Burdette, J. E. (2011) · Endocrine Related Cancer · doi:10.1530/erc-11-0107 · Cited by 138 · see citing works

Transport of Cholesterol into Mitochondria Is Rate-limiting for Bile Acid Synthesis via the Alternative Pathway in Primary Rat Hepatocytes

Pandak, W. M., Ren, S., Marques, D., Hall, E., Redford, K. S., Mallonee, D. H., Bohdan, P. M., Heuman, D. M., Gil, G., & Hylemon, P. B. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205244200 · Cited by 135 · see citing works

Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis

Kitawaki, J., Kusuki, I., Koshiba, H., Tsukamoto, K., Fushiki, S., & Honjo, H. (1999) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00424-0 · Cited by 133 · see citing works

The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc

Black, S. M., Harikrishna, J. A., Szklarz, G. D., & Miller, W. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.15.7247 · Cited by 133 · see citing works

Origin of Aldosterone in the Rat Heart

Gómez-Sánchez, E. P., Ahmad, N., Romero, D. G., & Gómez-Sánchez, C. E. (2004) · Endocrinology · doi:10.1210/en.2004-0295 · Cited by 133 · see citing works

Cardiac Steroidogenesis in the Normal and Failing Heart

Young, M. J., Clyne, C. D., Cole, T. J., & Funder, J. W. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.7925 · Cited by 132 · see citing works

Aldosterone, mineralocorticoid receptor, and heart failure

Messaoudi, S., Azibani, F., Delcayre, C., & Jaisser, F. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.06.038 · Cited by 131 · see citing works

Extra‐adrenal production of corticosteroids

Davies, E., & MacKenzie, S. M. (2003) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2003.03867.x · Cited by 131 · see citing works

Effect of Truncated Forms of the Steroidogenic Acute Regulatory Protein on Intramitochondrial Cholesterol Transfer

Wang, X., Liu, Z., Eimerl, S., Timberg, R., Weiss, A. M., Orly, J., & Stocco, D. M. (1998) · Endocrinology · doi:10.1210/endo.139.9.6204 · Cited by 130 · see citing works

Intracrinology and The Skin

Labrie, F., Luu-The, V., Labrie, C., Pelletier, G., & El-Alfy, M. (2000) · Hormone Research in Paediatrics · doi:10.1159/000053264 · Cited by 128 · see citing works

Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development

Pennings, M., Meurs, I., Ye, D., Out, R., Hoekstra, M., van Berkel, T. J. C., & Eck, M. V. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.08.022 · Cited by 126 · see citing works

Expression of Type 2 11β-Hydroxysteroid Dehydrogenase and Corticosteroid Hormone Receptors in Early Human Fetal Life1

Condon, J. C., Gosden, C. M., Gardener, D., Nickson, P., Hewison, M., Howie, A. J., & Stewart, P. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.12.5302 · Cited by 125 · see citing works

27-Hydroxycholesterol: the first identified endogenous SERM

Umetani, M., & Shaul, P. W. (2011) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2011.01.003 · Cited by 124 · see citing works

Clinical disorders associated with abnormal cholesterol transport: mutations in the steroidogenic acute regulatory protein

Stocco, D. M. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00048-5 · Cited by 119 · see citing works

Expression of the steroidogenic acute regulatory protein mRNA in adrenal tumors and cultured adrenal cells

Liu, J., Heikkilä, P., Kahri, A. I., & Voutilainen, R. (1996) · Journal of Endocrinology · doi:10.1677/joe.0.1500043 · Cited by 114 · see citing works

Glucocorticoid regulation of surfactant components in immature lambs.

Ballard, P., Ning, Y., Polk, D., Ikegami, M., & Jobe, A. (1997) · American Journal of Physiology - Lung cellular and Molecular Physiology · doi:10.1152/ajplung.1997.273.5.l1048 · Cited by 114 · see citing works

Localization of the Steroidogenic Acute Regulatory Protein in Human Tissues

Pollack, S. E. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.12.4243 · Cited by 111 · see citing works

Neurosteroidogenesis in Rat Retinas

Guarneri, P., Guarneri, R., Cascio, C., Pavasant, P., Piccoli, F., & Papadopoulos, V. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63010086.x · Cited by 110 · see citing works

Colon cancer cells produce immunoregulatory glucocorticoids

Sidler, D., Renzulli, P., Schnoz, C., Berger, B., Schneider-Jakob, S., Flück, C., Inderbitzin, D., Corazza, N., Candinas, D., & Brunner, T. (2011) · Oncogene · doi:10.1038/onc.2010.629 · Cited by 107 · see citing works

Long-term (5-year) multinational experience with finasteride 1 mg in the treatment of men with androgenetic alopecia.

(2002) · PubMed · Cited by 102 · see citing works

Correlation of estrogen and progesterone receptors with histologic differentiation in endometrial adenocarcinoma.

McCarty, K. S., Barton, T. K., Fetter, B. F., et al. (1979) · PubMed · Cited by 101 · see citing works

N-218 MLN64, a protein with StAR-like steroidogenic activity, is folded and cleaved similarly to StAR

Bose, H. S., Whittal, R. M., Huang, M.-C., Baldwin, M. A., & Miller, W. L. (2000) · Biochemistry · doi:10.1021/bi000911l · Cited by 101 · see citing works

Changes in body composition and adipose tissue distribution after treatment of women with Cushing's syndrome

Lönn, L., Kvist, H., Ernest, I., & Sjöström, L. (1994) · Metabolism · doi:10.1016/0026-0495(94)90010-8 · Cited by 100 · see citing works

Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes

Beggah, A., Escoubet, B., Puttini, S., Cailmail, S., Delage, V., Ouvrard‐Pascaud, A., Bocchi, B., Peuchmaur, M. M., Delcayre, C., Farman, N., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102673599 · Cited by 100 · see citing works

Mitochondrial localization of a phosphoprotein that rapidly accumulates in adrenal cortex cells exposed to adrenocorticotropic hormone or to cAMP

Alberta, J. A., Epstein, L. F., Pon, L. A., & ORME-JOHNSON, N. R. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)94186-4 · Cited by 99 · see citing works

Steroid synthesis by primary human keratinocytes; implications for skin disease

Hannen, R. F., Michael, A. E., Jaulim, A., Bhogal, R., Burrin, J. M., & Philpott, M. P. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.11.059 · Cited by 96 · see citing works

Effect of cholesterol content on some physical and functional properties of mitochondria isolated from adult rat liver, fetal liver, cholesterol-enriched liver and hepatomas AH-130, 3924A and 5123

Feo, F., Canuto, R. A., Garcea, R., et al. (1975) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(75)90063-2 · Cited by 95 · see citing works

Adipocyte-derived products induce the transcription of the StAR promoter and stimulate aldosterone and cortisol secretion from adrenocortical cells through the Wnt-signaling pathway

Schinner, S., Willenberg, H. S., Krause, D., Schott, M., Lamounier‐Zepter, V., Krug, A. W., Ehrhart‐Bornstein, M., Bornstein, S. R., & Scherbaum, W. A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803508 · Cited by 89 · see citing works

In situ androgen producing enzymes in human prostate cancer

Nakamura, Y., Suzuki, T., Nakabayashi, M., et al. (2005) · Endocrine Related Cancer · doi:10.1677/erc.1.00914 · Cited by 89 · see citing works

Sterol 27-hydroxylase: high levels of activity in vascular endothelium.

Reiss, A. B., Martin, K. O., Javitt, N. B., et al. (1994) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40099-9 · Cited by 87 · see citing works

Establishment of human endometrial adenocarcinoma cell line containing estradiol-17β and progesterone receptors

Ishiwata, I., Ishiwata, C., Soma, C. T. M., et al. (1984) · Gynecologic Oncology · doi:10.1016/0090-8258(84)90212-9 · Cited by 86 · see citing works

Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency

Venihaki, M., Carrigan, A., Dikkes, P., & Majzoub, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.13.7336 · Cited by 85 · see citing works

Depot‐specific steroidogenic gene transcription in human adipose tissue

MacKenzie, S. M., Huda, S. S., Sattar, N. A., Fraser, R., Connell, J., & Davies, E. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03262.x · Cited by 83 · see citing works

Steroidogenic acute regulatory protein in the brain

Lavaque, E., Sierra, A., Azcoitia, I., & Garcia-Segura, L. M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.05.060 · Cited by 81 · see citing works

Expression of Sterol 27-Hydroxylase (CYP27A1) Enhances Cholesterol Efflux

Escher, G., Krozowski, Z. S., Croft, K. D., & Sviridov, D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212780200 · Cited by 81 · see citing works

26-Hydroxycholesterol: synthesis, metabolism, and biologic activities

Javitt, N. B. (1990) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42337-5 · Cited by 80 · see citing works

Human SP-A1 and SP-A2 genes are differentially regulated during development and by cAMP and glucocorticoids

McCormick, S. M., & Mendelson, C. R. (1994) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1994.266.4.l367 · Cited by 76 · see citing works

Nuclear Receptors and Inflammatory Diseases

Wang, K., & Wan, Y. Y. (2008) · Experimental Biology and Medicine · doi:10.3181/0708-mr-231 · Cited by 72 · see citing works

Transcriptional Regulation of the Cholesterol Side Chain Cleavage Cytochrome P450 Gene (CYP11A1) Revisited: Binding of GATA, Cyclic Adenosine 3′,5′-Monophosphate Response Element-Binding Protein and Activating Protein (AP)-1 Proteins to a Distal Novel Cluster ofcis-Regulatory Elements Potentiates AP-2 and Steroidogenic Factor-1-Dependent Gene Expression in the Rodent Placenta and Ovary

Sher, N., Yivgi-Ohana, N., & Orly, J. (2007) · Molecular Endocrinology · doi:10.1210/me.2006-0226 · Cited by 71 · see citing works

27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols

Fakheri, R. J., & Javitt, N. B. (2012) · Steroids · doi:10.1016/j.steroids.2012.02.006 · Cited by 71 · see citing works

Cloning and Expression of Glucocorticoid-induced Genes in Fetal Rat Lung Fibroblasts

Wang, J., Kuliszewski, M. J., Yee, W. M., Sedlackova, L., Xu, J., Tseu, I., & Post, M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.6.2722 · Cited by 69 · see citing works

Overexpression of steroidogenic acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI

Taylor, J. M. W., Borthwick, F., Bartholomew, C., & Graham, A. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq015 · Cited by 68 · see citing works

Expression of Steroidogenic Genes in Maternal and Extraembryonic Cells During Early Pregnancy in Mice1

Arensburg, J., Payne, A. H., & Orly, J. (1999) · Endocrinology · doi:10.1210/endo.140.11.7144 · Cited by 66 · see citing works

Hepatic mitochondrial cytochrome P -450: Isolation and functional characterization

Sato, R., Atsuta, Y., Imai, Y., et al. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5477 · Cited by 66 · see citing works

Role of Cytochromes P-450 in the Biosynthesis of Steroid Hormones

Hall, P. F. (1985) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60065-5 · Cited by 65 · see citing works

Detection of the steroidogenic acute regulatory protein, StAR, in human liver cells

Hall, E. A., Ren, S., Hylemon, P. B., Rodríguez‐Agudo, D., Redford, K. S., Marques, D., Kang, D., Gil, G., & Pandak, W. M. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2005.01.004 · Cited by 65 · see citing works

Overexpression of mitochondrial cholesterol delivery protein, StAR, decreases intracellular lipids and inflammatory factors secretion in macrophages

Ning, Y., Bai, Q., Lu, H., Li, X., Pandak, W. M., Zhao, F., Chen, S., Ren, S., & Yin, L. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.09.006 · Cited by 64 · see citing works

The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes

Tiala, I., Suomela, S., Huuhtanen, J., Wakkinen, J., Hölttä-Vuori, M., Kainu, K., Ranta, S., Turpeinen, U., Hämäläinen, E., Jiao, H., et al. (2007) · Journal of Molecular Medicine · doi:10.1007/s00109-006-0155-0 · Cited by 64 · see citing works

Sex steroid synthesis in human skin in situ: the roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin

Inoue, T., Miki, Y., Abe, K., Hatori, M., Hosaka, M., Kariya, Y., Kakuo, S., Fujimura, T., Hachiya, A., Honma, S., et al. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.05.005 · Cited by 62 · see citing works

Sex-Steroid Enzymes, Aromatase and 5α-Reductase in the Pancreas: A Comparison of Normal Adult, Foetal and Malignant Tissue

Iqbal, M. J., Greenway, B., Wilkinson, M. L., et al. (1983) · Clinical Science · doi:10.1042/cs0650071 · Cited by 60 · see citing works

Differential Regulation of Glucocorticoid Synthesis in Murine Intestinal EpithelialVersusAdrenocortical Cell Lines

Müeller, M., Atanasov, A. G., Cima, I., Corazza, N., Schoonjans, K., & Brunner, T. (2006) · Endocrinology · doi:10.1210/en.2006-0591 · Cited by 59 · see citing works

The use of genetic manipulation of MA-10 Leydig tumor cells to demonstrate the role of mitochondrial proteins in the acute regulation of steroidogenesis

Stocco, D. M., & Ascoli, M. (1993) · Endocrinology · doi:10.1210/endo.132.3.8382603 · Cited by 58 · see citing works

The Roles of Circulating High-Density Lipoproteins and Trophic Hormones in the Phenotype of Knockout Mice Lacking the Steroidogenic Acute Regulatory Protein

Ishii, T., Hasegawa, T., Pai, C.-I., Yivgi-Ohana, N., Timberg, R., Zhao, L., Majdič, G., Chung, B., Orly, J., & Parker, K. L. (2002) · Molecular Endocrinology · doi:10.1210/me.2001-0320 · Cited by 56 · see citing works

Glucocorticoid Activity during Lung Maturation Is Essential in Mesenchymal and Less in Alveolar Epithelial Cells

Habermehl, D., Parkitna, J. M. R., Kaden, S., Brügger, B., Wieland, F., Gröne, H., & Schütz, G. (2011) · Molecular Endocrinology · doi:10.1210/me.2009-0380 · Cited by 51 · see citing works

Androgens, androgen receptors, antiandrogens and the treatment of prostate cancer.

Griffiths, K., Ms, M., & Nicholson, R. I. (1997) · PubMed · Cited by 49 · see citing works

Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure

Ohtani, T., Mano, T., Hikoso, S., et al. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e328326cb04 · Cited by 47 · see citing works

Transcription of Steroidogenic Acute Regulatory Protein in the Rodent Ovary and Placenta: Alternative Modes of Cyclic Adenosine 3′, 5′-Monophosphate Dependent and Independent Regulation

Yivgi-Ohana, N., Sher, N., Melamed‐Book, N., Eimerl, S., Koler, M., Manna, P. R., Stocco, D. M., & Orly, J. (2008) · Endocrinology · doi:10.1210/en.2008-0541 · Cited by 46 · see citing works

The effects of inflammatory cytokines on steroidogenic acute regulatory protein expression in macrophages

Ma, Y., Ren, S., Pandak, W. M., Li, X., Ning, Y., Lu, C., Zhao, F., & Yin, L. (2007) · Inflammation Research · doi:10.1007/s00011-007-6133-3 · Cited by 42 · see citing works

Second trimester medical abortion with mifepristone and gemeprost: a review of 956 cases

Tang, O. S., Thong, K. J., & Baird, D. T. (2001) · Contraception · doi:10.1016/s0010-7824(01)00219-0 · Cited by 40 · see citing works

Role of lipid transfer proteins in the abnormal lipid content of Morris hepatoma mitochondria and microsomes.

Crain, R. C., Clark, R. W., & Harvey, B. E. (1983) · PubMed · Cited by 40 · see citing works

CCHCR1 Is Up-Regulated in Skin Cancer and Associated with EGFR Expression

Suomela, S., Elomaa, O., Skoog, T., Ala‐aho, R., Jeskanen, L., Pärssinen, J., Latonen, L., Grenman, R. A., Kere, J., Kähäri, V., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006030 · Cited by 39 · see citing works

Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd.3)

Ning, Y., Chen, S., Li, X., Ma, Y., Zhao, F., & Yin, L. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.093 · Cited by 37 · see citing works

Neurosteroid inhibition of cell death

Waters, S. L., Miller, G. W., Aleo, M. D., et al. (1997) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1997.273.6.f869 · Cited by 37 · see citing works

Cardiac Synthesis of Aldosterone: Going, Going, Gone… ?

Funder, J. W. (2004) · Endocrinology · doi:10.1210/en.2004-1057 · Cited by 36 · see citing works

Steroidogenic acute regulatory protein mRNA expression in adrenal tumours

Zenkert, S., Schubert, B., Faßnacht, M., Beuschlein, F., Allolio, B., & Reincke, M. (2000) · European Journal of Endocrinology · doi:10.1530/eje.0.1420294 · Cited by 36 · see citing works

Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia

Hoffmann, R. (2003) · Dermatology · doi:10.1159/000068475 · Cited by 36 · see citing works

The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain

King, S. R., Ginsberg, S. D., Ishii, T., Smith, R. G., Parker, K. L., & Lamb, D. J. (2004) · Endocrinology · doi:10.1210/en.2003-1740 · Cited by 34 · see citing works

Synthesis of Steroids in Pancreas

Morales, A., Cuéllar, A., Ramírez, J., Vilchis, F., & Díaz‐Sánchez, V. (1999) · Pancreas · doi:10.1097/00006676-199907000-00006 · Cited by 33 · see citing works

On the stereospecificity of cholestanetriol 26-monooxygenase.

Atsuta, Y., & Okuda, K. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52520-0 · Cited by 32 · see citing works

Genes Involved in the Adrenal Pathway of Glucocorticoid Synthesis Are Transiently Expressed in the Developing Lung

Provost, P. R., & Tremblay, Y. (2005) · Endocrinology · doi:10.1210/en.2005-0077 · Cited by 32 · see citing works

Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer

Eichholz, A., Ferraldeschi, R., Attard, G., & Bono, J. S. D. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.038 · Cited by 32 · see citing works

Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages

Borthwick, F., Taylor, J. M. W., Bartholomew, C., & Graham, A. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.02.042 · Cited by 31 · see citing works

Detection of corticosteroid type I binding sites in heart

Barnett, C. A., & Pritchett, E. L. (1988) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(88)90060-3 · Cited by 30 · see citing works

Expression and cellular localization of uterine side-chain cleavage cytochrome P450 messenger ribonucleic acid during early pregnancy in mice.

Schiff, R., Arensburg, J., Itin, A., et al. (1993) · Endocrinology · doi:10.1210/endo.133.2.8344198 · Cited by 29 · see citing works

Steroidogenic Acute Regulatory Protein-binding Protein Cloned by a Yeast Two-hybrid System

Sugawara, T., Shimizu, H., Hoshi, N., Nakajima, A., & Fujimoto, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302291200 · Cited by 29 · see citing works

Steroidogenic Acute Regulatory Protein Expression in the Central Nervous System

King, S. R., & Stocco, D. M. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00072 · Cited by 28 · see citing works

Expression and Modulation of Steroidogenic Acute Regulatory Protein Messenger Ribonucleic Acid in Rat Cardiocytes and after Myocardial Infarction

Casal, A. J., Silvestre, J., Delcayre, C., & Capponi, A. M. (2003) · Endocrinology · doi:10.1210/en.2002-220943 · Cited by 28 · see citing works

Expression of cytochrome P450scc mRNA and protein in the rat kidney from birth to adulthood

Valle, L. D., Toffolo, V., Vianello, S., Belvedere, P., & Colombo, L. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2003.11.001 · Cited by 28 · see citing works

Cardiac Steroidogenesis—New Sites of Synthesis, or Much Ado About Nothing?

Gómez-Sánchez, C. E., & Gómez-Sánchez, E. P. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.11.8102 · Cited by 27 · see citing works

Prematurity prevention: the role of progesterone

da Fonseca, E. B., Bittar, R. E., Damião, R. D. S., & Zugaib, M. (2009) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3283294770 · Cited by 25 · see citing works

Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia

Chen, W., Tsai, S.-J., Liao, C.-Y., Tsai, R.-Y., Chen, Y.-J., Pan, B.-J., Hung, C.-L., & Zouboulis, C. C. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700442 · Cited by 25 · see citing works

Expression of SR–BI receptor and StAR protein in rat ocular tissues

Provost, A. C., Péquignot, M. O., Sainton, K. M., Gadin, S., Sallé, S., Marchant, D., Hales, D. B., & Abitbol, M. M. (2003) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2003.09.001 · Cited by 23 · see citing works

Transcriptional regulation of macrophage cholesterol trafficking by PPARα and LXR

Chinetti, G., Fruchart, J., & Staels, B. (2006) · Biochemical Society Transactions · doi:10.1042/bst0341128 · Cited by 23 · see citing works

Fertility drug use and risk of ovarian tumors: a debated clinical challenge

Gadducci, A., Guerrieri, M. E., & Genazzani, A. R. (2012) · Gynecological Endocrinology · doi:10.3109/09513590.2012.705382 · Cited by 22 · see citing works

Aldosterone-synthase overexpression in heart: a tool to explore aldosterone's effects.

Heymes, C., Garnier, A., Fuchs, S., Bendall, J., Nehmé, J., Ambroisine, M., Robidel, E., Swynghedauw, B., Milliez, P., & Delcayre, C. (2004) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2003.10.022 · Cited by 22 · see citing works

Purification and characterization of the activated mineralocorticoid receptor from rat myocardium

Lázár, G., Pagano, M., & Agarwal, M. K. (1990) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(90)90192-y · Cited by 22 · see citing works

17β-hydroxysteroid dehydrogenase activity in canine pancreas

Mendoza‐Hernández, G., López-Solache, T., Rendón, J. L., et al. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80724-1 · Cited by 21 · see citing works

Localization and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1) in the adult rat kidney

Pagotto, M. A., Roldán, M. L., Pagotto, R., Lugano, M. C., Pisani, G. B., Rogic, G., Molinas, S. M., Trumper, L., Pignataro, O. P., & Monasterolo, L. A. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.10.020 · Cited by 20 · see citing works

Expression of enzyme associated with steroid hormone synthesis and local production of steroid hormone in endometrial carcinoma cells

Sugawara, T., Nomura, E., & Fujimoto, S. (2004) · Journal of Endocrinology · doi:10.1677/joe.0.1800135 · Cited by 19 · see citing works

StAR and progesterone producing enzymes (3β‐hydroxysteroid dehydrogenase and cholesterol side‐chain cleavage cytochromes P450) in human epithelial ovarian carcinoma: Immunohistochemical and real‐time PCR studies

Abd‐Elaziz, M., Moriya, T., Akahira, J., et al. (2005) · Cancer Science · doi:10.1111/j.1349-7006.2005.00040.x · Cited by 18 · see citing works

Mitochondrial Cholesterol Transporter, StAR, Inhibits Human THP‐1 Monocyte‐Derived Macrophage Apoptosis

Bai, Q., Li, X., Ning, Y., et al. (2009) · Lipids · doi:10.1007/s11745-009-3375-6 · Cited by 16 · see citing works

Cholesterol efflux and the effect of combined treatment with niacin and chromium on aorta of hyperlipidemic rat

Süren‐Castillo, S., Döger, M. M., Bolkent, Ş., & Yanardağ, R. (2007) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-007-9623-2 · Cited by 12 · see citing works

Targeting the aldosterone pathway in cardiovascular disease

Gustafsson, F., Azizi, M., Bauersachs, J. K., Jaisser, F., & Rossignol, P. (2011) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2011.01004.x · Cited by 9 · see citing works

Testosterone Biotransformation by the Isolated Perfused Canine Pancreas

del Castillo, C. F., Díaz‐Sánchez, V., Varela‐Fascinetto, G., et al. (1991) · Pancreas · doi:10.1097/00006676-199101000-00014 · Cited by 9 · see citing works

Differential Expression of Steroidogenic Factors 1 and 2, Cytochrome P450scc, and Steroidogenic Acute Regulatory Protein in Human Pancreas

Morales, A., Vilchis, F., Chávez, B. A., Morimoto, S., Chan, C. H. F., Robles‐Díaz, G., & Díaz‐Sánchez, V. (2008) · Pancreas · doi:10.1097/mpa.0b013e318168dd8c · Cited by 9 · see citing works

Overexpression of the steroidogenic acute regulatory protein increases the expression of ATP-binding cassette transporters in microvascular endothelial cells (bEnd.3)

Ning, Y., Ren, S., Zhao, F., et al. (2010) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b0900369 · Cited by 7 · see citing works

The pattern of gene expression and possible relation of steroidogenic genes in oligodendroglial tumors

Kim (1992) · International Journal of Oncology · doi:10.3892/ijo_00000140 · Cited by 4 · see citing works

11-Oxygenated androgens in health and disease

Turcu, A. F., Rege, J., Auchus, R. J., & Rainey, W. E. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-020-0336-x · Cited by 217 · see citing works

Intracrine androgen biosynthesis, metabolism and action revisited

Schiffer, L., Arlt, W., & Storbeck, K.-H. (2018) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.08.016 · Cited by 217 · see citing works

Steroid biosynthesis in adipose tissue

Li, J., Papadopoulos, V., & Vihma, V. (2015) · Steroids · doi:10.1016/j.steroids.2015.03.016 · Cited by 130 · see citing works

Current knowledge on the acute regulation of steroidogenesis

Selvaraj, V., Stocco, D. M., & Clark, B. J. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy102 · Cited by 118 · see citing works

Adrenal Androgens and Androgen Precursors-Definition, Synthesis, Regulation and Physiologic Actions

Turcu, A., Smith, J. M., Auchus, R., & Rainey, W. E. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140006 · Cited by 113 · see citing works

An intracrine view of sex steroids, immunity, and metabolic regulation

Rubinow, K. B. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.03.001 · Cited by 82 · see citing works

Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity

Slominski, A. T., Manna, P. R., & Tuckey, R. C. (2014) · Experimental Dermatology · doi:10.1111/exd.12376 · Cited by 79 · see citing works

Updated survey of the steroid-converting enzymes in human adipose tissues

Tchernof, A., Mansour, M. F., Pelletier, M., Boulet, M.-M., Nadeau, M., & Luu-The, V. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.11.011 · Cited by 73 · see citing works

Leydig Cell Aging: Steroidogenic Acute Regulatory Protein (StAR) and Cholesterol Side‐Chain Cleavage Enzyme

Luo, L., CHEN, H., & Zirkin, B. R. (2001) · Journal of Andrology · doi:10.1002/j.1939-4640.2001.tb02165.x · Cited by 103 · see citing works

Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells

Ellison, D. D., Munden, A. L., & Levchenko, A. (2009) · Molecular BioSystems · doi:10.1039/b905602e · Cited by 41 · see citing works

Seasonal expressions of SF-1, StAR and P450scc in the scent glands of the muskrats (Ondatra zibethicus)

Xie, W., Tang, Z., Xu, L., et al. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105766 · Cited by 16 · see citing works

Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein, StARProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998.

Miller, W. L., & Strauss, J. F. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00153-8 · Cited by 184 · see citing works

Autocrine/Paracrine Function of Parathyroid Hormone-Related Peptide in Rat Osteoblast-like Cells

Enomoto, H., Yamashita, S., Usa, T., et al. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.1353 · Cited by 16 · see citing works